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糖化

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The immunoregulation activity of SPG-1 mainly existed in the part of sugar chain, but keeping its molecular structure intact had some effects on its immunoregulation activity; SPG sulphation had reducing effects on the immunoregulation of SPG-1, whereas, after medium and low acetification of SPG, the immunoregulation of SPG was enhanced. Conversely after high acetification, the immunoregulation of SPG-1 decreased, that is, after introducing sulfuric and acetic acid base in SPG-1, its immunoregulation changed. All of these indicated the structure of SPG-1 was closely connected with its immune activity.⑤.

甘薯糖蛋白SPG-1的免疫调节活性主要在其糖链部分,但保持分子结构的完整性对其免疫调节的活性有一定的作用;甘薯糖蛋白硫酸化对甘薯糖蛋白SPG-1的免疫调节有降低作用,而中、低度乙酰化后,可提高甘薯糖蛋白的免疫调节作用,高度乙酰化后则降低其免疫调节作用,即甘薯糖蛋白引入乙酰基和硫酸基团后,其免疫调节活性发生了改变,这些均表明了甘薯糖蛋白的结构与其免疫调节活性有密切的关系。

A new analysis system for enrichment of glycoproteins/glycopeptides as well as the identification of glycoproteins/glycosylation sites was also established by coupling enrichment of glycopeptides by hydrazide- functionized magnetic microspheres with release of polysaccharide chains by PNGase F and mass spectrometry as well.

本实验还将肼功能化磁粒富集糖肽方法与糖肽酶酶解、生物质谱等方法相结合,建立起了一套可用于糖蛋白/糖肽分离富集并进行糖蛋白/糖基化位点鉴定的新体系。

MethodsOur study was to treat gastric ulcer by invigorating spleen and benefiting vital energy Chinese drugs through clinical observation and experimental research, and compared with mucosa protectant -gastropine and H2 receptor antagonist -famotidine about the mucosa mitochondrion 8-oxygen guanine DNA glycosylase, thymine glycol DNA glycosylase,3-methyl adenine DNA glycosylase, the effect of gastralgia, splenic asthenia and quality of ulcer recovery.

比较健中愈疡片、黏膜保护剂胃舒平以及H2受体拮抗剂法莫替丁对胃黏膜线粒体 8-氧鸟嘌呤DNA糖基化酶、胸腺嘧啶乙二醇DNA糖基化酶、3-甲基腺嘌呤DNA糖基化酶的影响,并进行健脾益气方药与黏膜保护剂胃舒平以及H2受体拮抗剂法莫替丁对胃溃疡愈合质量的比较和评价。

Such structural complexity is further enhanced by O-acetylation, esterification, lactonization, as well as other forms of substitutions, reflecting significance of carbohydrates in cell recognition.

细胞表面上糖缀合物的糖链经常以多/寡聚体形式存在,并且结构复杂,常常大量表达唾液酸、糖醛酸、硫酸化糖基等酸性糖,并发生O-乙酰化、酯化和内酯化等修饰。

Thederivatives of 5 kinds of monosaccharides Xyl, Ara, Man, Glc, Gal were detected anddetermined respectively by GC-MS. The influences of several factors, such asreductive time, reductive temperature, acetylating temperature and acetylating time,on recovery of monosaccharides were studied by orthogonal experiments. The resultsshowed that the reductive temp.

利用气相色谱—质谱联用技术检测五种常见单糖(木糖、阿拉伯糖、甘露糖、葡萄糖、半乳糖)的乙酰化产物含量,采用正交试验综合考察了还原时间、还原温度、乙酰化温度、乙酰化时间等因素对单糖回收率的影响及规律。

Objective Through observing the ei'fect of the TCM decoction TangShenHuaYuJian on the kidney weight, index of kidney hypertrophy(kidney weight/body weight), blood glucose , blood urea nitrogen, creatinine, blood advanced glycation end-products, advanced glycation end-products in kidney tissue in the earlier stage of diabetic nephropalhy rats induced by injecting 3 -cytotoxins into abdomen, to explore the relationship between nonenzymatic glycosylation and diabetic nephropathy, and provide an experimental basis for clinical application and for further studying TSHYJ.

目的 通过观察糖肾化瘀煎对长期高血糖所致的早期粮尿病肾病大鼠(腹腔注射链脲佐菌素后诱导所形成)肾重、肾重指数、血糖、血尿素氮、肌酐、血糖基化终末产物AGEs、肾组织糖基化终末产物AGEs等指标的影响,从非酶糖基化角度探讨此制剂对糖尿病肾病早期的作用机理,并为糖肾化瘀煎的临床运用和进一步开发提供实验依据。

The fine specially brewed 14° Yinpu Black Beer is produced from the brewing water of hardness, superior specially made colored malt and coking malt by means of traditional saccharification extraction after long-term fermentation in low temperature.

14°银瀑高级特酿黑啤酒,利用暂硬度较高的酿造用水,特制优良着色麦和焦香麦芽,采用传统糖化浸出法,经低温长时间发酵酿制。

Once this process is completed, the mash is heated with hops dried flowers of the female vine

一完成这个过程,我们就向糖化醪中加入啤酒花并加热,啤酒花可以防止腐败菌的生长。

The results showed that the hypoglycaemic and the urine glucose lowering effect of PCE-C in alloxan-diabetes rabbits were excellently and long-lasting. PCE-C could also reduce the serum total cholesterol and the serum triglyceride in experimental rabbits to normal level, and delay the loss of body weight of the rabbits. The glycosylated hemoglobin is the true index that reflects the long-term controlling effect for diabetes, and the experiment result affirmed the veracity and reliability of the results of the blood glucose.

结果表明,PCE-C对实验家兔血糖和尿糖的降低效果具有高效性和持续性;当血糖控制不良时,可并发血脂水平的升高,PCE-C可以使血清总胆固醇和甘油三酯恢复正常水平,同时能减缓实验家兔的体重下降;糖化血红蛋白是真正反映糖尿病长期控制效果的指标,PCE-C对实验家兔GHb的作用影响充分证实了血糖测定结果的准确性和可靠性。

Methods we experimented with: flattening the tube between a 2x4 and the sink top, the "triangle fold," mashing the tube flat with a ball-peen hammer not recommended!

方法我们试行了:平坦的管之间的2x4和洗涤槽顶端,&三角倍,&糖化管单位与球peen锤

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