糖合成

This study has provided a new way for the enzymatic synthesis of trehalose.

本研究结合基因工程和酶工程方法，为合成海藻糖的研究提供了新的思路。

Objective:To investigate the effect of high glucose on the production of reactive oxygen species and type IV collagen in human mesangial cells and the intervention of tea polyphenols.

目的：探讨高糖对人肾小球系膜细胞活性氧、Ⅳ型胶原合成的影响及其茶多酚的干预作用。

Zona reticularis is responsible for glucocorticoid and sex hormone synthesis.

网状带负责合成糖皮质激素和性激素。（缩略图，点击图片链接看原图

Zona fasciculata is responsible for glucocorticoid synthesis.

束状带是合成糖皮质激素的地方。（缩略图，点击图片链接看原图

Studies also indicated that genistein exsists not only in soybeans but also in many kinds of plants such as vegetables and fruits.As a potential anticancer agent, the actional mechanisms of genistein mainly includes as follows:First, genistein can depress the activity of protein tyrosine kinase and transduction pathways for the phosphorylation of receptors and mitosis signal. So genistein can lead to cells' proliferation depressed. Second, genistein has minimal effects of phytoestrogens. It can be combined with estrogen receptor and improve the synthesis of cellular sex hormone binding glulobin, and improve the activity of UDP-glucuronyl transferase. Through these pathways, it can inhibit the cell activity of breast cancer and prostate cancer.

作为一个很有潜力的抗肿瘤物质，三羟异黄酮的作用机制主要包括：①抑制蛋白酪氨酸激酶活性，可阻抑PTK引起的受体磷酸化和有丝分裂的信号传递，导致癌细胞增殖受抑；②弱雌激素作用：可通过与体内雌激素受体结合，并可增加细胞内性激素结合球蛋白的合成，增加UDP-葡糖醛酸转移酶的活性等途径抑制乳腺癌和前列腺癌细胞活性；③拓扑酶Ⅰ和Ⅱ抑制剂，抑制细胞活性；④上调细胞周期性负性调节因子P21WAF1/CIP1的表达，使之负性调节因子作用增强；⑤可阻止胰岛素样生长因子-Ⅰ、肝细胞生长因子和神经生长因子的作用而抑制肿瘤生长；⑥其他：抗氧化作用、抑制热休克蛋白、诱导细胞凋亡、抑制新生血管生成和抑制多种耐药相关蛋白等。

The invention relates to the synthesis of N-aryl group-3-(4-Beta-D-pyran allose glycoside phenyl)-5-formyl isoxazole-4-formamide and discloses a helicid derivative which can improve the functions of a central nervous system and the preparation method thereof; wherein, the compound has good sedative, hypnotic and anti-convulsant effects and is taken in the 2000 edition Chinese Pharmacopoeia with the drug name of helicid tablets.

N-芳基-3-(4-β-D-吡喃阿洛糖苷苯基)-5-甲酰基异唑-4-甲酰胺的合成，发明公开了具有改善中枢神经系统功能的豆腐果苷类衍生物，及其制备方法。该类化合物具有良好的镇静、安眠、抗惊厥作用。目前已以药品名&神衰果素片&被收入2000年版《中国药典》。

With α-D-glucose as raw material, 3-O-benzoyl-1,2,5,6-O-diisopropylidene-α-D-allofuranose was synthesized by isopropylene protection , oxidation, reduction and benzoylation.

以α-D-葡萄糖为原料，经异丙叉基保护、氧化、还原、苯甲酰化反应合成3-苯甲酰基-1，2，5，6-氧-二异丙叉基-α-D-呋喃阿洛糖。

The common building block of them was synthesized by firstly glycosylation of an appropriately protected glucose with diosgenin, then introduction of a rhamnosyl residue to the 2-OH at Glu, finally freeing the 4-OH at Glu by selectively benzoylation of 6-OH.

我们先将适当保护的葡萄糖接在薯蓣甙元上，然后选择性地保护葡萄糖的 3 位羟基，在 2 位上引入一个鼠李糖，接下来选择性地保护葡萄糖的 6 位羟基，得到了上面三个皂甙的共同合成子。

The common building block of them was synthesized by firstly glycosylationof an appropriately protected glucose with diosgenin, then introduction of a rhamnosyl residue to the 2-OH at Glu, finally freeing the 4-OH at Glu by selectively benzoylation of 6-OH.

我们先将适当保护的葡萄糖接在薯蓣甙元上，然后选择性地保护葡萄糖的3位羟基，在2位上引入一个鼠李糖，接下来选择性地保护葡萄糖的6位羟基，得到了上面三个皂甙的共同合成子。

In model plant Arabidopsis thaliana, also from Brassicaceae, the TRANSPARENT TESTA 12 (TT12, AtTT12) gene is seed coat-specific and encodes a vacuolar flavonoid/H+ antiporter, transporting cytoplasm-synthesized glycosylated flavan-3-ols to the vacuoles for further polymerization into seed coat pigments.

同属十字花科的模式植物拟南芥中，种皮特异表达的TT12（透明种皮12，AtTT12）基因编码一种液泡型类黄酮/H+-逆向转运蛋白，将胞浆内合成的糖苷化的黄烷-3-醇转运到液泡中，供进一步聚合形成种皮色素。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。