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The essential events of the process are detachment, intravasation, circulation, arrest, extravasation, angiogenesis and proliferation, which come down to interactions of neoplastic cells with host cells and extracellular matrix -governed by adhesion, migration, invasion, proteaselysis, and the complicated signal transduction.

而所有步骤均可归结为癌细胞与宿主细胞及细胞外基质(Extracellular Matrix,ECM)之间的相互作用——粘附、浸润、移动、蛋白酶分泌以及复杂的信号转导过程,基于细胞信息传递和调控在细胞生命活动中处于主导地位,癌细胞信号转导系统的作用及相关机制对于揭示肿瘤转移的本质,探索新的抗肿瘤转移途径具有十分重要的作用。

The endometrium undergoescharacteristic morphological and biochemical changes under the influence of the ovarian steroid hormones in preparation for nidation. As a general regulator of implantation, the steroid hormones make effect through their receptors respectively; direct or indirect regulate the secretion of cytokines, growth factors and molecular adhesions, which may be necessary for successful implantation to occur.

比例适当的雌、孕激素通过各自的受体作用于子宫内膜,是着床的总调控师,使子宫内膜间质水肿、血管扩张充血,为胚胎着床提供物质基础;间接或直接调控着细胞因子、生长因子及粘附分子的分泌和释放。

Use instead and fasten and dig the bit to remove the hole and bottom eluvial soil after 5m (if the rock meeting high hardness while the base rock creeps into, can is it inlay rock bit get into to designing requirement hole dark by fastenning and digging and fighting the clear hole and then to use instead), in order to improve the strength of bearing the weight of of one , put the reinforcing bar cage finally , build the concrete.

本工艺基本上适应于各种土层,如软弱土层、松散杂填土、粉土、砂土、粒径不大(10cm以下)的碎石土和圆砾及其它塑性不大、粘粒较少的粘土,尤其适用于软塑、流塑、孔隙比大、高压缩性、抗剪强度小等特性的淤泥质土及因地下水丰富造成泥浆护壁困难的土层。

Firstly, pressure, enthalpy, temperature and velocity of pure water at different location of hydrothermal circulation system are described. Density and viscosity of fluid are calculated from temperature and pressure using properties of pure water. Secondly, influences of formational anisotropy and crack zone on hydrothermal circulation are analyzed.

首先讨论了热液循环系统不同部位的压力、焓、温度、水流的密度、粘度及流动速度等参数的特征,其次分析了地层非均质性、裂缝带的存在对热液循环流场的影响,最后分别模拟了近临界状态及侵入体存在情况下的热液循环。

PartⅡThe mechanism elucidation about effects ofα-(2,3)/(2,6)sialic acid on the Cx43gap-junction functions.(1) Westernblotting experiment showed that the decrease of sialic acid didn\'t changethe Cx43 expression and its phospholation level.(2) Westernblotting experiment showed sialidase didn,t change the ZO-1 expression,IP and confocal experiment showed sialidase improved the interaction of Cx43 andZO-1.(3) Westernblotting experiment showed sialidase didn\'t change N-cadherin expression,IP and confocal experiment showed sialidase promoted the complex formation ofCx43 and N-Cadherin.(4)Sialidase could increase the ERK1/2 phospholation level,and enchanedintercellular homotypic adhesion,Immunofluorometric assay showed sialidase couldpromote the N-cadherin cluster on the membrance.

第二部分:α—(2,3)/(2,6)唾液酸对肿瘤细胞CX43间隙连接功能影响的机制研究1、Westernblotting结果表明降低细胞膜表面唾液酸并不改变Cx43的表达及其磷酸化水平:但Cx43连接斑形成增多;2、Westernblotting结果表明唾液酸酶作用后细胞ZO—1表达没有改变,IP及免疫荧光共定位结果表明唾液酸酶作用后促进了Cx43与ZO-1的结合;3、Westernblotting结果表明唾液酸酶作用后细胞N-cadherin表达没有改变,IP及免疫荧光共定位结果表明唾液酸酶作用后促进了Cx43与N-Cadherin复合物的形成;4、唾液酸酶作用后细胞内ERK1/2磷酸化水平明显增加,细胞间同质粘附增加,以及免疫荧光表明唾液酸降低后可促进N-cadherin的膜成簇。

The surface of its seeds is covered by a layer of gum, Artemisia seed polysaccharide. ASP has been found to possess high viscosity which is 1800 times as much as that of gelatin and strong hydroscopicity, for which it can absorb 60 times its self weight of water, and there are aslo a great of oil in its seeds, Artemisia oil.

其种子表面富含一层胶质——ASP,ASP有很多优良的特性,如吸水性——可吸取自身重量60倍的水,高粘度——是明胶的1800倍;同时,沙蒿种子中又含有大量的油脂——沙蒿油,其又有着丰富的亚油酸。

The rheological characteristics of an artificial synovia mainly consisting of hyaluronic acid prepared by editors was discussed.

研究以透明质酸为主要成分的人工滑液的流变性质,分析添加γ-球蛋白和La-DPPC 磷脂对人工滑液流变性能和润滑性能的影响,并结合滑液粘弹性质与摩擦副表面理化性质对润滑模式进行了探讨。

This thesis studied the visbreaking technique used in Nanyang deoiled asphalt to produce heavy fuel oil.

本文通过对南阳脱油沥青为原料进行减粘裂化生产重质燃料油工艺的研究,探讨了解决南阳石蜡精细化工厂为发挥原油含蜡量高的资源优势而进行炼油深加工后重油脱油沥青的出路问题。

As Dr Cui explains in a recent issue of Nano Letters, when the ink dries, the nanotubes bind to the mesh of fibres in the fabric (it works for both cotton and polyester), making it conductive.

在最新的《纳米快报》中,崔博士解释道,当墨水干时,碳纳米管会粘附在衣服的纤维上,包括棉质或聚酯的材料,使它附有导电性。

The dynamic response of the large crosssection shallow tunnels in new sand loess under viscouselastic boundary is calculated by means of transient dynamic FEM so as to find out the weak points of the lining and the stress, deformation and safety of the tunnel structure.

对大断面浅埋砂质新黄土隧道,利用瞬态动力学有限元方法,计算了粘弹性边界条件下,隧道在Ⅷ度地震荷载作用下的动力响应,找出衬砌的薄弱部位和结构的受力、变形及安全性,为设计提供指导和参考作用。

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推荐网络例句

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。