粗毛

Several anti-tumor cell lines and carbonic anhydrase Ⅱ model were established. More than 10000 compounds and extracts from plants were screened using these models and about 10 compounds showed strong inhibitory activities. Two species of plants Inula helianthus-aquatica and Saussurea deltoidea were chosen to investigate chemical and bioactivity constituents based on the results of screening of extracts and fractions. 58 compounds were isolated and identified from these two plants, 6 compounds were found to be new and 14 compounds showed anti-tumor activities. We also studied the anti-tumor mechanism of the compound bigelovin isolated from Inula helianthus-aquatica. Bigelovin was found with apoptotic activity against cell line U266 by lowering the amount of important transcription factor E2F-1 which inhibits the cell cycle at G0/G1 stage. Docking study on 7 natural new phenolic inhibitors of CA Ⅱ and 3D-QSAR study on 61 sulfonamide inhibitors of CA Ⅱwere also investigated. The calculated results were in good correlation with experimental results.

基于以上两种重要疾病和研究组方向，本论文工作开展了多个肿瘤细胞株和碳酸酐酶Ⅱ靶标模型的建立和筛选工作，累计筛选1万多个/次样品，发现10余个活性较强化合物；从粗提取物筛选结果中选取两种抗肿瘤活性强的菊科植物水朝阳旋覆花(Inula helianthus-aquatica)和三角叶凤毛菊进行了系统化学和活性成分研究，分离鉴定了58个化合物，发现6个新化合物和14个抗肿瘤活性化合物；通过合作对水朝阳旋覆花中活性较强的bigelovin进行了抗肿瘤作用机制研究，发现它可能是通过降低G2期重要的转录因子E2F-1，致使细胞周期阻滞在G0/G1期，引起多发性骨髓瘤U266细胞凋亡；开展了7个新的天然酚类CAⅡ抑制剂的对接研究和61个合成的系列磺酰胺类CAⅡ抑制剂的3D-QSAR分析，结果表明计算与实验一致。

According to distribution of bryophytes on different substances, the frequencies of Bazzania albifolia, Heteroscyphus coalitus and Homaliodendron scalpellifolium in evergreen broadleaved forests of Daweishan Nature Reserve are highest; those of Macrothamnium macrocarpum, Bazzania fauriana, Ptychanthus striatus, Pogonatum cirratum and Thuidium cymbifolium are higher. Additionally, Aerobryum speciosum, Trachycladiella sparsa, Taxiphyllum subarcuatum, Aerobryidium levieri, Lepidozia wallichiana, and Leucobryum bowringii are relatively common.

根据大围山常绿阔叶林内苔藓植物在不同基质上的生长分布情况，结合其甲凡J}rg另出现的频度可知白叶鞭苔、双齿异粤苔、以及刀叶树平醉是大围山常绿阔叶林内的三大优势种；南木醉、厚角鞭苔、皱尊苔、刺边小金发鲜和大羽醉在大围山常绿阔叶林内出现的频率也很高；此外气鲜、散生粗带醉、钝叶鳞叶鲜、莱氏毛扭醉、瓦氏指叶苔、以及狭叶白发鲜等在大围山常绿阔叶林内也有一定数量的分布。

Alpaca fiber's diameter is very large. It has serial or batch wise medullate.

羊驼毛直径粗，有连续型或间断型髓腔。

Leaf blade surfaces white pubescent, apex obtuse to acute; calyx segments obscurely 3-5-veined; staminode 1-2.2 mm

叶片表面白色短柔毛，先端钝的到锐尖；花萼裂片不明显3-5脉；退化雄蕊1-2.2毫米 18 Briggsia rosthornii 川鄂粗筒苣苔

Fruit with stellate trichomes mixed with longer, simple and forked ones; fruiting pedicels erect or ascending,(1-)1.3-1.8(-2) mm, stout, subappressed to rachis

与长，单和分叉的混合的果具星状毛；果梗直立或上升，(1-)1.3-1.8(-2)毫米，粗壮，近贴伏于轴 3 A。 dasycarpum 粗果庭荠

With the scanning electron microscopy and semi-thin section at 2 μm,the surface structure and the microstructure of the skin and the skin sense receptor of Calotes versicolor were observed.

用扫描电镜和半薄切片技术对变色树蜥的皮肤及皮肤感受器的表面结构和显微结构进行了观察，皮肤感受器是位于鳞片凹窝中的帽状突起，其上有粗长的感觉毛。

The outercoat is flat, harsh, strong and shaggy, free from wooliness and curl, although a slight wave is permissible.

外层披毛平坦、粗硬、结实且蓬松，没有绒毛状或蜷曲，但是，略呈波浪状是允许的。

Plants (10-)20-150 cm tall, erect; floral tube usually with tufts of hairs on costae and at insertion of sepals at mouth of floral tube; seeds 0.8-1 mm, coarsely papillose

植株(10-)20-150厘米高，直立；在中脉上和在萼片的插入时候在花被管口的花被管通常具1束毛；种子0.8-1毫米，粗具小乳突 37

The Teddy is a relatively new breed that is being shown in the United States; it has a coarse, short and thick coat with "kinked" hair shafts without ridges or rosettes.

泰迪是一种较新的品种，，它的皮毛粗短而厚实，&卷曲&的毛不太长也没有漩涡状的结。

Knitting yarn factory owns one of eight sets of four sets of ring and mule spinning equipment, the main production and export of "Hong Kong-yu" brand all-wool, chemical fiber and other blended and woolen yarn, with an annual output up to 1000 tons.

其中针织纱分厂拥有八台套环锭纺和四台套走锭纺设备，主要生产出口&港宇&牌全毛、混纺和化纤等各类粗纺毛纱，年产量达1000吨。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。