粒细胞

AbstractObjectiveTo observe the therapeutic efficacy of all-trans retinoic acid combined with arsenic trioxide(As2O3) on acute promyelocytic leukemia.

中文摘要：摘要目的研究全反式维A酸联合三氧化二砷治疗急性早幼粒细胞性白血病可产生的协同作用。

Acute promyelocytic leukemia ; All-transrefinoic acid ; Arsenic

急性早幼粒细胞白血病；全反式维甲酸；砷剂

An D-dimeride analysis of the therapeutic effects and reactions in treating acute promyelocytic leukemia with intravenous arsenic trioxide or all-trans retinoic acid.

三氧化二砷不同给药方法治疗急性粒细胞白血病的临床观察和随访。

ABSTRACT］ Objective To observe the efficacy and side effects of combined therapy with alltrans retinoic acid, arsenic trioxide (As2O3) and chemotherapeutics for newly diagnosed acute promyelocytic leukemia.

急性早幼粒细胞白血病是急性髓系白血病中的一种独特类型(M3型)，以特异的染色体易位t(15，17)(q22，q21)为特征，形成PMLRARa融合基因，该融合基因是APL发病的分子基础和分子标志。

Objective To investigate the risk factors, clinical features and outcome of invasive aspergillosis in nonneutropenic patients.

目的 了解非中性粒细胞缺乏患者发生侵袭性曲霉病的危险因素、临床特征及预后。

Results The levels of IgE,IL-4and histamine in sera and the number of acidophilic cells in blood were all in-creased;The asphyxiant sign,the congestion and edema of the epiglottis,a large amount of the lightish yellow mucous fluid with some blood-filaments in the tracheae,pneumochysis,scattered petechiae on the inside surfaces and the bot-toms of both lung lobes were found;cerebromeningeal haemorrhage and cerebral edema were observed under microso-cope.

结果 检血中IgE、IL-4、组胺含量和嗜酸粒细胞数量均显著增加。死者呈窒息征象；气管喉头充血水肿，气管内有大量淡黄色夹有血丝的粘性液体，肺水肿，肺叶间及肺底部散在点状出血；脑膜出血和脑水肿。

In BAL fluid, there was a significant increase in neutrophils but a significant decrease in macrophages.

严重哮喘患者痰液和BAL中的嗜酸性粒细胞增加三倍，但差异无统计学意义。

Methods The immobilizing conditions of neutrophil alkaline phosphatase staining were detected by the stationary liquid of 40%, 60% and 80% acetone-citric acid, and at the same time, the staining conditions were detected at 10, 15 and 20 minutes in the matrix liquid prepared respectively with 2-amino-2-methyl-1.3-propylene glycol (PH9.4-9.6) buffer, barbital (PH9.2) buffer and Tris (PH9.2) buffer.

用40%、60%、80%的丙酮-枸缘酸固定液对中性粒细胞碱性磷酸酶染色固定条件进行测定。同时用2-氨基-2-甲基-1.3-丙二醇(pH9.4-9.6)缓冲液、巴比妥(pH9.2)缓冲液、Tris(pH9.2)缓冲液配制的基质液分别在10、15、20分钟的染色条件进行测定。

Objective To investigate the effect of oleanolic acid on the expression of bcl-2 and bax gene in HL60 cells.

目的 探讨齐墩果酸对人急性早幼粒细胞白血病HL60细胞bcl-2和bax基因表达的影响。

Now, CD11a monoclonal antibody, LFA-3/IgG1 fusion protein and TNF-αhave been successfully applied in the immunotherapy of psoriasis, and animal experiments have primarily confirmed the therapeutic effects of anti-granulocyte-macrophage colony stimulating factor IgG1,anti-CD4 monoclonal antibody and anti-complement receptor 3 antibody, which are hopeful to be the breakthrough of psoriasis treatment in the future.

一些新的免疫学研究发现，CD11a单抗、LFA-3/IgG1融合蛋白、TNF-α已经成为银屑病免疫治疗中较为成熟的疗法，而粒细胞-巨噬细胞集落刺激因子单抗IgG1，CD4单抗及补体受体3抗体的治疗作用在动物实验中已得到初步验证，有望为银屑病的治疗提供新的突破点。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。