粘膜固有层的

Seventy-five percent of UC patients exhibit perinuclear antineutrophil cytoplasmic antibodies; however, the presence of p-ANCA does not correlate with the activity or extent of colitis and is most likely an epiphenomenon.

UC相关症状的发生，最早可以识别的异常就是中心粒细胞流入粘膜固有层。75%的UC患者出现核周的抗中性粒细胞抗体；然而，p-ANCA的出现并不与结肠炎的活动或程度相关，且很可能是一个附带现象。p-ANCA的出现被用来作为诊断检查，来帮助鉴别UC和克隆恩病。

Our experiment is unique to clone porcine IL-4 gene from lymphocytes of the local species of Chenghua porcine and systematically study its expressing effect in vivo on the immune system and immune responses of mouse and pig to trivalent vaccines against Swine fever, the Pasteurellosis and Erysipelas suis and pig paratyphoid vaccine.

将得到的序列在GenBank和EMBL数据库中进行了同源比较，结果表明它与来源于长白猪肠粘膜固有层淋巴细胞的白细胞介素-4有99％同源，与来源于杂交猪T细胞的白介素-4有96％同源，说明猪种及组织细胞来源的不同可能使基因有一定的差异。

Results: All rats in experiment group devloped CAG at the end of 12 weeks with the following Pathological changes of CAG such as thin mucosa layer, thick muscle layer, decreased glandes, soakaging inflammation cells in microscope and with the time prolonging, the atrophy of gastric mucosa became more serious; In normal control group and normal feeding group, the IL-6 and IL-8 content in blood serum are the same at every time point; In experiment group, IL-6 became increased from 4wk and kept high level from 4wk to l2wk and had significant difference compared with normal controls.

结果：灌胃至12wk时出现胃粘膜层变薄，固有层腺体减少，固有层纤维结缔组织增生，粘膜肌层明显增生，慢性炎细胞浸润等萎缩性胃炎表现，随著热盐水灌胃时间的延长，32wk胃粘膜萎缩程度明显加重；正常对照组和正常餵养组大鼠各时间点血清IL-6，IL-8含量基本相同。

Results: Large number of immunoreactive fibres was detected in lamina propria and muscularis mucosae. Strong staining of ganglion cells in the Auerbach's and the Meissner's plexus were observed on the normal specimens. There was very little or no immunoreactive fibre in the lamina propria and muscularis mucosae of the aganglionic bowel. However there was strong immunoreactivity in the perineurium of the hypertrophic nerve trunks in the submucosal and intramural layers of aganglionic segments.

结果： 正常肠段的粘膜固有层和粘膜肌层中有大量的P75NGFR阳性纤维，粘膜下和肌间神经丛中神经节细胞表现为P75NGFR强阳性，痉挛段肠管粘膜固有层和粘膜肌层中P75NGFR阳性纤维明显减少或缺如，粘膜下和肌间粗大神经纤维的神经束膜表现为P75NGFR强阳性，象一个环包绕在周围。

Strong staining of ganglion cells in the Auerbach's and the Meissner's plexus were observed on the normal specimens. There was very little or no immunoreactive fibre in the lamina propria and muscularis mucosae of the aganglionic bowel. However there was strong immunoreactivity in the perineurium of the hypertrophic nerve trunks in the submucosal and intramural layers of aganglionic segments.

结果： 正常肠段的粘膜固有层和粘膜肌层中有大量的P75NGFR阳性纤维，粘膜下和肌间神经丛中神经节细胞表现为P75NGFR强阳性，痉挛段肠管粘膜固有层和粘膜肌层中P75NGFR阳性纤维明显减少或缺如，粘膜下和肌间粗大神经纤维的神经束膜表现为P75NGFR强阳性，象一个环包绕在周围。

