类生物碱类

Aim To study the relationship between permeability coefficient and oil/water partition coefficient of 17 alkaloidal drugs.

目的研究生物碱类药物经皮吸收系数与药物油/水分配系数的关系。

Results The relationship between permeability coefficient and oil/water partition coefficient of 17 alkaloidal drugs or drugs containing 2%Azone can be described as following equations.logkp=7.35×10-2-3.079×10-2logk-8.112;logkp(2%Azo)=8.32×10-2-2.68×10-2logk-5.272,respectively.

结果生物碱类药物的经皮渗透系数与药物油/水分配系数的关系式为：logkp=7.35×10-2-3.079×10-2logk-8.112；logkp(2%Azo)=8.32×10-2-2.68×10-2logk-5.272；结论 17种药物的油/水分配系数平均最佳值为2.83，含2%氮酮后的其平均最佳值为3.17。

OBJECTIVE To establish a new TLC method for identification of some active components alkaloids in Rhizoma Arundo donax L.METHODS Rhizoma Arundo donax L.

目的 建立一种可以同时鉴别芦竹根药材中多种生物碱类成分的方法。

RESULTS In the thin-layer chromatogram of Rhizoma Arundo donax L., the spots of the main alkaloids were round, clear, and well separated.

结果 芦竹根药材薄层色谱图中，各主要生物碱类成分斑点圆整、清晰、分离度好。

Establishing experimental animal model of immunized fibrosis could contribute to research on extracellular matri and cytokine. they turns out that the ingredient of Desmodium pulchellum can relieve extra growth and deposit of ECM and adjust the level of relative cytokine, such as TGF-β1 and IFN-γ, benefit to effect of hepatic anti-fibrosis.

结果证明排钱草生物碱类成分能减轻肝纤维化的基本病理改变即减少肝细胞外基质的过度增生和沉积，调节与肝纤维化密切相关的TGF-β1、IFN-γ等细胞因子水平，向着有利于减轻肝纤维化的方向发展。

Berberine, one of the main constituents of the plant Rhizoma coptidis, is a type of isoquinoline alkaloid, reported to have anticancer effects in different human cancer cell lines.

黄连素是黄连主要的结构，是一种异奎啉类生物碱的型式，报告指出在不同的人类癌细胞有抗癌作用。

Berberine is a kind of isoquinoline alkaloid which is extracted from the roots and barks of ranunculacenep plant coptis, berberine is the major component in coptis with a wide range of pharmacological effect.

小檗碱系从毛莨科黄连属植物黄连根和皮中提取的异喹啉类生物碱，为黄连的主要成分，具有广泛的药理作用。

Chapter 2: The binding of Jatrorrhizine and Berberine with human serum albumin was investigated by spectroscopy and the molecular modelling study.

第二章：应用光谱法结合计算机模拟技术对人血清白蛋白与异喹啉类生物碱药根碱、小檗碱的相互作用进行了详细的研究。

The interaction of Jatrorrhizine and Berberine with serum albumin can induce the changes of secondary structure of serum albumin with reduction ofα-helices.

红外光谱和圆二色谱研究表明异喹啉类生物碱的加入引起人血清白蛋白二级结构的变化，降低了血清的α-螺旋结构含量。

Objective To study the solubility of lipo-alkaloids from prepared aconite root(Radix Aconiti Lateralis Preparata) and identify the sources of lipo-alkaloids in Sini Decoction.

目的研究附子中脂类生物碱的溶解性，确定四逆汤中脂碱的来源。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。