粒细胞间的

Results The levels of IgE,IL-4and histamine in sera and the number of acidophilic cells in blood were all in-creased;The asphyxiant sign,the congestion and edema of the epiglottis,a large amount of the lightish yellow mucous fluid with some blood-filaments in the tracheae,pneumochysis,scattered petechiae on the inside surfaces and the bot-toms of both lung lobes were found;cerebromeningeal haemorrhage and cerebral edema were observed under microso-cope.

结果 检血中IgE、IL-4、组胺含量和嗜酸粒细胞数量均显著增加。死者呈窒息征象；气管喉头充血水肿，气管内有大量淡黄色夹有血丝的粘性液体，肺水肿，肺叶间及肺底部散在点状出血；脑膜出血和脑水肿。

Histological observation was performed. Results The peak of serum CINC concentrations occurred 3 h after reperfusion with the difference between the groups with and without ONO-5046 being significant. Expression peak of CINC mRNA in the pancreatic graft occurred 3 h after reperfusion with the expression level in the ONO-5046 treated group significantly lower than in the ONO-5046 untreated group. The activity of MPO in the treated group was obviously decreased as compared with in the untreated group.

结果 CINC于再灌注后3小时出现峰值，治疗组为(7.24±1.46)μg/L，对照组为(28.4±1.85)μg/L，差异显著；移植物中CINC mRNA于再灌注后3小时表达最强，治疗组的表达水平明显低于对照组；MPO的活性，治疗组显著低于对照组；治疗组的胰小叶间质水肿及胰小叶间质和胰小叶内的中性粒细胞浸润较轻。

Results Punctiform erosion, hemorrhage were observed by nake eyes in each groups. Epithelium cellular necrosis, defluxion, neutrophil being dominant in propria lamina and intact glandular were observed with microscopy. The erosion became severe with the successive stimulate of ethanol. There is no difference between distillate spirit and sodium chloride rats in Guth in 7th day, but Guth in distillate spirit rats was higher than that in sodium chloride rats in 30th day. PGE2, TGF-α contents in gastric mucosa of treated group increased significangly compared with control group. PGE2 showed no difference between each group in 7th and 30th day; TGF-α in gastric mucosa of distillate spirit and sodium chloride rats decreased after 1 month.

结果 茅台组、乙醇组、生理盐水组胃黏膜均肉眼可见程度不同的点状糜烂、出血；光镜下黏膜部分上皮坏死脱落，固有层以中性粒细胞为主炎性细胞浸润，腺体结构基本完整，病变随时间延长有所加重，Guth积分1周茅台组与生理盐水组差异无统计学意义，1月两者相比差异有统计学意义；茅台组、乙醇组胃黏膜组织内PGE2水平与生理盐水组相比明显增高，同时TGF-α表达增强；但PGE2水平各组间1周与1月相比差异无统计学意义；TGF-α表达强度在茅台组、生理盐水组1月后逐渐降低，差异有统计学意义。

Objective To observe the expression and clinical significance of receptors for granulocyte colony-stimulating factor from patients with hyperthyroidism by antithyroid-drug therapy.

目的 观察粒细胞集落刺激因子受体在甲状腺机能亢进症药物治疗患者中的表达及与粒细胞减少间的关系。

The result indicated that the percentage of lymphocyte were decreased, the percentage of neutrophile granulocytes were magnified significantly with the lighting time increasing, which was due to the level of the melatonin inhibited in the long time lighting; and to supply different exogenous dose, induce the percentage of lymphocyte were magnifying, the percentage of neutrophile granulocytes were decreased. And the statistical analysis showed there was significant difference.

