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粒细胞

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The main side effects include thrombopenia, neutropenia, gastrointestinal tract response, and hypothyroidism.

最主要的副反应包括:血小板减少症、中性粒细胞减少症、胃肠道反应及甲状腺功能减低症。

Meta-analyses showed that the response rate of TP (topotecan + cisplatin) regimen had no significant difference compared with EP regimen (etoposide + cisplatin) with OR 0.83 and 95%CI 0.63 to 1.09, but myelo-suppression such as leucopenia and thrombopenia was more severe with TP regimen; the response rate of monotherapy with topotecan was similar with that of CE (carboplatin + etoposide) regimen with OR 0.59 and 95%CI 0.22 to 1.60; the response rate of TEP (topotecan + etoposide + cisplatin) regimen was comparable with that of EP regimen with OR 1.37 and 95%CI 0.82 to –2.28, but myelosuppression and anemia were more severe with TEP regimen; the response rate with OR 0.97 and 95%CI 0.60 to –1.57, median time to progression with WMD –2.32 and 95%CI –5.72 to 1.09 and median survival time with WMD –1.65 and 95%CI –7.13 to 3.83 of IV topotecan were similar to those of oral topotecan, while neutropenia was more severe with IV topotecan.

Meta分析结果表明,TP 方案与EP方案的反应率相似 [OR 0.83, 95%CI (0.63,1.09)],但具有相对高的致血小板下降的骨髓毒性;单药拓朴替康与CE方案的反应率相似 [OR 0.59, 95%CI (0.22,1.60)];TEP方案(拓扑替康+足叶乙甙+顺铂)与EP方案的反应率相似 [OR 1.37, 95%CI (0.82,2.28)],TEP方案致化疗后重度白细胞下降、重度血小板下降、重度血红蛋白下降均高于EP方案;口服拓扑替康与静脉滴注拓扑替康的化疗后反应率 [OR 0.97, 95%CI (0.60,1.57)]、中位疾病进展期 [WMD –2.32, 95%CI (–5.72, 1.09)]、中位生存期 [WMD –1.65, 95%CI (–7.13,3.83)] 相似,口服拓扑替康化疗后重度中性粒细胞下降明显低于静脉滴注拓扑替康。

Meta-analysis based on included studies showed that response rate of TP regimen has no statistic significance compared with EP regimen[OR0.83,95%CI(0.63-1.090)],but myelo-suppression such as leucopenia and thrombopenia is more severe; response rate of single topotecan has no statistic significance compared with CE regimen[OR0.59,95%CI(0.22-1.60)]; response rate of TEP regimen has no statistic significance compared with EP regimen [OR1.37, 95%CI(0.82-2.28)], but myelo-suppression such as leucopenia, thrombopenia and anemia is more severe; response rate of IV topotecan has no statistic significance compared with Oral topotecan[OR0.97, 95%CI(0.60-1.57)],so as median time to progression[WMD-2.32, 95%CI(-5.72,1.09)] and median survival time[WMD-1.65, 95%CI(-7.13,3.83)],while neutropenia is more sever in IV topotecan than Oral topotecan.

分析表明,TP方案与EP方案的反应率相似[OR0.83,95%CI(0.63-1.090)],但具有相对高的致白细胞和血小板下降的骨髓毒性;单药拓扑替康与CE方案的反应率相似[OR0.59,95%CI(0.22-1.60)];TEP方案与EP方案的反应率相似[OR1.37,95%CI(0.82-2.28)],TEP方案致化疗后重度白细胞下降、重度血小板下降、重度血红蛋白下降均高于EP方案;口服拓扑替康与静脉滴注拓扑替康的化疗后反应率[OR0.97,95%CI(0.60-1.57)]、中位疾病进展期[WMD-2.32,95%CI(-5.72,1.09)]、中位生存期[WMD-1.65,95%CI(-7.13,3.83)]相似,口服拓扑替康化疗后重度中性粒细胞下降明显低于静脉滴注拓扑替康。

5Ug/ml without toxical effect on both cells activity was selected as the high dose to observed the effect on HUVEC and human peripheral polymorphonuclear cell activity by MTT and trypan-blue assay repectively.

2.2 疡愈涂剂对白细胞与血管内皮细胞粘附影响的分子机制用MTT法检测YYTJ对HUVEC活力的影响,用台盼蓝计数法检测YYTJ对人外周血中性粒细胞活力的影响。

Objective:To investigate therapeutic efficiency,toxity and side effect in treating acute promyelocytic leukemia with Compound Huangdai Tablets.

目的:探讨复方黄黛片治疗急性早幼粒细胞白血病的疗效及毒副作用。

Objective: To explore the eosinophil infiltration on the transitionary process of nasal mucosa following nasal endoscopic surgery.

目的:探讨嗜酸性粒细胞(eosinophils, EOS)浸润对鼻息肉术后鼻腔黏膜转归及疗效影响的因素。

ABSTRACT] Objective: To explore the eosinophil infiltration on the transitionary process of nasal mucosa following nasal endoscopic surgery.

探讨嗜酸性粒细胞(eosinophils, EOS)浸润对鼻息肉术后鼻腔黏膜转归及疗效影响的因素。

ABSTRACT] Objective: To explore the eosinophil infiltration on the transitionary process of nasal mucosa following nasal endoscopic surgery.

探讨嗜酸性粒细胞(eosinophils, EOS)浸润对鼻息肉术后鼻腔黏膜转归及疗效的因素。

In contrast to lung sequestration of neutrophil count,there were no transpulmonary gradient of MBE between left and right atrium after aortic declamping.

与主动脉开放后中性粒细胞在肺内滞留相比,左房与右房血中的MBE没有差异。

Objective To investigate the cytotoxic activity of neutrophils on the muscular stage larvae of Trichinella spiralis.

目的 探讨感染旋毛虫大鼠中性粒细胞在免疫血清协助下对旋毛虫肌幼虫的杀伤作用。

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