CD8~+ cell is the main T lymphocyte subset in spleen, and B lymphocyte mainly is IgG~+ cell, moreover the amount of these B lymphocytes could exceed CD3~+ T lymphocyte subset after 7 days. CD8~+ cell is the main T lymphocyte subset in tonsil of appendix, and B lymphocyte is IgM~+ cell, and the amount could exceed CD3~+ T lymphocytes after 35 days. After 21 days, B lymphocytes in esophago tonsil are the main IgA~+ cells and the amount exceeds CD3~+ lymphocytes. The amount of CD4~+ lymphocytes is more than CD8+ lymphocytes.4. CD3~+、CD4~+ and CD8~+ T lymphocytes in spleen mainly distribute in periarterial lymphoid sheath. However IgM~+、IgG~+ and IgA~+ cells mainly distribute in ellipsoid periarterial lymphoid sheath and germinal center. T lymphocytes in appendix tonsil mainly distribute in middle and inferior part of mucous and the B lymphocytes mainly in middle and mucous between 4~7 days. Whereafter T, B lymphocytes equably distribute in mucous. CD4~+ cells arrange tightly and mainly occupy the central part in aggregates of T lymphocytes in esophago tonsil and CD8~+ lymphocytes mainly distribute in periphery. Meanwhile B lymphocytes encircle the periphery of aggregates of T lymphocytes. The aggregates of B lymphocytes is mainly the germinal center with lots of IgM~+、IgG~+ and IgA~+ cells. Meanwihle T lymphocytes encircle the periphery of aggregates of B lymphocytes.5. There is an intimate relationship between the development of tissue structure of peripheral immune organs and lymphcytopoiesis. The maturation of tissue structure is stimulated by the immigration of lymphocytes and the mature tissue structure provides place where lymphocytes grow mature and functionate.

脾脏在21日龄时达到稳定，食管扁桃体和盲肠扁桃体均在35日龄时达到稳定；脾脏中T淋巴细胞亚群以CD8~+细胞为主，B淋巴细胞则以IgG~+细胞为主，并在7日龄后数量超过CD3~+T淋巴细胞；盲肠扁桃体中T淋巴细胞亚群以CD8~+细胞为主，B淋巴细胞以IgM~+细胞为主，并在35日龄后数量超过CD3~+T淋巴细胞；21日龄后，食管扁桃体中B淋巴细胞以IgA~+细胞为主，数量超过CD3~+细胞，CD4~+细胞的数量多于CD8~+细胞。4、在T、B淋巴细胞组织定位方面，脾脏中CD3~+、CD4~+和CD8~+T淋巴细胞主要分布在动脉周围淋巴鞘中，而IgM~+、IgG~+和IgA~+细胞主要分布在椭球周围淋巴鞘和生发中心中；4～7日龄时，盲肠扁桃体中T淋巴细胞主要分布在粘膜固有层的中下部区域，而B淋巴细胞则主要分布在中上部区域，随后各日龄T、B淋巴细胞均匀地分布在粘膜固有层中；在食管扁桃体的T淋巴细胞聚集物中，CD4~+细胞紧密排列，主要占据中央部位，CD8~+细胞主要散布在外周，同时B淋巴细胞又环绕在整个T淋巴细胞聚集物的外周；B淋巴细胞聚集物主要为生发中心，其中存在大量IgM~+、IgG~+和IgA~+细胞，同时T淋巴细胞又环绕在整个B淋巴细胞聚集物的外周。5、外周免疫器官的组织结构发育和淋巴细胞发生之间存在密切的关系，淋巴细胞迁入淋巴器官刺激组织结构的发育成熟，同时成熟的组织结构又为淋巴细胞发育成熟并行使功能活动提供场所。

Effect of insufficiency of the spleen qi on precancerosis was observed on the animal models with insufficiency of the speen qi and CAG.

结果脾气虚能加重慢性萎缩性胃炎的程度，与正常对照组比较，CAG组与脾气虚型CAG组，胃体粘膜固有层厚度明显减少（P＜0.01）；胃体腺腺底相对厚度减少（P＜0.05）；胃体粘膜核分裂相频数显著增加（P＜0.01）。

Results: From the third to fourth month of the gestation, NOS positive neurons could be seen in the laming propria of tongue mucosa.

结果：第3~4个月龄时，在舌肌和舌粘膜固有层可见到胞体较小，淡染的NOS阳性神经元，分布稀疏。

P.01 . conclusion:(1) IgA of the lamina propria mucosae would lessoning while the endotoxin in portal veinwas heightening, and the lesson of the I L-6mRNA was the main reason of the lesson of IgA in the lamina propria mucosae, so, the impairment of barrier of the intestinal mucosa was caused by the impairement of the organic immunological function descent while there was obstructive jaundice existing.

(1) 肠粘膜固有层内IgA表达减少伴随门静脉血内毒素浓度的增加，而肠粘膜内IL-6mRNA表达的减少是导致肠粘膜固有层IgA表达减少的重要原因之一，因此可推论肠粘膜免疫屏障功能的受损与梗阻性黄疸时机体的免疫功能受抑有关。

Results: From the third to sixth month of gestation, some small NOS positive cells could be seen in the lamina propria mucosae. With the fetal age increased, the number of NOS positive cells increased too, and at the same time, the positive reaction of NOS increased gradually.

结果：第3~6个月龄时，胃粘膜固有层内皆可见胞体较小的NOS阳性细胞分布，随着胎龄的增加，NOS阳性细胞数目逐渐增多，染色逐步加深。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。