精神分裂症

The purpose of this study was to investigate the relationship between immune variables and psychopathology in patients with chronic schizophrenia before and after neuroleptic treatment, to evaluate the effect of neuroleptic on the immune parameters and the correlation between changes of immune variables and therapeutic effectiveness.

为探讨精神分裂症精神病理与免疫指标的相关性、评估抗精神病药对免疫指标的影响及其与疗效的关系，用固定剂量氟哌啶醇治疗50例慢性精神分裂症患者12周，在治疗前后测查T细胞亚群和白细胞介素2（IL－2）分泌细胞，并采用简明精神病评定量表、阳性症状评定量表和阴性症状评定量表进行评定。

The T; LH and FSH level of serum of male schizophrenia were lower than that of normal control, but the PRL level of serum of male were significant higher than that of normal control, f There wsa a significant relationship between psychiatric symptoms and sex hormones level. There was a positive correlation between extreme and pugnacity factor of PANSS and T level of serum in male schizophrenic patients, There was a negative correlation between psychopathological scores and 〓level of serum in female schizophrenic patients, g There was a significant correlation between neuropsychological tests scores and sex hormones level of serum. There was a significant positive correlation between cognitive function and T level of serum in male schizophrenic patients. There was a significant positive correlation between cognitive function and 〓 in female schizophrenic patients.

治疗后病人的PRL较治疗前有显著提高；6）精神分裂症病人的精神症状与其性激素水平的相关有统计学意义，其中男性病人的T与PANSS中的偏激/好斗呈正相关，女性病人的〓与PANSS中的一般精神病理量表分呈负相关；7）精神分裂症病人的认知功能与其性激素水平的相关有统计学意义，男性病人的神经心理测验成绩与T呈正相关，女性病人的神经心理测验成绩与〓呈正相关。

Looking after the schizophrene was a ridden job. There was not a significant difference on psychological burden of schizophrenic caregiver among the three groups.

照料精神分裂症患者，是一项心理、生理备受折磨的工作，住院精神分裂症患者照料者精神负担在不同医院之间无明显差异。

Dr. Harrison pointed out that the concern about adherence has ramifications beyond schizophrenia."Approximately 20% to 30% of patients don't refill prescriptions of any type, whether they're antipsychotics or statins," he said. In schizophrenia, the investigators reported, the issue of nonadherence is more widespread and the consequences more dire: 40% to 50% of patients with schizophrenia do not adhere to their prescribed medications and are therefore at risk for exacerbation of psychosis and rehospitalization.

Harrison医师指出，关于服药顺从性的忧虑是精神分裂疾病的副产物，大约20%至30%的病患不会再回来领药，不论是何种形式的药物，抗精神分裂药物或是statins类药物；以精神分裂症来说，顺从性不佳的情况更是普遍，而且后果更是可怕，将近有40%至50%的精神分裂症病患并不会按时服药，因此是精神病发与住院的高危险群。

Dr. Harrison pointed out that the concern about adherence has ramifications beyond schizophrenia."Approximately 20% to 30% of patients don't refill prescriptions of any type, whether they're antipsychotics or statins," he said. In schizophrenia, the investigators reported, the issue of nonadherence is more widespread and the consequences more dire: 40% to 50% of patients with schizophrenia do not adhere to their prescribed medications and are therefore at risk for exacerbation of psychosis and rehospitalization.

Harrison医师指出，关於服药顺从性的忧虑是精神分裂疾病的副产物，大约20%至30%的病患不会再回来领药，不论是何种形式的药物，抗精神分裂药物或是statins类药物；以精神分裂症来说，顺从性不佳的情况更是普遍，而且后果更是可怕，将近有40%至50%的精神分裂症病患并不会按时服药，因此是精神病发与住院的高危险群。

In order to compare the computed tomography scan of schizophrenia and bipolar disorder, 27 bipolar patients and 25 schizophrenic patients who met criteria of International Classification of Diseases, the 10th version and Chinese Classification and Diagnostic Criteria of Mental Diseases, 2nd revised edition were evaluated by computed tomography, using quantitative measures of ventricular size, and sulcal prominence.

