糖化

The Tg for a mass ratio mixture of Galpi and sucrose of 0.3/1 was greater than 0 and was similar to that of the same ratio mixture of raffinose to sucrose, indicating that Galpi as well as oligosaccharides plays an important role in glass formation.

甲基肌醇半乳吡喃糖和蔗糖以0.3对1重量浓度混合比例，其玻璃质化转移温度在0℃以上，且近似於相同比例之寡糖类和蔗糖混合，显示甲基肌醇半乳吡喃糖和寡糖类在玻璃质化形成上扮演重要的角色。

For amylase way to hydrolyze and produce glucose, Liguefaction temperature, PH value and saccharification time condition are strictly controlled, contents of disaccharide, trisaccharide and the Polysaccharides which are over tetrasaccharide can be reduced, and glucose quality can be improved.

淀粉酶法水解生产葡萄糖，严格控制好液化的温度、H值、化时间条件，可降低二糖三糖四糖以及四糖以上多糖的含量，提高葡萄糖的质量。

Compound 9 is glycosylated in the presence of TMSOTf with rhamose-derived trichloroacetimidates to provide target trisaccharide Saponin 1, oleanolic acid 3-yl-2,4-di-O-a-L-rhamnopyranosyl -p-D-glucopyranosideCoumpond 18 is prepared with oleanic acid and Bromide 11 through phase-thansfer catalysis glycosylation manner.

三糖皂苷Saponin 1是以葡萄糖齐墩果酸皂苷为起始原料，用BBTZ(1-苯甲酰苯并噻唑)选择性保护葡萄糖3′，6′-羟基得到化合物9，然后以化合物9为糖基受体，进行一步糖苷化可以在化合物9的2′，4′-羟基上同时引入两分子鼠李糖，最后脱掉所有的保护基得到目标化合物Saponin1。

The molar ratio of sulfate ions to carboxylate ions is determined by conductometric titration method and the molecular weight is tested by high performance gel permeation chromatography. The precision of these two methods is also studied. To improve the detection sensitivity, guanidine hydrochloride is used as the best derivation reagent of 911. A systematic research is done on the optimum derivatization condition of 911 and Guanidine hydrochloride. The M /G ratio of 911 has direct relation to its biological activity.

论文首先对911的基本理化性质进行了系统的分析，以电导滴定法和高效凝胶渗透色谱法分别测定了分子中硫酸根羧酸根的比值和911的分子量，并探讨了两种分析方法的精密度。911分子没有紫外吸收，为提高检测灵敏度，本文采用荧光标记法，通过对三种荧光试剂与几种寡糖和多糖衍生效果的综合比较，最终确定了盐酸胍为最佳衍生试剂，并以911为代表详细探讨了衍生化反应的最优条件。911糖链结构与褐藻胶主链结构类似，以甘露糖醛酸和古罗糖醛酸的嵌段形式存在，分子中M/G比值与911的物理化学性质和生物活性有直接关系。

AIM: To investigate the effects of crocetin on receptor for advanced glycation end products mRNA expression in bovine endothelial cells induced by advanced glycation end products and the possible mechanisms involved.

目的：研究西红花酸对晚期糖基化终产物诱导牛内皮细胞中晚期糖基化终产物受体mRNA表达的抑制作用，并探讨其可能机制。

During the incubation of purified α-synuclein with fructose or glucose, it was observed that the protein intrinsic fluorescence at 308 nm decreased while the fluorescence of glycated derivant at 447 nm increased.

将纯化后的α-synuclein分别与果糖和葡萄糖孵育，通过内源荧光、非酶糖基化衍生物特征荧光、圆二色光谱以及电子显微镜等技术进行检测发现：α-synuclein 与还原糖共同孵育后，308 nm内源荧光强度明显降低，同时在447 nm产生一个非酶糖基化衍生物特征荧光。

Four new salicylaldehyde derivatives with a glucose or mannose moiety were synthesized with 2-tert-butylphenol or 4-tert-butylphenol as the starting material, followed by the formylation, chloromethylation, nucleophilic substitution reaction with the desired carbohydrate. The salicylaldehyde derivatives condensed with ethylenediamine to give the Schiff bases, which coordinated with Mn to afford four novel sugar-based Salen Mn complexes.

首先，分别以2-叔丁基苯酚和4-叔丁基苯酚为起始原料，经过甲酰化反应、氯甲基化反应、和糖类衍生物的亲核取代反应制得了四种新型并入葡萄糖基或甘露糖基的水杨醛衍生物，将它们与乙二胺缩合生成希夫碱配体，得到的配体与过渡金属Mn~(3+)配位制备出四种新型含糖基的Salen Mn配合物。

Based on the methylation analysis of the glycan and 〓C NMR spectroscopy of the glycoconjugate, one of the probably structure of repeat unit of the glycoconjugate was estimated as follow:- [→4 βGlcp (1→4)βGlcp (1→4)βGlcp (1→4)βGlcp (1→4)βGlcp (1→4)βGlcp (1→4)-βGlcp (1→4)βGlcp (1→] 〓→4)βGlcp (1→3)βManp (1→3)βRhap (1→3)βRhap (1→3)-↓↓βGalp βArap -βRhap (1→3)βRhap 1→ GFPE, which was the extracellular polysaccharide, was sulfated and the production was called GFPEs, which sulfated radicals content was 20.02%.

以甲基化反应及核磁共振的方法分析糖链结构，假设糖链GFPI-g具有重复结构单元，其可能的一种重复单元结构为：〓对灰数花胞外多糖GFPE的硫酸化修饰产物命名为GFPE-s，硫酸根含量为20.02％。

Matrix extracelluar phosphoglycoprotein, which is one of the matrix extracelluar non-collage-nous proteins, is expressed in bone, teeth and renal proximal convoluted tubules.

细胞外基质磷酸糖蛋白是一种细胞外基质的非胶原性磷酸化糖蛋白，主要表达于骨组织、牙组织和肾近球小管中，在骨形成矿化以及调节磷吸收方面发挥重要作用。

The results showed that Tang-an-kang could respond symptomatically, lower blood-sugar, diminish urinary protein, regulate endogenous creatinine clearance rate and lipid metabolism etc. It was suggested that Tang-an-kang had a good action on improvement lipid metabolism, diminishing urinary protein and renal function protection.

结果表明：糖安康治疗组在改善DN患者临床症状，降低血糖、糖基化血红蛋白及血肌酐，减少尿蛋白及尿白蛋白，调节内生肌酐清除率，降低血与尿β2微球蛋白，调节脂代谢，改善血液流变性等方面，疗效均优于单用西药的对照组，提示糖安康有良好改善糖脂代谢、减少尿蛋白、保护肾功能的作用。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。