结果表明：在给予不同光照时间的条件下，随着光照时间的延长，褪黑素的分泌水平受到抑制，导致具有特异免疫功能的淋巴细胞百分率下降，具有非特异免疫功能的中性粒细胞百分率上升，经统计分析表明不同组间的测定结果均存在显着差异；采用24h全天光照，用以模拟机体切除松果腺的情况，再给予一定剂量外源性褪黑素，导致机体内具有特异免疫功能的淋巴细胞百分率上升，具有非特异免疫功能的中性粒细胞百分率下降，经统计分析表明不同组间的测定结果均存在显著差异，并且高剂量褪黑素对机体的影响更为明显。

In the patient group, when comparing patients subject to active infection of any virus with those under no active infection, no difference of statistic significance between them is found in terms of age, course,frequency, admitted temperature, differential leukocyte count (neutrophilic granulocyte,achroacyte and monocytes),applying glucocorticoids or not, and EDSS point value.

病例组中任一病毒近期活动性感染者和无活动性感染者相比，其年龄、病程、发作次数、入院体温、血白细胞分类计数（中性粒细胞、淋巴细胞和单核细胞）、糖皮质激素应用与否及EDSS分值间的差异均无统计学意义。

The disease caused lesions primarily in the lungs, with histopathological changes manifesting interstitial hyperplasia, fibrin exudation, caseous necrosis, and lymphocytes, neutrophils and monocytes infiltration.

该病的病变主要集中于肺脏，其组织学变化主要是间质增生，纤维素渗出，干酪样坏死，淋巴细胞、嗜中性粒细胞和单核细胞浸润。

Mechanistically, expression of a molecule known as P-selectin by the platelets was crucial for mediating the platelet-neutrophil interaction, which induced platelets to produce proinflammatory factors such as TXA2. The authors therefore suggest that disrupting the platelet-neutrophil interaction or blocking the proinflammatory factors produced as a result of this interaction might provide new therapeutic targets for the treatment of individuals with ALI.

具体来说，体现在分子水平上就是由血小板产生的血小板蛋白对于调解血小板和中性粒细胞交互影响起着关键作用，它能够诱导血小板产生致炎因素如血栓素A2等，该文作者因此认为，或许破坏血小板与中性粒细胞间的相互作用或者阻断相互作用所产生的致炎因素可以提供一种新的方法用于治疗急性肺损伤。

DESIGN, TIME AND SETTING: In vitro cytology experiment was performed at the laboratory of Department of Pediatrics, First Affiliated Hospital of Guangzhou Medical College from December 2007 to August 2008. MATERIALS: MSCs were provided by 30 leukemia children admitted to First Affiliated Hospital of Guangzhou Medical College, including 22 acute lymphoblastic leukemia and 8 acute myeloblastic leukemia.

材料：骨髓间充质干细胞来源于广州医学院第一附属医院住院的30例白血病患儿，其中急性淋巴细胞白血病患儿22例，急性粒细胞白血病8例，患儿家属对实验均签署知情同意书。K562/AO2细胞株由天津血液病研究所提供。

METHODS: The presence and number of recently developed extra-articular manifestations and a weighted EAM score, as well as the levels of serological markers, were compared between 31 patients with RA with histologically proven vasculitis and 50 patients with RA in whom vasculitis could not be documented histologically. The following markers were evaluated: circulating immune complexes, complement components C3 and C4, class-specific rheumatoid factors, antineutrophil cytoplasmic antibodies, antinuclear antibodies, antiendothelial antibodies, circulating intercellular adhesion molecule-1 and -3, circulating vascular cell adhesion molecule and E-selectin, cellular fibronectin, von Willebrand factor antigen, and C reactive protein.

对比组织学上已证实有血管炎的31例 RA 例和组织学上无血管炎的50例 RA 患者间的临床及血清学标记物，这些资料包括最近发生的关节外表现数量、关节外表现加权得分、循环免疫复合物、补体 C3和 C4、类风湿因子（ IgM-RF，IgG-RF，IgA-RF ）、抗中性粒细胞胞浆抗体、抗内皮细胞抗体、循环细胞间粘附分子-1和-3、循环血管内皮粘附分子和 E-选择素、细胞纤连蛋白、假性血友病因子抗原（ von Willebrand factor antigen ）及 C-反应蛋白。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。