糊精

The fluorescence anisotropy using steady-state fluorescence polarization method was measured for the solution of β-CD and cinchonine mixed and sonicated for 1h. The anisotropy values for the solution increased with the increase of the concentrations of β-CD, which implied the existence of some complexes of large size or nanotube structure. Many type of large size complexes formed between β-CD and Cin under high concentrations in gas phase were characterized by ESI-MS in moderate experiment conditions.

将辛可宁与环糊精的混合溶液超声1个小时后，用稳态荧光偏振方法测定溶液的各向异性值，发现随着环糊精浓度的增大，溶液的荧光各向异性不断增强，这意味着溶液中形成了大尺寸即纳米级结构的环糊精与辛可宁复合物；用温和的质谱测定条件表征发现高浓度的β-CD与辛可宁在气相中可形成各种类型的大尺寸复合物。

The optimum technological conditions has been obtained as follow: under the conditions of liquefaction temperature 105℃, enzyme decompound temperature 92℃, addition of 0.1~0.2 g/kg (20000 U), hydrolysis time 40~50 min, concentration of substrate 15%~20%, maltodextrin production DE can less than 7.0. The content of keeping transparence has been studied, provided a strong foundation to industry production.

通过正交实验，确定了生产低DE值麦芽糊精的最佳工艺条件为：液化温度105℃，酶解温度92℃，酶用量0.1~0.2g/kg干物，酶解时间40~50 min，淀粉浆质量分数15%~20%，麦芽糊精的DE值达到7.0以下，并对低DE值麦芽糊精保持透明度提出了组分要求和最高浓度要求，为其工业化生产打下了坚实的基础。

As the secondary generation host, CD have received considerable attention because of its particular characterization, and the studies on host-guest interaction based on CD had been transferred from the processes and mechanism of inclusion complex between a pair of host and guest to construction of functional supramolecular aggregates, then these will be useful in the design and preparation of molecular machine and molecular devices, such as molecular pinchers, molecular gears, molecular motors and molecular balances, etc.

它的发展也先后经历了冠醚、环糊精、杯芳烃三代主要的主体化合物，环糊精作为超分子化学的第二代主体化合物以其独特的性质而倍受关注，基于环糊精的主-客体相互作用也在研究单一主体与客体包结形成过程及形成机理的基础上，进而追求具有特定功能的超分子聚集体，为设计制备分子钳、分子齿轮、分子马达、分子秤等重要分子器件和分子机器奠定基础。

A novel β-cyclodextrin graft copolymer was synthesized by immobilizing β-CD onto the linear chain of PVA through acetalization reaction.

利用缩醛化反应将醛基化β环糊精固载到聚乙烯醇大分子链上，合成出了聚乙烯醇固载β环糊精的线性环糊精高分子，其最佳反应条件是反应时间 2h ，温度 70℃，β CD 6 CHO与PVA的质量比小于等于 4∶1。

METHODS: Mono-6-O-tosyl-β-CD and mono-6-formyl-β-CD were synthesized separately. Silylatedβ-CD was loaded onto polymer chain of PVA by acetalization to produce PVA containingβ-CD linear high polymer.

分别合成单6-对甲基苯磺酰β-环糊精酯和单6-甲酰基β-环糊精，利用缩醛化反应将醛基化β-环糊精固载到聚乙烯醇大分子链上，合成出聚乙烯醇固载β-环糊精的线性环糊精高分子。

Two kinds of polymer-β-cyclodextrin derivatives(PCM-β-CD and PAE-β-CD) with different substition degrees and crosslinked densitiese were synthesized by using epoxychloropropane and Carboxymethyl-β-Cyclodextrin and N-(2- aminoethyl) amidine-β-Cyclodextrin of retaining the amino with different substitution degrees crosslinking polymerization.

论文对含有羧基和氨基的两类β-环糊精聚合物即聚合羧甲基-β-环糊精及聚合N-(2-氨乙基)胺基β-环糊精的合成及其吸附有机污染物碱性品红和苯酚的性能进行了以下研究。1。

The features of AAA adsorbed on the ethylatedβ-CD polymer were similar with those of the parentalβ-CD polymer, but theadsorption ratios of AAA on the ethylatedβ-CD polymer were higher than those of the parentalβ-CD polymer. It may be due to the strengthened hydrophobic interactions between AAA and the ethylatedβ-CD polymer, which was caused by the ethylation of the parentalβ-CD polymer.

