精神分裂症

The deficit in sleep spindles in schizophrenia subjects may reflect dysfunction in thalamic-reticular and thalamocortical mechanisms and could represent a biological marker of illness.

精神分裂症患者的睡眠纺锤波异常反映了皮质－丘脑和丘脑－皮质机制的功能障碍，有可能成为该疾病的生物学指标。活动结束了？

Results The onset of depression was mainly influenced by life events, although depressive mood was accompanied by schizophrenialike symptoms, suicide idea and behavior as well as retardation of thought were more outstanding; although PSD exhibited depressive emotions, yet more patients had hallucination and delusion content which was unconsistent to depressive emotions.

结果 抑郁症起病多受生活事件的影响，抑郁心境伴精神病性症状时，自杀意念和行为及思维迟缓等症状较为突出；精神分裂症后抑郁虽表现有抑郁情绪，但仍有较多患者有与抑郁情绪不相适应的幻觉、妄想性内容。

The delusion of schizophrenics might be related with unmature defense mechanisms.

精神分裂症的妄想可能与较多应用不成熟防御机制尤其是投射、潜意显现、抱怨、分裂等有关。

Methods: Two tag SNPs (rs2439322 and rs16879809) of NRG-1 in 254 schizophrenia trios were genotyped by using PCR-RFLP, and LD, TDT and HHRR were analyzed by using EMLD, UNPHASED and TRANSMIT softwares.

目的 ：探索位于 8 号染色体短臂（ 8p ）的神经胶质细胞生子因子 1 （ NRG-1 ）基因与精神分裂症易感性之间的关系；探索同样位于 8p 的 NRG-1 基因与 ASAH1 基因之间的相互作用。

Methods : Two tag SNPs (rs2439322 and rs16879809) of NRG-1 in 254 schizophrenia trios were genotyped by using PCR-RFLP, and LD, TDT and HHRR were analyzed by using EMLD, UNPHASED and TRANSMIT softwares.

应用 PCR-RFLP 检测 254 个精神分裂症核心家系 NRG-1 基因上的 2 个标签 SNPs （ rs2439322 和 rs16879809 ），进行 LD 、 TDT 、 HHRR 及单体型 TDT 分析。

Three SNPs (rs3753118, rs3753116 and rs7830490) of ASAH1 in 254 schizophrenia trios were genotyped by using PCR-RFLP, and the LD, TDT and haplotype TDT were analyzed by using EMLD, UNPHASED and TRANSMIT softwares.

应用聚合酶链反应和限制性片段长度多态性技术对254个精神分裂症核心家系ASAH1基因的3个SNPs（rs3753118、rs3753116和rs7830490）进行检测，计算LD、TDT及单体型TDT。

Three SNPs (rs3753118, rs3753116 and rs7830490) of ASAH1 in 254 schizophrenia trios were genotyped by using PCR-RFLP, and the LD, TDT and haplotype TDT were analyzed by using EMLD, UNPHASED and TRANSMIT softwares.

应用聚合酶链反应和限制性片段长度多态性技术对254个精神分裂症核心家系ASAH1基因上的3个SNPs（rs3753118、rs3753116和rs7830490）进行检测，计算连锁不平衡、传递不平衡及单体型TDT。

A glance at that dark, unstitched wound and a deep fissure in my brain opens up: all the images and memories that had been laboriously or absent mindedly assorted, labeled, documented, filed, sealed and stamped break forth pell mell like ants pouring out of a crack in the sidewalk; the world ceases to revolve, time stops, the very nexus of my dreams is broken and dissolved and my guts spill out in a grand schizophrenic rush, an evacuation that leaves me face to face with the Absolute.

所有以前费力地或心不在焉地分门别类、贴标签、引证、归档、密封并且打上印戳的印象和记忆乱纷纷一涌而出，就像一群蚂蚁从人行道上的一个蚁穴中涌出。这时地球停转了，时间停滞了，我的梦之间的相互联系也断了、消逝了，在精神分裂症大发作中我的肚肠流出来，这一次大扫除后我就与上帝面对面站在一起了。

The qualitative and quantitative analysis of schizophrenia and single nucleotide polymorphism of catechol-O-methyltransferase , Proline Dehydrogenase and DYSBINDIN genes were done by using transmission disequilibrium test . Results:(1) The symptoms of first-episode schizophrenia were divided into four independent symptom dimensions: psychomotor poverty, reality distortion, disorganisation and depression-anxiety.

4采用传递不平衡检验、单倍型传递不平衡检验和定量性状传递不平衡检验的方法对6号、22号染色体上3个候选基因，即儿茶酚氧位甲基转移酶(catechol-O-methyltransferase，COMT)、脯氨酸脱氢酶(Proline Dehydrogenase，PRODH)和DYSBINDIN基因的9个单核苷酸多态性(single nucleotide polymorphism，SNP)位点与精神分裂症、神经认知功能、人格特质和临床症状表现的关系进行了定性和定量的遗传学分析。

The results provide further evidence to support that DAOA gene locus is involved in conferring susceptibility to schizophrenia.

总之，我们的研究进一步支持了DAOA基因座位对精神分裂症的高度易感。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。