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This thesis is concerned with the synthesis of new chiral sulfinyl NADH models, whose key step is the synthsis of chiral R-3-pyridyl sulfoxides.

本论文的研究工作主要是合成新的手性亚砜类辅酶NADH模型物,工作重点在手性R基-3-吡啶基亚砜的合成上。

The lack of any diastereoselectivity for the formation ofβ-hydroxyketones with optically active sulfinyl analogue of NAD~+ model supports the radical mechanism proposed previously.

并将手性的亚砜类辅酶NAD~+模型物用于反应,没有得到立体选择性产物,验证了先前提出的自由基机理。

An efficient method for the selective hydrogenation of a series ofα,β-epoxyketones toβ-hydroxyketones using catalytic amount of two sulfinyl analogues of NAD~+ model compounds is reported.

利用两个亚砜类辅酶NAD~+模型物的催化反应,实现了α,β-环氧酮向β-羟基酮的高效转化。

Part III: Catalytic hydrogenation ofα,β-epoxyketones toβ-hydroxyketones with two sulfinyl analogues of coenzyme NADH models.

第三部分:亚砜类辅酶NAD~+模型物催化氢化α,β-环氧酮生成β-羟基酮的反应。

Results In the 421 succus prostaticus samples,278 strains pathogenic microorganisms of 15 genera were isolated from the 273 succus prostaticus samples,and the major pathogenic microorganisms was Staphylococcus aureus(57.2%) and Coagulase negative staphylocous(17.3%.The drug resistance rate of staphylococcus to penicillinG,erythromycin and albomycin was 88%-97%,and it was 33%-50% to fluoroquinolones.The drug resistance rate of staphylococcus to amikacin,cefazolin,nemycin,rifampicin and cefoperazone was lower than 30%,and they all appeared susceptible to vancomycin.

结果 421例前列腺液标本,273例分离出细菌,共分离出15个种别共计278株病原菌,其中金黄色葡萄球菌占57.2%,凝固酶阴性葡萄球菌占17.3%;葡萄球菌对青霉素G、红霉素、白霉素耐药率为88%~97%,对氟喹诺酮类耐药率为33%~50%,对丁胺卡那霉素、头孢唑啉、新霉素、利福平和头孢哌酮耐药率均0%,对万古霉素全部显示敏感。

objective to study the infection and sensitivity to antimicrobial agents of staphylococcus of bacterial prostatitis patients.methods the results of bacteriology and drug susceptibility of 421 patients,who were suffered from prostatitis,were analysed retrospectively.results in the 421 succus prostaticus samples,278 strains pathogenic microorganisms of 15 genera were isolated from the 273 succus prostaticus samples,and the major pathogenic microorganisms was staphylococcus aureus(57.2%) and coagulase negative staphylocous(17.3%.the drug resistance rate of staphylococcus to penicilling,erythromycin and albomycin was 88%-97%,and it was 33%-50% to fluoroquinolones.the drug resistance rate of staphylococcus to amikacin,cefazolin,nemycin,rifampicin and cefoperazone was lower than 30%,and they all appeared susceptible to vancomycin.conclusion staphylococcus is the main germ of bacterial prostatitis and it appears high drug resistance to usual antibacterials.staphylococcus is susceptible to vancomycin,amikacin,cefazolin,neomycin,rifampicin and cefoperazone.

目的 探讨细菌性前列腺炎患者葡萄球菌的感染状况及抗菌药物敏感性。方法回顾分析421例前列腺炎患者标本的细菌学和药物敏感性试验结果。结果 421例前列腺液标本,273例分离出细菌,共分离出15个种别共计278株病原菌,其中金黄色葡萄球菌占57.2%,凝固酶阴性葡萄球菌占17.3%;葡萄球菌对青霉素g、红霉素、白霉素耐药率为88%~97%,对氟喹诺酮类耐药率为33%~50%,对丁胺卡那霉素、头孢唑啉、新霉素、利福平和头孢哌酮耐药率均0%,对万古霉素全部显示敏感。结论葡萄球菌是细菌性前列腺炎的最常见病原菌,对临床常用抗菌药物具有较高的耐药性,葡萄球菌对万古霉素、丁胺卡那霉素、头孢唑啉、新霉素、利福平和头孢哌酮较为敏感。

By using local intoxication of soman (pinacolyl methylphospho-nofluoridate) the processes of regeneration of AChE activity at motor end-plates and of recovery of neuro-muscular transmission of rat diaphragm were observed. An ameliorative effect of HI-6 on these processes was also observed.

用大鼠的在体膈肌局部索曼中毒法,观察了乙酞胆碱酯酶在运动终板的再生和肌接头传递功能的恢复过程,以及肪类药物(HI-6)对两过程的促进作用。

Cocoa butter equivalentproduction from palm oil m idfractionand stearic acid methyl esterby interesterification cataly zed by 1,3 specific lipases in solvent free system was studied.

研究了在无溶剂系统中,利用 1,3位置特异性脂肪酶催化POMF与硬脂酸甲酯进行酯交换反应制取类可可脂。

Aiming at the unbalance of the diabetes patients which owing to metabolism turbulence of blood glucose, protein, fattiness, water and electrolyte, and adopting scientific herbal prescription through enzymolysis, extraction and concentration separates the crystal of "active blood-regulating plant insulin ". It can fully restore and reinforce the function of insulin, decompose or melt the fattiness materials. For the people whose blood glucose is very high or can't reduce stiffly, it can quickly eliminate the excessively eat, drink and urine complications etc. For the patients with slight symptom, low-dosage treatment can stabilize the blood glucose and avoid the complications.

针对糖尿病人血糖、蛋白质、脂肪、水及电解质代谢紊乱导致的人体平衡失调,科学组方中草药,经过酶解、萃取、浓缩,分离出被中西方医学界称为&植物活胰调血素&的晶体,具有全面修复和增强胰岛功能,分解消溶脂类物质,针对血糖过高或顽固不降的人群使用,能够快速消除多食、多饮、多尿、四肢无力、心慌胸闷,小便发白,视力下降等糖尿病并发症。

Neomycin is one of the aminoglycoside antibiotics,and on the cellular level it inhibits phospholipase C.

新霉素是一种氨基甙类抗生素,在细胞水平可以抑制磷脂酶C介导的信号转导系统。

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My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

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