粒细胞

Results:(1) Progesterone-treated models showed intact nasal mucosa, regular ciliary lining and inactive glands;(2) Untreated or normal saline treated models showed disrupted mucosa, inverted cilia and massive mucosal infiltration of neutrophils;(3) Smearing of nasal discharge revealed limited vs abundant number of neutrophils in SD models treated with progesterone vs untreated or treated with normal saline.(4) Hoechst stain: significantly fewer apoptotic cells per field were found in progesterone-treated models (1.583 ± 0.28) compared with untreated or normal saline treated models (2.85 ± 0.285 and 4.8 ± 0.715, respectively).

结果：(1)用黄体酮滴鼻液治疗的SD大鼠鼻腔黏膜上皮完整，纤毛整齐，腺体开放不多；(2)用或不用生理盐水滴鼻液治疗的SD大鼠鼻腔黏膜上皮纤毛倒伏，上皮结构散乱，上皮层大量中性粒细胞浸润；(3)鼻腔分泌物涂片示黄体酮滴鼻液治疗的SD大鼠有少许中性粒细胞，而用或不用生理盐水滴鼻液治疗的SD大鼠鼻腔分泌物含有大量中性粒细胞；(4)Hoechst染色：用黄体酮滴鼻液治疗的SD大鼠鼻腔黏膜上皮凋亡细胞数［(1.583±0.28)/视野］明显少于用或不用生理盐水滴鼻液治疗的SD大鼠［分别是(2.85±0.285)/视野和(4.8±0.715)/视野］。

RESULTS Multivariate analysis showed that the age, degree and duration of agranulocytosis,chemotherapy period and granulocyte colony stimulating factor were significantly independent risk factors.

结果 年龄、粒细胞缺乏程度、低粒细胞持续时间、化疗周期和预防使用粒细胞集落刺激因子对医院感染的发生有显著意义(P 。0 5 )。

The test results of 20 blood samples detected on different hematological analyzers were analyzed by a q test which indicated that there were no statistical differences between blocks（P＞0.05）. The correlative coefficient was over 0.97 and the relative deviation was within the range of allowable error.

白细胞分类中，中性粒细胞和淋巴细胞在各比对仪器之间以及仪器与手工分类之间的相关性较好，而嗜酸粒细胞、嗜碱粒细胞和单核细胞，不论在各仪器还是仪器与手工分类之间，都存在较大的试验误差（P＜0.05，P＜0.01）。

Results: 1 The capacity of engulfment of A549 cells started enhancing at the 1h of preincubation with dexamethasone, reached the highest at the 4h of preincubation,At the 8h、24h of preincubation the capacity of engulfment evidently reduced. 2 Glucocorticoid cytosolic receptors antagonist RU38486 inhibited the improved engulfment ability by dexamethasone. 3Phagocytosing apoptotic eosinophils did not change the release of IL-6 and IL-8,but can inhibited the release of IL-6 and IL-8 from A549 cells stimulated by lipopolysaccharide. 4Increasely uptaking by dexamethasone also did not agitate the release of IL-6 and IL-8 from A549 cells. Conclusion: 1Dexamethasome improve the phagocyte capacity for apoptotic eosinophils of A549 cells by glucocorticoid cytosolic receptors, and the effect presents time-dependently. 2Phagocytosis of apoptotic eosinphils can degrade inflammatory reflection, so it is likely to be critical in the control of asthma inflammation.

结果： 1 A549细胞在地塞米松诱导后1小时吞噬能力开始升高，4小时吞噬能力达最高峰，8小时、24小时吞噬能力明显下降 2加入RU38486后抑制了地塞米松所增强的吞噬能力 3凋亡嗜酸粒细胞的吞噬并不能改变A549细胞释放IL-6和IL-8，但能抑制脂多糖刺激A549细胞后IL-6、IL-8的分泌 4地塞米松增加的吞噬也不激发A549细胞释放IL-6和IL-8 结论： 1地塞米松促进A549细胞吞噬凋亡的嗜酸粒细胞是通过A549细胞糖皮质激素胞浆受体发挥作用的，并且具有时间依赖性 2 A549细胞吞噬凋亡的嗜酸粒细胞能降低炎症反应，对哮喘炎症的控制具有重要意义

Cases of eosinophilia were collected and chromosome specimens of bone marrow cells were prepared by 24hour culture, and Gbanding technique was used for karyotyping.