研究表明其对芳香氨基酸的吸附规律与母体β-环糊精聚合物类似；与母体β-环糊精聚合物相比，芳香氨基酸在该聚合物上的吸附率有所增加，这可能是因为乙基化增强了β-环糊精空腔外沿的疏水性，从而增强了乙基化β-环糊精聚合物与芳香氨基酸之间的疏水相互作用。

The results showed that the reaction activity between glycinin (7S subunit) and maltodextrin was high, and the reaction proceeds quantitatively regardless of the variation of protein and polysaccharide mass ratio. The molecular properties of the formed conjugates are also highly uniform. The reaction activity between β-conglycinin (11S subunit) and maltodextrin is relatively lower Compared to that of glycinin, and the molecular properties of these conjugates are affected by the variation of the R values.

电泳分析表明：7S亚基与麦芽糊精的反应性较高，而且在文中所研究的蛋白质与多糖质量比的范围内，7S亚基都能与麦芽糊精发生定量的共聚合反应，形成分子特性高度一致的共聚物；而11S亚基与麦芽糊精间的反应性较低，共聚物的分子特性受蛋白质与多糖质量比的影响。

Respectively, glutamic acid derivatized β-CD has been synthesized with epoxy chloropropane as the intermediate, a water-insoluble yellow liquid was got after the acetylating of the by using acetic anhydride, which was used as a novel gas chromatographic CSP; A water-soluble β-CD polymer cross-linked with epoxy chloropropane has been synthesized, and the derivatives of β-CD polymer were synthesized by its alkylating and acetylating. The different β-CD derivatives were coated on silica capillary columns by dynamic method, the chromatographic properties and retention behaviors of the fused silica capillary columns were studied, the results showed that the β-CD derivatives had good stereoselectivity and separation results to some compounds, especially to various positional isomers and enantiomers.

本文还分别以环氧氯丙烷为中间体，合成了七{2，6-二-O-[3-(1，3-二羟基丙氨酸)]}-β-环糊精，再用醋酸酐将其乙酰化，得到了一种淡黄色粘稠液体，合成了一种新型的环糊精衍生物；以环氧氯丙烷作交联剂合成了一种水溶性的β-环糊精聚合物，再将其烷基化和酰基化，合成了β-环糊精聚合物的不同衍生物，用动态法将不同类型的β-环糊精衍生物涂渍在石英毛细管柱上，通过对所制备柱柱性能的测试和对一系列化合物的分离和保留行为的研究，结果表明所合成的β-环糊精衍生物对各类化合物，特别是对位置异构体和对映异构体具有较好的分离效果，显示了很强的立体选择性。

Based on the changes in the spectrum characters of guest molecules producedthrough inclusion complex formation with cyclodextrins, we have carried out two aspects of investigation:First, the mechanisms for the host-guest recognition reactions have been studied, such as the interactions between 3-CD and curcumin, the main constituent of the rhizomes of the plant Curcuma longa, the recognition of p-CD towards rubidate, the effective component of the Chinese traditional medicine madder, and the reactions of p-CD towards the antileprotic drug dapsone and the antiinflammatory drug nabumetone: The formation of supramolecular complex between P-CD and guest molecule has been discussed and verified in virtue of multitudinous means such asultraviolet-visible absorption, fluorescence emission, infrared spectrogram and so on. The influence of addition of linear alcohols on the supramolecular system has been studied and the reason why the noncovalent interactions in the three-component system could result in a decrease in the apparent association constant of the inclusion complex has been revealed.

本论文基于环糊精对被包结客体光谱性质的改变，开展了两大方面的研究：β-环糊精对姜黄属植物根茎主要成分—姜黄素、中药茜草有效成分—茜草双酯、抗麻风药物氨苯砜及抗炎药物萘丁美酮的主-客体识别反应机制研究：借助超分子包合物的紫外吸收光谱、荧光光谱或红外吸收光谱等手段，通过多种方法探讨并验证了超分子包合物的形成；研究了直链醇的加入对超分子体系的影响，揭示了三元体系中非共价相互作用导致超分子包合物表观结合常数降低的原因：对超分子包结反应进行了热动力学研究，探讨了各热动力学参数的变化趋势并从熵焓互补的角度考察了超分子包结过程；通过荧光猝灭实验进一步揭示了水相中β-环糊精增敏客体荧光的本质原因，从而为超分子化学提供新的理论和研究方法。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失