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Coli. The bacterially expressed SPE-16 also demonstrated ribonuclease-like activity in vitro.

活性实验显示,天然和重组的SPE16蛋白都具有明显的类核糖核酸酶活性。

Bis-(2,3-dibromo-4,5-dihydroxy-phenyl)-methane is a natural bromophenol with significant inhibition against PTP1B IC_(50=2.4μmol/L, which was isolated from the ethanol extract of red algae Rhodomela confervoides.

双-(2,3-二溴-4,5-二羟基苯基)-甲烷是从松节藻醇提物中分离鉴定出的溴酚类化合物,体外活性筛选发现,它具有极强的蛋白酪氨酸磷酸酶1B(PTP1B)抑制活性IC_(50=2.4μmol/L。

Aim To design and synthesize a series of novel γ-butyrolactone derivatives with FAS inhibition activities, C75 as the lead compound.

摘要目的以C75为先导化合物,设计、合成γ-丁内酯类衍生物,并研究其脂肪酸合成酶(fatty acid synthase, FAS)的抑制活性,以期发现新颖的FAS抑制剂。

Several non-enzymatic types of browning reactions that might possibly occur in citrus juice during storage were also discussed, the result indicated that degradation of Vc was the main cause of browning, whereas the possibility for Maillard reaction, Caramelization, Polyphenol oxidation and condensation to take place in juice was little.

在贮藏过程中,还对橙汁中可能发生的几种非酶褐变类型进行了探讨,发现Vc的降解反应是橙汁褐变的主要原因,而美拉德反应、焦糖化反应或酚类化合物的氧化缩合反应在橙汁中发生的可能性都很小。

Comparison of thermodynamic parameters show dioxocyclam-base Zn complex in CTAB micellar solution is a good model of carboxy anhydase CA.

热力学参数的对比表明表面活性剂CTAB胶束溶液中二氧环胺类Zn配合物是一个很好的碳酸酐酶CA的模拟模型。

The real-time quantitative PCR results showed that the expression level of two genes did not be affected by HHO obviously, whereas, the expression level of CHS gene had down regulation of different degree, except in 1.0 mM of HHO's concentration. It meaned that CHS gene is probably related with the metabolism of allelochemical.4. The Chalcone synthase gene (EaCHS1) of E.

荧光定量PCR的结果表明,萜类代谢途径中的两个关键酶基因的表达水平,没有因为羟基泽兰酮的诱导而表现出显著的差异;CHS基因的表达水平,除了在羟基泽兰酮处理浓度为1.0 mM时的差异不显著之外,在其他处理浓度均有不同程度的下调,说明该基因与化感物质的代谢途径相关。4。

Because many antineoplastic drugs are also metabolized by the CYP system, coadministration with cART could result in either drug accumulation with increased toxicity, or decreased efficacy of one or both classes of drugs.

因为有许多抗肿瘤药物也是通过细胞色素酶系统来代谢的,当它们和抗逆转录病毒药物联合使用时会导致药物累积毒性增强,或者是某一类或几类药物疗效的下降。

A novel class of autoantigens of anti-neutrophil cytoplasmic antibodies in necrotizing and crescentic glomerulonephritis: the lysosomal membrane glycoprotein h-lamp-2 in neutrophil granulocytes and a related membrane protein in glomerular endothelial cells.

PMID 7836914一种新型的类自身的抗中性粒细胞胞浆抗体和细胞坏死性新月体肾炎:在溶酶体膜糖蛋白氢灯- 2的中性粒细胞和相关的膜蛋白在肾小球内皮细胞。

In order to further understand combining characteristic of cyclohexyl methylphosphonofluoridate and isopropyl methylphosphonofluoridate and contribute more scientific data for its medical protection, the potency of inhibition of acetylcholinesterase activity induced by GF, GF+GB and the effects of reactivation by oximes pyramidoxime monohydrate(HI-6) and pyridine-2-aldoxime methylchloride(2-PAM-Cl) in rat brain were investigated with DTNB microanalysis in this study.

为进一步了解甲氟膦酸环己酯与甲氟膦酸异丙酯的联合特性,为制订医学防护措施提供更多的理论依据,用微量DTNB法对GF,GB和GF与GB混合对大鼠脑乙酰胆碱酯酶的抑制及肟类重活化剂酰胺磷定(HI-6)和氯磷定(2-PAM-Cl)的重活化作用进行了研究。

objective to analyze the drug resistance of staphylococcus aureusand provide suggestion for clinical rational use of antibiotics.methods secretion of those neonates suffered primary skin soft tissue infection and admitted during june,2005 to december,2007 was cultured and 113 strains of staphylococcus aureus were detected.we used k-b diffusion methods to determine their susceptibility to the common used antibiotics.results resistance rates of staphylococcus aureus to ampicillin/sulbactam,penicillin-g and cefazolin were 14.2%,40.7%and 6.2% respectively; there was no vancomycin-resistant strain.conclusion the resistance of staphylococcus aureus is not a serious problem in neonatal dermatic soft tissue infection.local treatment is the major approach in clinic,while general anti-infection consisting mainly of penicillin and first generation cephalosporin is chosen to avoid resistance mutation of staphylococcus aureus resulted from abuse of antibiotics.

多重聚合酶链反应快速鉴别葡萄球菌及。。。乳腺脓肿分离到葡萄球菌的鉴定和药敏。。。目的探讨金黄色葡萄球菌的耐药性,指导临床合理用药。方法对我院2005年6月至2007年12月新生儿原发性皮肤软组织感染患儿的分泌物进行培养,共检出金黄色葡萄球菌113株,并采用kb纸片扩散法对其进行常用抗生素的药敏试验。结果金黄色葡萄球菌对氨苄西林/舒巴坦、青霉素g及头孢唑啉的耐药率分别为14.2%、40.7%和6.2%,未发现耐万古霉素金黄色葡萄球菌。结论在新生儿皮肤软组织感染中金黄色葡萄球菌的耐药问题并不十分严重,临床处理应以局部为主,全身抗感染治疗宜以青霉素及i代头孢类抗生素为主,避免过度使用抗生素加速金葡菌的耐药突变。

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Finally, according to market conditions and market products this article paper analyzes the trends in the development of camera technology, and designs a color night vision camera.

最后根据市场情况和市面上产品的情况分析了摄像机技术的发展趋势,并设计了一款彩色夜视摄像机。

Only person height weeds and the fierce looks stone idles were there.

只有半人深的荒草和龇牙咧嘴的神像。

This dramatic range, steeper than the Himalayas, is the upturned rim of the eastern edge of Tibet, a plateau that has risen to 5 km in response to the slow but un stoppable collision of India with Asia that began about 55 million years ago and which continues unabated today.

这一引人注目的地域范围,比喜马拉雅山更加陡峭,是处于西藏东部边缘的朝上翻的边框地带。响应启始于约5500万年前的、缓慢的但却不可阻挡的印度与亚洲地壳板块碰撞,高原已上升至五千米,这种碰撞持续至今,毫无衰退。