糖合成

Thirteen proteins were identified by peptide mass fingerprinting or peptide sequence analysis,including putative nucleoside diphosphate kinase,elongation factor 1-gamma,triosephosphate isomerase,60S acidic ribosomal protein P0,heat shock protein 75 kDa,similar to heat shock 70kD protein binding protein,annexin I,hypothetical protein FLJ34423,microtubule-actin crosslinking factor 1,lamin B2,ATP synthase alpha chain,mitochondrial precursor,proteasome subunit alpha type 6.These identified proteins involved in energy metabolism,translation and RNA processing,protein folding,redox regulation,cell structure and cell signaling.

双向凝胶电泳结果显示，甲醛刺激后19个蛋白斑点发生变化，肽指纹图谱及肽序列标签鉴定了其中13个蛋白斑点，已鉴定的蛋白包括二磷酸核苷酸激酶、延长因子1-γ，磷酸丙糖异构酶、60S酸性核糖体蛋白P0、75kDa热休克蛋白、70kD热休克蛋白样结合蛋白、钙依赖磷脂结合蛋白I、假想蛋白FLJ34423、微管-肌动蛋白交叉连接因子1、核纤层蛋白B2、ATP合成酶α链、蛋白酶体α亚基6，这些蛋白功能涉及转录调节、蛋白折叠、信号传导、能量代谢、细胞骨架等各个方面。

Neomycin on ammonia acid can lead to vitamin B12 deficiency; phenytoin, methotrexate, B ammonia pyrimidine, methyl benzyl ammonium pyrimidine and Triamterene, etc. can cause folic acid deficiency; mercaptopurine, 5 - fluoro-piperidine urine density, Ara-C, etc. can interfere with nucleic acid synthesis, these drugs can lead to megaloblastic anemia.

新霉素、对氨水杨酸可导致维生素B12缺乏；苯妥英钠、甲氨蝶呤、乙氨嘧啶、甲基苄氨嘧啶及氨苯蝶啶等可引起叶酸缺乏；巯嘌呤、5--氟尿密啶、阿糖胞苷等能够干扰核酸的合成，这些药物都可导致巨幼红细胞性贫血。

In the presence of acid catalyst, APG is formed by use C8 - C14 monohydric alcohols、low-carbon alcohol and glucose monohydrate with one step synthesis reaction, and it could be used without fractionation in most applications.

在酸性催化剂存在下，用C8～C14单羟基醇和低碳醇与一水合葡萄糖反应，一步合成较高纯度，在大多数应用场合不经分馏而直接使用的浅色烷基糖苷。

Herein, we synthesized six metalloporphyrins linked with stable nitroxyl radials, and evaluated their catalytic activity for the oxidation of glycosyl sulfides to glycosyl sulfoxides.

本论文设计、合成了6个连有稳定氮氧自由基的卟啉及其铁、锰的络合物，考察了它们对糖基硫苷等硫醚类化合物氧化成亚砜的催化性能。

Usage: useful for pharmaceutical intermediate,especially useful for intermediate of synthesis aids inhibitor and high temperature resistant resins and metallocen catalyst for olefine polymerization.

用途：用作各种医药合成中间体，特别是抗艾兹病药物，治疗糖脲病药物以及治疗心律不齐病药物的中间体以及烯烃聚合用金属茂络合物催化剂配位体和透明的耐热性树脂原料。

First Total Synthesis of OSW-1, an Exceptionally Potent Antitumor Saponin OSW-1, an acylated disaccharide steroidal saponin isolated by Sashida in 1992 from a plantnamed Ornithogalum saundersiae without any medicinal background, was one of the most potent antitumor agent to date with the cytotoxicity activity as 100 times potent as many other anticancer drugsclinically used.

一、极强抗癌活性皂甙——虎眼万年青皂甙(OSW-1)的首次全合成：虎眼万年青皂甙OSW-1是一个新近由日本化学家从非药用植物Ornithogalumsaundersiae中分离出来的具有极强抗癌活性的酰化二糖甾体皂甙，它对多种癌细胞的毒性比临床用药高100倍以上。

Our results indicate that biosynthesis of UDP-sugars that are precursors of pectic polymers is important for cotton fiber elongation.

综合分析表明，果胶前体核苷糖的生物合成对棉纤维细伸长非常重要，并且受乙烯信号的调控。

Synthesis with carbocyclic compounds, such as cyclodienylsilane, quinic acid and norbornene etc, as starting materials is discussed in detail.

重点介绍了以环二烯基硅烷、奎宁酸、降冰片烯等碳环化合物为原料合成碳环糖的进展。

ABSTRACT AIM: In order to find new type of antitumor compounds and study the contribution of hydroxyl groups on the sugar part to the antitumor activity of 8-Cl-adenosine, the retinoid analogs of adenosine and the derivatives of 8-Cl-adenosine were synthesized.

目的： 为寻找新型抗肿瘤化合物和探讨糖环羟基对8-Cl-腺苷的抗肿瘤活性的影响，合成了腺苷的维甲类似物和8-Cl-腺苷衍生物。

In this thesis, two synthetic routes for the incorporation of sugar moiety into C5(5") or C3(3") of salicylaldehyde part of Salen Mn complex were designed and several corresponding compounds were prepared, as carbohydrate derivatives are widely used in asymmetric catalytic reactions.

鉴于糖类衍生物在不对称催化反应中的广泛应用，设计了两条分别在Salen Mn配合物水杨醛部分C5(5′)、C3(3′)位并入糖基的路线并合成了相应的化合物。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。