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Chloroquine can ameliorate the dyslipidemia and insulin sensitivity of patients with type 2 diabetes mellitus.

氯喹能明显改善2型糖尿病患者的糖、脂代谢紊乱和胰岛素敏感性,其作用机理可能与抑制患者的胰岛素酶基因表达从而降低胰岛素降解速度有关。

Hyperuricemia is closely related with glycometabolism, lipid metabolism and hypertension, which is a risk factor responsible for occurrence and development of diabetes, hyperlipoidemia and hypertension.

高尿酸血症与糖、脂代谢、高血压关系密切,是糖尿病、高脂血症、高血压发生发展的重要危险因素。

ConclusionHyperuricemia is closely related with glycometabolism, lipid metabolism and hypertension, which is a risk factor responsible for occurrence and development of diabetes, hyperlipoidemia and hypertension.

高尿酸血症与糖、脂代谢、高血压关系密切,是糖尿病、高脂血症、高血压发生发展的重要危险因素。

Nineteen spots were changed significantly after FA treatment.Thirteen proteins were identified by peptide mass fingerprinting or peptide sequence analysis,including putative nucleoside diphosphate kinase,elongation factor 1-gamma,triosephosphate isomerase,60S acidic ribosomal protein P0,heat shock protein 75 kDa,similar to heat shock 70kD protein binding protein,annexin I,hypothetical protein FLJ34423,microtubule-actin crosslinking factor 1,lamin B2,ATP synthase alpha chain,mitochondrial precursor,proteasome subunit alpha type 6.These identified proteins involved in energy metabolism,translation and RNA processing,protein folding,redox regulation,cell structure and cell signaling.

双向凝胶电泳结果显示,甲醛刺激后19个蛋白斑点发生变化,肽指纹图谱及肽序列标签鉴定了其中13个蛋白斑点,已鉴定的蛋白包括二磷酸核苷酸激酶、延长因子1-γ,磷酸丙糖异构酶、60S酸性核糖体蛋白P0、75kDa热休克蛋白、70kD热休克蛋白样结合蛋白、钙依靠磷脂结合蛋白I、假想蛋白FLJ34423、微管-肌动蛋白交叉连接因子1、核纤层蛋白B2、ATP合成酶α链、蛋白酶体α亚基6,这些蛋白功能涉及转录调节、蛋白折叠、信号传导、能量代谢、细胞骨架等各个方面。

Thirteen proteins were identified by peptide mass fingerprinting or peptide sequence analysis,including putative nucleoside diphosphate kinase,elongation factor 1-gamma,triosephosphate isomerase,60S acidic ribosomal protein P0,heat shock protein 75 kDa,similar to heat shock 70kD protein binding protein,annexin I,hypothetical protein FLJ34423,microtubule-actin crosslinking factor 1,lamin B2,ATP synthase alpha chain,mitochondrial precursor,proteasome subunit alpha type 6.These identified proteins involved in energy metabolism,translation and RNA processing,protein folding,redox regulation,cell structure and cell signaling.

双向凝胶电泳结果显示,甲醛刺激后19个蛋白斑点发生变化,肽指纹图谱及肽序列标签鉴定了其中13个蛋白斑点,已鉴定的蛋白包括二磷酸核苷酸激酶、延长因子1-γ,磷酸丙糖异构酶、60S酸性核糖体蛋白P0、75kDa热休克蛋白、70kD热休克蛋白样结合蛋白、钙依赖磷脂结合蛋白I、假想蛋白FLJ34423、微管-肌动蛋白交叉连接因子1、核纤层蛋白B2、ATP合成酶α链、蛋白酶体α亚基6,这些蛋白功能涉及转录调节、蛋白折叠、信号传导、能量代谢、细胞骨架等各个方面。

Objective : To investigate in endocringical and metabolic characteristics on polycystic ovary syndrome with/without obesity.

目的:探讨肥胖与肥胖型多囊卵巢综合征在生殖内分泌、糖脂代谢方面的差异。

Furthermore, the triply n/i/eNOS-/- mice manifested phenotypes that resembled metabolic syndrome in humans, including visceral obesity, hypertension, hypertriglyceridemia, and impaired glucose tolerance.

此外,三重缺陷小鼠呈现出与人类代谢综合征相似的表象,包括腹型肥胖,高血压,高甘油三酯血症以及糖耐量降低。

Pioglitazone is a thiazolidinedione that ameliorates insulin resistance and improes glucose and lipid metabolism in type 2 diabetes mellitus.

吡格列酮是一种噻唑烷二酮类药物,可以改善胰岛素敏感性并且改善2型糖尿病的糖脂代谢。

Pioglitazone is a thiazolidinedione that ameliorates insulin resistance and improves glucose and lipid metabolism in type 2 diabetes mellitus.

吡格列酮是一种噻唑烷二酮类药物,可以改善胰岛素敏感性并且改善2型糖尿病的糖脂代谢。

In its biologically organic and active form - and the one used by Healthspan - this precious metal can help insulin metabolise fat, turn protein into muscle and convert sugar into energy.

在其生物有机活性形式-和使用的Healthspan -这贵重金属可以帮助胰岛素代谢脂肪,蛋白质反过来转换成肌肉,糖转化为能量。

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The split between the two groups can hardly be papered over.

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