为探讨染色体异常克隆在嗜酸性粒细胞增多症诊断和鉴别诊断中的意义及克隆性嗜酸性粒细胞增多症涉及的染色体异常，收集了65例嗜酸性粒细胞增多患者的骨髓标本，培养24小时，采用G显带进行核型分析。

Results There were significant differences between MDS and CAA in Hb, red cell distribution width-coefficient variation, immature reticulocyte fraction, BPC, the ratio of G1 (the sum percentage of myeloblast and premyelocyte) to G2 (the sum percentage of neutrophilic myelocyte and metamy-elocyte), the ratio of E1 (the sum percentage of proerythroblast and early erythroblast) to E2 (the sum percentage of intermediate erythroblast and late erythroblast), megakaryocyte count,erythroblast PAS, neutrophil alkaline phosphatase, and serous levels of indirect bilirubin,lactose dehydrogenase, folic acid, VitBl2 and ferritin.

结果 MDS患者血红蛋白，红细胞体积分布宽度。变异系数、未成熟网织细胞比率、血小板计数、骨髓原始细胞及早幼粒细胞之和与中性中幼粒细胞及中性晚幼粒细胞之和的比值、原始红细胞及早幼红细胞之和与中幼红细胞及晚幼红细胞之和的比值、巨核细胞计数、有核红细胞糖原染色阳性率和阳性指数、中性粒细胞碱性磷酸酶染色阳性率和阳性指数、血清间接胆红素、乳酸脱氢酶、尿酸、叶酸、维生素B12(VitB12)、铁蛋白水平等常规实验室指标与CAA患者比较差异有统计学意义。

No primitive blood cells were observed in liver, which implies that the liver was not the hemopoietic organ in C. mydas. The development of erythrocytes includes 5 stages: primitive, early, middle, late, and mature. The body sizes of these cells increased first, then decreased, and increased in the end. The development of granulocytes includes 5 stages also: myeloblast, promyelocyte, meddle immature granulocytes, late immature granulocytes, and mature granulocytes. The body sizes of them decreased; and the sublobe of the nuclear may indicate the aging.

红血细胞的发育经历了5个阶段：原红血细胞、早幼红血细胞、中幼红细胞、晚幼红血细胞和红血细胞等阶段，其胞体体积经历了由小到大，由大到小、再到大的发育过程；粒细胞的发育经历了5个阶段：原粒细胞、早幼粒细胞、中幼白细胞、晚幼白血细胞和白细胞等阶段，胞体体积均由大到小变化，核分叶可能是粒细胞的衰老的标志；淋巴细胞和单核细胞的发育各经历了3个阶段。

The results indicated that in the FNAC smears of mediastinal tumor, neutropilic myelocyte, neutropilic metamyelocyte, neutropilic stab granulocyte and neutropilic segmented granulocyte were observed in granulocytic series; early normoblast, polychromatic normoblast and orthochromatic normoblast were observed in erythrocytic series; and granular megakaryocyte, thromocytogenic megakaryocyte, scattered platelet and matured lymphocyte also were observed. Cell morphology and distribution in different stages were are similar to that in bone marrow smear, and these cells belong to the extra-medullary hemopoietic tissue.

结果表明：纵隔肿块的细针抽吸活组织的细胞学涂片显示粒系细胞中可见中性中幼粒细胞、中性晚幼粒细胞、中性杆状粒细胞、中性分叶核粒细胞；红系细胞中可见早幼红细胞、中幼红细胞、晚幼红细胞；并可见颗粒巨核细胞、产血小板的巨核细胞、散在血小板及成熟淋巴细胞；细胞形态及各期细胞分布与骨髓片相似，为髓外造血组织。

Induction of Lactoferrin and IL-8 Release from Human Neutrophils and IL-5, IL-6 and RANTES Secretion from Human Eosinophils by Tryptic Enzymes via Proteinase Activated Receptor 2

PAR2介导的中性粒细胞乳铁蛋白和IL-8的释放以及嗜酸性粒细胞IL-5，IL-6和RANTES的释放论文标题：PAR2介导的中性粒细胞乳铁蛋白和IL-8的释放以及嗜酸性粒细胞IL-5，IL-6和RANTES的释放

BE1 monoclonal antibody can be used to detect basophils in tissue.

BB1单克隆抗体可有效地用于支气管肺组织标本的嗜碱性粒细胞免疫组织化学检测，同时急性发作的致死性哮喘患者气道中嗜碱性粒细胞明显增加，可能与哮喘病情恶化、甚至死亡有关，而非致死性的慢性哮喘患者气道中嗜碱性粒细胞与对照组无异，说明嗜碱性粒细胞可能主要参与哮喘的急性病程。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。