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Keywords dextran sulphate sodium;colitis;nuclear factor-κB;intercellular adhesion molecule-1

葡聚糖硫酸钠;结肠炎;核因子;细胞间粘附分子

METHODS Dinitrofluorobenzene was used to induce the contact dermatitis in mouse ear, rhIL-11 0.375-1.5 mgkg^(-1)d^(-1) sc for 10 d, the degree of skin inflammatory reaction was observed. At the same time, the serum level of tumor necrosis factor-α and interleukin-6(IL-6) was measured by radioimmunoassay; the serum level of nitrogen monoxidum was detected by biochemical method and the expression of intercellular adhesion molecule-1(ICAM-1) was detected by immunohistochemical method.

采用2,4-二硝基氟苯致小鼠耳部皮肤接触性皮炎试验模型,观察sc rhIL-11 0.375~1.5mgkg^(-1)d^(-1),连续10d后皮肤炎症反应程度,同时采用放射免疫分析法测定血清中肿瘤坏死因子-α和白细胞介素-6(IL-6)的水平,采用生物化学检测法测定血清一氧化氮的水平,采用免疫组化法测定皮肤中细胞间粘附分子(ICAM-1)的表达。

In the course of experimental study on re-perfusion of ischemic skeletal-muscle graft, Zamboni found that HBO could reduce leukocyte adhering to endothelia and infiltrating.

有学者在对肌瓣移植的缺血再灌注损伤进行实验研究时发现:HBO能够减少白细胞与血管内皮细胞粘附,并减少白细胞的浸润,减轻局部的炎症反应,从而减轻肌瓣的缺血再灌注损伤。

Eggplant, vitamin P, can enhance cell adhesion, lower serum cholesterol and improve microvascular flexibility.

茄子,富含维生素P,能增强细胞粘着力,降低血清胆固醇,提高微血管弹性。

Combined therapy is able to reduce the inflammatory cell adhesions and infiltrations, and alleviate inflammatory immunoreactions and neuron necrosis.

针药结合可降低炎性细胞粘附、浸润,减缓炎症免疫反应,减轻神经元坏死程度。

Objective To investigate the expression of intercellular adhesion molecules-1 (CD54) in rectal carcinoma and nearby mucous membrane and its clinical significance.

目的 探讨细胞间粘附分子-1(CD54)在直肠癌组织和邻近肠粘膜组织的表达及临床意义。

The abnomal expression of LFA-3/CD58 and CD11b of BMMNC and Ln and IL-12 of serum can affect the bone marrow haematopoiesis and are related closely to CAA.

CAA患者粘附分子LFA-3/CD58、CD11b、Ln和细胞因子IL-12表达异常,影响骨髓造血功能,可能与再障的发生密切相关。

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