类天疱疮

Methods 10 cases of anti-P_(200) pemphigoid sera were collected. The skin sections from 6 cases of recessive dystrophic epidermolysis bullosa were studied with these sera by indirect immunofluorescence.

方法收集了10例抗P_(200)类天疱疮血清，对6例隐性遗传性营养不良性大疱性表皮松解症皮肤切片进行了间接免疫荧光研究。

Results All the 10 anti-P_(200) pemphigoid sera could react with basement membrane zoneof 5 cases of recessive dystrophic epidermolysis bullosa, while epidermolysis bullosa acquisita sera were negative in these skins.

结果发现10例抗P_(200)类天疱疮血清均与5例RDEB皮肤基底膜带反应，而获得性大疱表皮松解症血清对这些皮肤为阴性。

In addition,in a case of recessive dystrophic epidermolysis bullosa, epidermolysis bullosa acquisita sera react with both BMZ and intracytoplasmic deposition of type Ⅶ collagen,while no anti-P_(200) pemphigoid sera showed this reactivi- ty.

另外，在1例RDEB，EBA血清既与BMZ反应又与Ⅶ型胶原沉积部位的胞浆反应，而抗P_(200)类天疱疮血清无此反应。

The ultrastructural localization of the immunoglobulin and complements in diseased skin of several sub-epidermal bullous diseases, including 1 case of Bullous Pemphigoid , 3 cases of Epidermolysis Bullous Acquisita , 1 case of Bullous System Lupus Erythematosus and 2 cases of Linear IgA Bullous Dermatoses , was detected by postembedding immunogold electronmicroscopic technique.

利用直接免疫金标电镜技术同时检测几种表皮下大疱病：大疱性类天疱疮1例、获得性大疱性表皮松解症3例、大疱性SLE1例、线性IgA大疱性皮肤病2例皮损组织中免疫球蛋白和补体〓，比较它们沉积部位和形态的异同，以探讨该技术在鉴别不同表皮下大疱病中的意义。

Bullous pemphigoid is an acquired autoimmune subepidermal blistering disease caused by autoantibodies against bullous pemphigoid antigen 1 (BPAg1, 230kD) and bullous pemphigoid antigen 2 (BPAg2, 180kD).

类天疱疮乃因体內產生对抗BPAg1(BP230)及BPAg2(BP180)的自体免疫抗体所引起的后天性表皮下水疱病变，其好发於老年人族群。

To achieve this, we use bullous pemphigoid as an example of a typical autoimmune disease.

要做到这一点，我们以大疱性类天疱疮作为一个典型的自体免疫疾病样本。

Objective To investigate whether there is a possible pathogenic relationship between bullous pemphigoid and neurological disorders.

目的 探讨大疱性类天疱疮与某些神经系统疾病之间可能存在的相关病理机制。

In the 188 patients with extensive bullous pemphigoid,topical corticosteroids were superior to oral prednisone (p=0.02), with one-year survival rate 76% vs. 58%, disease control at three weeks 99% vs. 91%, and severe complication rate 29% vs.

188位广泛性大水疱性类天疱疮患者中，外用皮质肾上腺类脂醇的效果优於口服prednisone（p＝0.02），二者的年生存率分别为76％及58％，三周疾病控制率分别为99％及91％，而严重并发症发生率则分别为29％及54％。

Feb. 4, 2002 -- People with bullous pemphigoid no longer need to endure the potential side effects of oral corticosteroids, based on a French study reported in the Jan. 31 issue of The New England Journal of Medicine .

2002年2月4日──1月31日《The New England Journal of Medicine》杂志上发表的一篇法国的研究报道，患有大水疱性类天疱疮的患者，不必再忍受口服皮质肾上腺类脂醇所可能导致的副作用。

In a randomized, multicenter trial, 341 patients with moderate or extensive bullous pemphigoid received large doses of high-potency topical corticosteroids -- either topical clobetasolpropionate cream (40 g per day) or oral prednisone (0.5 mg perkilogram of body weight per day for those with moderate diseaseand 1 mg/kg/day for those with extensive disease)-- applied over their entire body.

在此次追踪多中心的试验中，341位中度或广泛性大水疱性类天疱疮患者接受大剂量较强外用皮质肾上腺类脂醇全身治疗──使用外用clobetasol propionate乳剂（40g/日）或者口服prednisone（中度患者0.5mg/千克体重/日，重度患者1mg/千克体重/日）。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。