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objective:aripiprazole in the treatment of schizophrenia with diabetes caused by antipsychotic drugs of the safety study.

目的:评估阿立哌唑在抗精神病药物所致的糖尿病精神分裂症治疗中的风险。

Forty-six schizophrenic patients,who were first-episodic and never administered neuroleptic agents,were assessed with EPS by the extrapyramidal symptom rating scale and evaluated with clinical symptoms by the positive and negative symptom scale before and after treatment.

以锥体外系症状评定量表对46例首次发作、从未应用抗精神病药物治疗的精神分裂症患者,在应用利培酮治疗的前、中、后进行检查。结果:有6例(13.0%)患者在治疗前就存在明显的EPS,但在利培酮治疗后都未出现EPS。

objective to know the affection and related factors of neuroleptic to myocardial ischemia.methods i make a questionnaire by myself and investigate the electrocardiograms of 358 mental patients in our hospital.results myocardial ischemia is more familiar and it is reated to sex and age.conclusion the side effect of neuroleptic to heart cannot be neglected and electrocardiogram shall be inspected termly when neurolepthic is used, especially for female patients.

目的 了解抗精神病药物对心肌缺血(s-t段下移、t波低平、倒置)的影响及相关因素。方法自行设计调查表,对我院358例住院治疗的精神病患者进行心电图调查。结果心电图改变以心肌缺血较常见,且与性别、年龄相关。结论抗精神病药物对心脏的副作用不可忽视,应用抗精神病药物时定期监测心电图,尤其是女性患者。

Methods Serum prolactin levels were meaured and analyzed in 80 schizophrenics taking different antipsychotics before and after treatment.

对80例女性精神分裂症患者服用不同抗精神病药物治疗前后的血清催乳素水平进行测评分析。

It is a leading publication in psychopharmacology offering a wide range of articles reporting on clinical trials and studies,side effects,drug interactions,overdose management, pharmacogenetics,pharmacokinetics,and psychiatric effects of non-psychiatric drugs.

这是一份在精神药理学领域的领头刊物,它刊登文章的范围很广,包括临床试验和研究、副作用、药物相互作用、过量管理、遗传药理学、药物动力学以及非治疗精神病药物的精神病治疗效果等。

ResultsThe similarity, digit span, digit sign, picture, picture remembrance , vision renew in patients after treatment were higher than those before treatment ( P .05). As to the total number, total error number and persistent error number of WCST (P . 05).DiscussionIn this study, thirty - five patients who took Risperdal treatment have cognitive function disorder in different disagree, after 12 weeks, nine items among twelve items reflecting cognitive function have significant difference , indicate cognitive deficits in schizophrenia are reversible and related to new type antipsychotic drug .

实验结果 35例患者在服用利培酮治疗前和治疗12周后认知功能的测验的比较,在相似性、数字广度、数字符号、填图、图片回忆、视觉再生测验中有显著性差异(P<O.05L在*qT中,总测验数、总错误数、持续错误数均有显著性差异沙<o.05人讨论本研究中35例病人应用利培酮治疗前均有程度不同的认知功能损害,经12周治疗后,反映认知功能的十二项分测验中的九项均与治疗前呈显著性差异,提示精神分裂症的认知功能损害具有可逆性,且与新型抗精神病药物密切相关。

Refractory schizophrenia. Methods 60 TRS patients on antipsychotics were added to MECT for 12 weeks.

对60例难治性精神分裂症患者在原服用抗精神病药物治疗的基础上联合无抽搐电休克治疗,观察12 w。

And switching criteria was following:(1) manic or hypomanic episode; or(2) promoting rapid cycling; or (3) YMRS≥11 or irritability or aggravation in YMRS ≥3.(4) Psychiatrist think that the patients should be stopped to take antidepressants and should be placed by mood stabilizer or antipsychotics or their combination.

其中转相标准是:(1)出现躁狂或轻躁狂;或者(2)原来的循环加快;或者(3)杨氏躁狂评定量表≥11分或者其中的易激惹和破坏攻击行为≥3分;(4)治疗医师认为应该停用抗抑郁药物而使用抗精神病药物或心境稳定剂。

RESULTS:Advance in synthetise of the second-generation antipsychotic drugs has been swiftly in rencent years,it improve the recognizing ablity of patients with schizophrenia,it has good safety and tolerance,is still the efficient and first choice drug for the treatment of patients with psychotic and schizophrenia.

结果:抗精神病药的合成进展迅速,第二代抗精神病药在整体上能改善精神病者的认知功能,安全性和耐受性好,成为治疗精神分裂症和精神病有效的首选药物。

Spirit medicaments treats medium action in mental disease 1 spirit of 1 · medicaments is to point to the mental activity that can improve morbid state, do not affect the medicaments of normal spirit activity again.

在精神病医院开展精神药物药学服务,顺应了医生、护士和患者的要求,保证了精神病患者药物治疗的效果。1精神药物在精神疾病治疗中的功能1·1精神药物是指能改善病态的精神活动,又不影响正常精神活动的药物。

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