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精神分裂症

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These results suggest that (1) schizophrenic patients could exhibit impairments of interhemispheric coO p e r ation,(2)especially for more complex task processing;(3) their cerebral functional lateralization deficit may be a lack of coO p e r ation between the hemisphere.

(1)精神分裂症患者两半球协同功能异常;(2)在任务难度较高的条件下表现较为明显;(3)精神分裂症患者认知加工中的脑功能一侧化异常可能与两半球间注意与加工资源配置和调节异常有关。

The main approaches used to identify susceptibility genes are linkage and association studies and schizophrenia is found to be a polygenic disease rather than a monogenic disease, which is influenced by multiple genes with minor or medium risks, and environment factors as well.

目前鉴定精神分裂症易感基因最主要的方法是连锁分析、关联分析,人们发现精神分裂症并不是单基因遗传病,而可能是多个微效或中效基因共同作用的多基因疾病,并且还受到环境因素的很大影响。

OLIG2 is a transcription factor which could regulate the transcription of many oligodendrocyte/myelination related genes, and its expression level also was down-regulated in schizophrenia subjects. Therefore, OLIG2 is mostly like to be a risk gene of schizophrenia.

OLIG2是一个能够调控下游许多与少突触细胞/髓鞘发生相关的基因表达的转录因子,且OLIG2的表达水平在精神分裂症患者体内也明显下降,因此,OLIG2极有可能是精神分裂症的致病基因。

Results Age is an important factor influencing HCT performance;of subtypes of schizophrenia only organic schizophrenia was significantly related to the HCT;showed significant relation with the HCT. Among the AMDP symptoms, perceptibility was negatively related to HCT, selfhallucination and derealization positively to.

结果 年龄是影响哈氏分类测验的重要因素;各精神分裂症类型中只有器质性精神分裂症与哈氏分类测验有显著相关;在AMDP的症状中,知觉能力与哈氏分类测验呈负相关,自我幻觉和现实感丧失与哈氏分类测验呈正相关。

The experiment preliminarily validated genetic characteristics of schizophrenia, cumulative effect of polygene, genetic heterogeneously and clinical heterogeneously.

本实验初步验证,精神分裂症的遗传特点即多基因累积效应、遗传异质性和临床异质性,为精神分裂症遗传机制的研究奠定了理论基础。

The serum prolactin levels were measured in 11 depressed patients, as compared with those of 20 normal subjects and 20 schizophrenics.

本文报道11例抑郁症患者的血清催乳素的测定,并以正常人20名及精神分裂症患者20例作为对照组,发现精神分裂症及抑郁症患者的血清PRL均较正常人为高。

Objective:To compare efficacy and adverse effects of Aripiprazole and Risperidone in the treatment of first episode Schizophrenia Methods:60 cases of Schizophrenia as per CCMD-3 criteria were enrolled and treated. Blood protraction and tasting blood glucose were tested at baseline and 8 weeks after treatment.

目的:以利培酮对照,探讨阿立哌唑治疗首发精神分裂症疗效和不良反应方法:将符合CCMD-3精神分裂症诊断标准的60例患者随机分为阿立哌唑组和利培酮组进行治疗,分别在治疗0、2、4、8周末评定PANSS和TESS量表,在0、4、8周末检查心、脑电图和肝、肾功能。

Objective:To compare the response control and attention of Schizophrenic patients with that of the healthy controls by Integrated Visual and Auditorycontinuous performance test. To quantitate the impairment of cognitive function in patients, and to explore the relationship between cognitive function and the severity of the disorder.

目的:探讨精神分裂症病人在IVA持续操作测试中的反应控制能力、注意力等,并与健康人进行比较,从而量化精神分裂症病人的认知功能损害,并进一步探讨其认知功能与疾病严重程度的关系。

Some neurotransmitter changeduo obvion- dly rhythmically, cppeared the phenomenon that the rhythm was dirocder, which shwed. the body's regnlaty capability of schizo- phreniac be weakened, couednt synchronize the change rhythm of Yin and Yang, and It gave a proof to the hypothesis that there is central neurotransmitter metabolism disorder about schizophre- niac.

部分递质的含量一年四季呈节律紊乱现象,提示精神分裂症患者机体的调节能力减弱,不能与四时阴阳消长变化的节律相同步,也支持了精神分裂症中枢神经递质代谢紊乱的假说。

Objective: To explore the effect of risperidone or chlorpromazine on the serum interleukin-8 (IL-8) and inferon-γ levels in chronic schizophrene , and the change of immune function in chronic schizophrene .

目的:了解利培酮、氯丙嗪治疗对慢性精神分裂症患者血清白细胞介素-8(IL-8)、干扰素-γ水平的影响,以探讨慢性精神分裂症患者免疫功能的变化。

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