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Results Eleven proteins, including chymotrypsinogen B1 precursor, carboxypeptidase A1, trypsinogen 2, chymotryptic peptide C, trypsin 1, carboxypeptidase B1, kinesin superfamily proteins 3B, trypsin 2, mitochondria protein gene, elastase 3A and colipase were found to be able to bind to HCV core protein. Conclusions Proteins related with metabolism of glucose and lipid may bind to HCV core protein.

因此我们应用酵母双杂交技术筛选人胰腺细胞 cDNA 文库中的 HCV 核心蛋白结合蛋白基因,为研究 HCV 慢性感染与胰岛素抵抗( insulin resistance , IR )、代谢性疾病之间的相关性及其作用机制,以及进一步研究 HCV 影响糖、脂类代谢的分子生物学机制提供一定的思路和方向。

In this study, the levels of genes and metabolite response in a heat heat-stressed thermotolerant yeast were studied.

本文从转录及物质代谢角度对热胁迫下耐热酵母中海藻糖的代谢响应进行了研究。

In the case of overcompensation, a series of physiologicalmetabolisms were improved. Plant height was decreased but LAI increased.Photosynthesis, contents of proteins, soluble sugar, starch and nitrogenmetabolism ect. showed the same trend of increase at first followed bya decrease, and then came with fluctuation close to CK.

在发生超补偿作用时,棉株体内各项生理状况都有较大改善,如株高生长受到抑制,叶面积系数增大,体内光合作用、蛋白质代谢、可溶性糖、淀粉及氮代谢等生理活动都表现出先增强而后减弱的变化趋势,然后是向CK尽量地靠近并有波动地与之保持一致。

It is also shown in this study that activation of sugar uptake and pentose phosphate metabolic pathway by xylulose made...

本文介绍了Schizosaceh.porebe的五碳糖磷酸代谢途径,这种代谢途径使得它成为用于这一目的的理想菌株。

Therefore, the metabolic pathway from soybean oil to erythromycin was presumed as follows: soybean oil is metabolized into TCA pathway to generate much α??ketoglutaric acid and then generate succinyl??

推测豆油经过红色糖多孢菌代谢后进入红霉素合成的一条可能途径:豆油经过代谢后进入TCA循环,并强化了TCA循环的通量,产生了大量α?

Therefore, the metabolic pathway from soybean oil to erythromycin was presumed as follows: soybean oil is metabolized into TCA pathway to generate much α ketoglutaric acid and then generate succinyl CoA by strengthening TCA pathway, and the methylmalonyl CoA is formed from succinyl CoA by isomerization. Finally, methylmalonyl CoA can be used as the precursor for the biosynthesis of erythromycin.

推测豆油经过红色糖多孢菌代谢后进入红霉素合成的一条可能途径:豆油经过代谢后进入TCA循环,并强化了TCA循环的通量,产生了大量α酮戊二酸,再生成琥珀酰CoA,琥珀酰CoA在甲基丙二酰CoA异构酶的作用下生成甲基丙二酰CoA作为红霉素合成的前体。

In order to explore the mechanism of 'brumal jujube' of maturation and scenescence and ethanol accumulation, We not only studied the quality and the post-harvest physiological and biochemical changes of 'brumal jujube' after treatment with hormone during storage, but also investigated the effects of CAi (C027%~10%02+ 2~5%C02) and CA2:(7%~10%02, C02 2%) on the changes of fermentation volatiles, activity of enzymes , the kind and content of sugar and organic acid during storage in this paper. Firstly announced the reason of ethanol accumulation under higher C02 level and discussed the mechanism of ethanol accumulation during the end of storage.

本研究以冬枣为试材,采后采用激素进行处理,通过对贮藏期间果实品质、生理生化指标、果实衰老相关指标和酶活性的测定,系统探讨了外源激素处理对果实采后品质及衰老的调控作用;另外对点红冬枣采用CA_1:(7%~10%O_2+2~5%CO_2)和CA_2:(7%~10%O_2、CO_2≤2%)进行气调贮藏,通过测定冬枣果实品质、乙醇发酵相关酶活性及代谢产物、糖酵解底物及参与三羧酸循环代谢的有机酸含量和种类,研究了冬枣贮藏后期乙醇积累的机制,探讨了枣果不耐高浓度CO_2贮藏的原因。

Tricarboxylic acid cycle is an important pathway to generate ATP, which is widely distributed in the cells of animal, plant or microorganism. It catalyses the catabolism of sugar as well as protein and fat.

在动物、植物、微生物细胞中普遍存在的三羧酸循环(TCA循环是产生ATP的主要途径,它不仅参与糖的分解代谢,也参与蛋白质和脂肪的分解代谢。

Our studies indicate that the increased contents of glucose and accumulation of active metabolic intermediates due to metaboic disorder contribute to the cutaneous environmental alterations associated with diabetes mellitus.Thus,the cutaneous environmental alteration is one of the initial events for impaired healing.The succession of progressive injury in deep partial thickness burn wounds is carried out depending on the physiological outcome of parabiotic tissues.The loss of dernal template due to the damage to the integrity and the continuity of dermal tissue may be one of the leading reasons of hyperplastic scar formation.

通过对糖尿病合并创面难愈、烧伤创面的进行性损害以及增生性瘢痕形成的机制研究,我们发现:糖尿病代谢紊乱所致皮肤组织中糖含量增高和代谢产物蓄积引起的皮肤微环境改变,是导致糖尿病创面难愈的始动因素之一;烧伤后的组织进行性损害的发生发展取决于&间生态&组织的病理转归;真皮组织缺损导致的模板作用缺失可能是引起增生性瘢痕形成的始动环节。

So hyperinsulinemia may step up blood pressure.These explain IR have some invariable effect in pathogenesis of eclampsism. Sex hormone binding globulin is a species of sterin haptoglobulin which is form from liver.The level of SHBG is an indirect index of balanate between androgen and estrogen.Not only hyperinsulinemia but also IR have intimate relationship with blood serum SHBG level.

高胰岛素血症、胰岛素抵抗与血清SHBG水平均有着密切关系,胰岛素对调节SHBG的代谢具有重要意义,胰岛素水平升高使SHBG生成减少,造成体内性激素水平紊乱,导致糖、脂肪、胰岛素代谢障碍,提示SHBG是高胰岛素血症、胰岛素抵抗的一个特有标志。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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