精子中心

A single centriole appears at the late stage of spermatid.

晚期精细胞中出现单个中心粒，但在成熟精子中消失。

In addition, spermiogenesis includes chromatin condensation, migration of the cytoplasm and mitochondria to the caudal pole of the nucleus, formation of a moderate axial nuclear fossa containing the proximal centriole and part of the distal centriole and presence of a short cytoplasmic canal separating mitochondria from the flagellum.

另外，精子发生过程中还包括染色质浓缩，细胞质和线粒体向细胞核的尾端迁移，在核的后端中轴位置上形成中等大小的核后凹，近端中心粒和远端中心粒的一部分嵌在核后凹之内，短的胞质内陷管将线粒体与鞭毛分隔开。

In the process of spermiogenesis, the proximal and distal centrioles translocate to the rear of the spermatid nucleus where the proximal centriole is attached, while the distal centriole elaborates the flagellum. The fluorescent centrin protein was seen to be located in basal body of flagellum. But the fluorescent spots could not be detected in the epididymal mature spermatozoa.

在精子变态分化过程中，近端和远端中心粒向核后方移动，近端中心粒附在核后膜上，远端中心粒伸出鞭毛，荧光显示Centrin蛋白位于伸出鞭毛的基部，但在成熟精子中该蛋白消失。

Spermatozoa of Hemicentrotus pulcherrimus belong to the type of flagelloform, it has a coniform cell nucleus on its head, a small apical body on its forepart, four mitochondria, a couple of central granules, and a flagellum.

海胆精子与其他无脊椎动物的精子一样，属于鞭毛型，其头部包含一个圆锥形的细胞核，前端配有一个小的顶体，还包括4个线粒体、一对中心粒和一根鞭毛。

In human spermatozoa, the positive immunofluorescent staining of centrin protein was seen to be located in the basal body of flagellum and clearly in proximal and distal centrioles.

健康男性精子中Centrin免疫荧光阳性，位于鞭毛的基体部，显示近端和远端中心粒，而Cenexin只在一个中心粒上有明显阳性染色，表明该蛋白是人成熟精子中心体的一种重要结构成分。这一结果显示了人和啮齿目动物精子中心体的差异。

Results In the medium and high dose F0 groups, it was observed that the atrophy and incrassation of seminiferous tubule, decrease of spermatogenesis, hyperplasia of interstitial tissue, especially in high dose groups spermatozoon abnormality and nucleolus concentration in the rats testis after DU ingestion for 14 months. The changes became more severe with the prolongation of DU ingestion. Such changes occurred in filial rats (F1) after DC ingestion for 5 months. In the medium and high dose F0 groups, it was observed that a little atrophy of kidney glomerulus, hyperplasia of interstitial tissue after DC ingestion for 14 months, and kidney glomerulus fibrosis happened after DC ingestion for 20 months, such changes occurred in filial rats (F1) after DC ingestion for 5 months In the medium and high dose F0 groups, splenic germinal center and periarterial lymphatic sheaths were hyperplasia , companies with lymphopoiesis after DC ingestion for 7 months, splenic white pulp became more small and sparse after DC ingestion for 20 months.

结果 F0代的中、高剂量组大鼠摄入贫铀14个月后可见雄性的精曲小管萎缩，管壁增厚呈空虚网状，生精细胞层次减少，间质细胞增生，但仍见有精子生成；高剂量组可见到精子呈异型性改变，细胞核浓缩深染，且随着摄入时间延长改变愈趋明显；F1代大鼠摄入贫铀5个月后就有上述改变且更为严重。F0代中、高剂量组大鼠摄入贫铀14个月后肾小球轻度萎缩，间质增生明显，20个月时肾小球萎缩纤维化；F1代大鼠摄入贫铀5个月后就有上述改变。F0代中、高剂量组摄入贫铀7个月时脾脏生发中心和淋巴鞘增生，淋巴母细胞增生活跃，20个月时脾小体减少，生发中心稀疏；F1代大鼠摄入贫铀早期和晚期有类似改变。F0和F1代高剂量组摄入贫铀早期肝脏有炎症细胞浸润，晚期骨髓有核细胞减少，脂肪细胞增加。

These data suggested that the centrin isoforms played different roles in different stages of spermatogenesis. The centrin-1 gene was revealed to be relevant to the centriolar translocation to the posterior pole of cell and the elaboration of flagellum during spermiogenesis, while the centrin-2 and centrin-3 might play roles in spermatogonial mitosis but were not involved in the spermatid differentiation process.

这些结果提示，Centrin同源基因在精子发生的不同阶段发挥不同功能，其中Centrin-1与精子细胞分化期的中心体后移、鞭毛的生成及精子中轴形成可能密切相关，Centrin-2和-3则可能在精原细胞有丝分裂中起作用，而与精子细胞变态分化无关。

We think that centrin play an important role in meiosis during Urechis unicinctus sperm metamorphosis difference and we also think that centrin may be related to trochophore cilia and sperm tail formation,and reconstraction of centrosome after fertilization.

我们推测Centrin在单环刺螠精子发生过程中减数分裂或精子细胞变态分化过程中发挥作用；在单环刺螠早期胚胎发育中，Centrin可能与受精后中心体的重建及担轮幼虫的纤毛形成有关。

Data and method 1 ～ will be in 1.1 clinical data in December 2007 couple of this central travel IVF-ET 4, patient 1, 2, 3 pathogenies all send a gender for afterwards infecund disease, tubal block, 4 pathogenies are the patient to send a gender formerly infecund disease, oviduct is connected and not disease of free, weak spermatozoon.

然而，部分患者在取卵日因为精神过度紧张出现取精困难，经心理疏导、药物治疗后多次手淫取精、夫妻性交中断法取精等处理后均失败，部分生殖中心有时通过电子射精仪取精，而大部分中心则需通过穿刺取附睾或睾丸精子来进行卵细胞胞质内单精子注射完成体外受精。

While the positive immunofluorescent staining of cenexin could only be seen in one of the centrioles, suggesting that the cenexin protein might be a special component of human matured sperm centrosome.

值得注意的是，利用抗Centrin多克隆抗体对18例男性不育病人精子的免疫荧光观察发现一些精子中Centrin蛋白的分布异常，主要表现为Centrin弥散，未显示正常大小的近端和远端中心粒。提示中心体蛋白异常是否为引致某些男性不育症的因素之一，值得进一步研究。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。