为了比较双相情感性精神障碍、精神分裂症病人脑结构的变化，收集符合国际疾病分类第10版和中国精神疾病分类方案与诊断标准第2版修订本的双相情感性精神障碍病人27例，以及精神分裂症病人25例，应用脑CT定量分析脑室、脑沟。

Objective:To explore the relationship of negative schizophrenic cognitive function improvement with HVA and 5-HIAA, Method:Thirteen negative schizophrenic patients were treated with clozapine for 8 weeks,Memory,attention,executive function were assessed separately with Waise memory scale,cancellation test and Wisconsin card sorting test before and after treatment,and cerebrospinal fluid HVA and 5-HIAA levels were determined with HPLC-ECD, Results:Part of short memory was improving with decreasing of HVA or increasing of 5-HIAA,while significant correlation were not found between improvement of memory quotient,attention,executive function and change of HVA,5-HIAA, Conclusion:The great part of negative schizophrenic cognitive function improvement has marked correlation with change of DA and 5-HT

目的：探讨阴性精神分裂症认知功能的改善与HVA和5-HIAA变化的关系。方法：对13例阴性精神分裂症在氯氮平治疗前和治疗8周后分别采用韦氏成人记忆量表，数字划消测验和威斯康星卡片分类测验(Wisconsin card sorting test，WCST)评估其记忆、注意及执行功能，采用高效液相色谱-电化学检测测定其治疗前和治疗后脑脊液中DA代谢产物高香草酸和5-HT代谢产物五羟吲哚乙酸(5-HIAA)的浓度。结果：部分短时记忆随HVA降低或5-HIAA的增高而改善。而总的记忆商数，注意及执行功能的改善与HVA和5-HIAA的变化无明显相关。结论：大部分阴性精神分裂症认知功能的改善与DA和5-HT浓度变化无明显相关。

Schizophrenic CSF can result in significant pathologically ultrastructural changes of neurons and cerebral capillaries of macaque' brain. CSF of patients with brain atrophy can produce more serious pathological changes than CSF of patients without that. Abnormal microvessel milieus may probably contribute the neuron pathological changes and play an important role in biological mechanism of schizophrenia.

（ 1 ）精神分裂症病人脑脊液可导致食蟹猴大脑神经元超微结构发生明显病理改变，脑结构异常者的影响更为明显和严重；（ 2 ）精神分裂症病人脑脊液可造成食蟹猴大脑毛细血管超微结构发生血管周围水肿和内皮细胞病变等病理改变；（ 3 ）微血管环境异常可能在精神分裂症病理机制中具有重要作用。

Methods By using SCL90, the parents of 36 children with schizophrenia were studiedResults The parents＇ mental health (including personal relations, depression, anxiety, paranoea, somatization, hostility and fear) was worse than the normal model (P01 or P05) The mean scores of somatization, depression and anxiety of the children's mother was significantly difference from those of their father (all P05) The average score of personal relation factor in mother was obviously lower than in father Conclusion Clinical medical and nursing staff should pay attention to the mental health of the diseased children's parents and provide corresponding mental interventional measures

目的 探讨精神分裂症患儿父母心理健康状况。方法采用SCL90 对36例精神分裂症患儿父母进行调查。结果患儿父母整体心理健康状况较常模差，其中人际关系、抑郁、焦虑及偏执4项因子分与常模比较，差异有极显著性意义（均P01）；躯体化、敌对和恐怖3项因子分与常模比较，差异有显著性意义（均P05）。患儿母亲躯体化、抑郁、焦虑3项因子分均明显高于父亲，两者比较，差异有显著性意义（均P05）；而人际关系因子分明显低于父亲。结论临床医护人员应重视精神分裂症患儿父母的心理健康状况，并给予相应的心理干预措施。

Methods Using selfmade investigating table, the data of 30 patients with schizophrenia complicated by diabetes mellitus and 30 patients simple schizophrenia were collected and analyzed.

目的 探讨精神分裂症合并糖尿病患者的临床特征。方法使用自制调查表，收集30例精神分裂症合并糖尿病患者和30例单纯精神分裂症患者。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。