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The results suggest that when the analyzer warns anything about monocytes and basophils, it is better to analyze them under microscopy.

在仪器有白细胞相关各类提示警告时,无论单核细胞、嗜碱性粒细胞是否在正常范围,应镜检为宜。

First, Fc R1 densities on basophils from allergic and nonallergic persons range from 104 to 106 per cell, and several hundred thousand IgE receptors are usually occupied with IgE.

首先,过敏和非过敏性人群的嗜碱性粒细胞表面的FcR1密度范围为104-106/细胞,通常成百上千的IgE受体已与IgE结合。

They found that treatment with rhuMAb-E25 decreased free IgE levels to 1% of pretreatment levels and resulted in marked down-regulation of FcR1 on basophils.

结果发现rhuMAb-E25治疗可使游离IgE水平降至治疗前的1%,并致嗜碱性粒细胞表面FcR1表达显著下调。

SUMMARY: Mast cells are the key elements in chronic urticaria pathogenesis, whereas basophils should be regarded as bystanders and serve as biomarkers in some chronic urticaria subsets.

小结:肥大细胞是慢性荨麻疹发病过程中的关键因素,而嗜碱性粒细胞应被视为旁观者,在某种亚型的慢性荨麻疹中作为生物标记物。

Second, only about 2000 IgE molecules are required for a half maximal release of histamine from basophils exposed to specific allergen.

其次,当嗜碱性粒细胞受特异性抗原刺激时,只需约2000个IgE分子便可释放其所含组胺量的一半。

Certain patients with ClU exhibited elevated histami ne-releasing activity in their serum. This implies unusual activating mechanism of their mast cells and basophils. It may be related to autoimmunity.

部分慢性特发性荨麻疹患者血中组胺释放活性增高,提示该类病人具有特殊的肥大细胞和嗜碱性粒细胞激活机制,很可能与自身免疫有关。

These reviews provide an up-to-date and informative discussion on signaling, proteases, and glycans as promoting molecules, the nature of white cells (natural killer, mast cells, and basophils) and importantly on Regulatory T cells.

在了解信号传导、蛋白酶和作为促进分子的葡聚糖,以及天然白细胞(自然杀伤细胞、肥大细胞和嗜碱性粒细胞),调节T细胞的重要性等方面,这些综述为大家提供了最新的、内容丰富的知识。

Methods: The number of microglia treated with different doses of carbachol and GM-CSF was determined by MTT assay.

培养的小胶质细胞系,加入不同浓度的卡巴胆碱或卡巴胆碱与粒细胞巨噬细胞集落刺激因子(Granulocyte-Macrophage Colony-Stimulating Factor, GM-CSF),用MTT方法检测细胞活性,观察对小胶质细胞数量的影响。

Results: We found that carbachol decreased the number of microglia even in the presence of GM-CSF in dose-dependent manner, with the most effective concentration of 10μM.

结果:我们在培养的小胶质细胞系发现,卡巴胆碱显著减少小胶质细胞的数量,并能有效抑制粒细胞巨噬细胞集落刺激因子诱导的小胶质细胞数量增多,并存在剂量依赖效应,10μ M浓度效果最为显著。

AIM: To investigate the effect of different culture systems on IL6 release in model of coculture of human bronchial epithelial cells and eosinophils.

目的:以支气管上皮细胞和嗜酸粒细胞共培养为实验模型,探讨不同培养方式对IL6释放的影响。

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