类化

Establishing experimental animal model of immunized fibrosis could contribute to research on extracellular matri and cytokine. they turns out that the ingredient of Desmodium pulchellum can relieve extra growth and deposit of ECM and adjust the level of relative cytokine, such as TGF-β1 and IFN-γ, benefit to effect of hepatic anti-fibrosis.

结果证明排钱草生物碱类成分能减轻肝纤维化的基本病理改变即减少肝细胞外基质的过度增生和沉积，调节与肝纤维化密切相关的TGF-β1、IFN-γ等细胞因子水平，向着有利于减轻肝纤维化的方向发展。

Based on reviewing of functionalization of saturated carbon by catalytic oxidation with metalloporphyrins and metal phthalocyanines as a mimic of the enzyme cytochrome P-450, two reaction systems of which one was the preparation of 4, 4'-dinitrostilbene-2, 2'-disulfonic acid from 4-nitrotoluene2-sulfonic acid and the other was the preparation of 4, 4'-bis (dimethylamino -diphenyl) phenylmethanol from 4, 4'-bis (dimethylamino-diphenyl) phenyl methane , were specifically studied as carfunctionalization and oxyfunctionalization of saturated carbon.

本文在全面综述金属卟啉和金属酞菁类模拟细胞色素P-450酶催化剂催化氧化饱和碳原子功能化的基础上，选择由4-硝基甲苯-2-磺酸制取4，4'-二硝基二苯乙烯-2，2'-二磺酸和由4，4'-二苯基甲烷制取4，4'-二苯基甲醇两个反应体系进行饱和碳原子碳功能化和氧功能化的具体研究。

In the case of study, the better fittable algorithm of volume visualization is selected in accordance with the analysis of the software.

三维可视化是科学计算可视化和三维GIS密切联系的纽带，本文综述该方面的发展趋势，研究了两大类三维数据场可视化算法：表面拟合方法(Surface-fitting method)和直接体绘制(Direct Volume Rendering，DVR)。

(1)PAL is better entrapped by PAG with a T∶C ratio of 8∶30.(2)PAL immobilized by glutaric dialdehyde on Bio-Gel P-300 is better than by CDC.(3)The best one is the dehydration and redehydration method.(4)Immobilized and permeated PAL active yeast cells are resistant to trypsin digestion and retain its PAL activity.

(1)固定化酶活性采用T∶C比为8∶30明显高于8∶19；(2)以戊二醛将PAL固定于Bio-GelP300优于用DCD固定化的酶；(3)质脂体包被中以脱水再加水法对酶活性影响较少，脂类组成以磷脂酰胆碱：胆固醇：磷脂酰丝氨酸比值7∶2∶1最好；(4)固定化PAL活性酵母细胞能较好地抵抗人工肠液中胰蛋白酶的水解作用，亦能明显降低苯丙氨酸的浓度。

On experimental day , the rats were intratracheally instilled with bleomycin(5mg/kg body weight)or sterile saline, and then treated with the Fluvastain and saline until they were killed .5 rats of every group were executed in 7,14,28,42 day. Immunohistochemistry and Westernblotting were used to measure the expression of TGF-β, ERK_(1/2) p-ERK protein.

本实验利用博莱酶素诱导大鼠肺间质纤维化，以氟伐他汀为代表研究他汀类药物对肺纤维化大鼠模型的干预作用，并通过观察氟伐他汀对ERK信号通路中重要调节酶ERK_(1/2)的表达及活化的影响，探索肺纤维化的信号传导机制，并为临床提供新的治疗思路。

One route was that the amino-groups on the silica gel were transformed to tertiary amines by Eschweiler-clarke reaction that amine-groups react with formaldehyde and methanoic acid to prepare tertiary amines; the silica gel intermediates with tertiary amine groups reacted with chorohydrocarbons to prepare insoluble silica gel quaternary ammonium salt bactericides. Another route was that the amino-groups on the silica gel reacted with excessive chlorohexadecane; the preparing intermediates were quaternized with iodomethane to obtain insoluble silica gel quaternary ammonium salt bactericides.

一条路线是根据埃施韦勒-克拉克(Eschweiler-clarke)胺甲基化反应，进行胺基叔胺化反应，制成带有叔胺官能团的硅胶中间体，此中间体上的叔胺与卤代烷反应生成杀菌活性官能团季铵盐，制成硅胶类水不溶性季铵盐杀菌剂；另一条路线是带有胺反应活性中心的硅胶与过量正氯代十六烷反应，得到的中间体再用碘甲烷季铵化，得到最终产品——水不溶性季铵盐杀菌剂。

The yield reached 67.0% The medicinal and pesticidal activities of a part of the compounds have been measured .

在进行氨基酰化时，论文克服了该类嘧啶环上4位氨基在常规条件下不与芳香类和带有强吸电子基如三氯乙酰基酰化试剂发生反应的困难，通过采用在强碱性条件下进行酰化，得以成功。

Water margin,that a work dedicated to masculine has always been highly appreciated.yet,it is beyond any doubt that the book presents a biased and even unjust feature of the feminine .there are few women personages in water margin which can be divided into two kinds briefly: namely "lady of easy virtue" and "heroine".novel go on two extremes overly that women'figure was denied impersonal role maid image mould either "bad" or reach "manlike " so that they cant cross to two description of woman these because the writer was intended or involuntary to describe them these.consequently the women' figure maked untrue exceedingly as to the lady of easy virtue write it to the limit excessively ruthlessly poisonously ; as for heroine write its walk chivalrous and loyal to the limit that the woman wasn't defeated by men.the female extreme image was pointed out that the intention of author come from the influence of the super male consciousness to a certain extent and it is inevitability because of masculine being in charge of linguistical power ,in fact, the appearance of women was just only minor role in order that the hero world need to regard man as the centre too.in a word womens destiny in water margin is a miserable foregone!

水浒传》是1部以描写男性英雄为主的名著，历来受到较高评价。然而，作品在女性形象塑造时存在的偏颇甚至不公正却是毋庸置疑的。《水浒传》中的女性人物屈指可数，主要可分为两大类：1是所谓的荡妇恶婆；2是所谓女英雄。作家在对这两类型女性的描写时，都因作者有意或无意的女性意识而走向极端化，实际上是走上了两个无法交汇的极端，使女性形象的塑造过于偏激，不是&淫恶&到极端，就是&男性化&到极点，写淫妇恶婆，写尽其淫，狠，毒；写女英雄，则写尽其行侠仗义，巾帼不让须眉。这种极端化的女性角色定位，既是作者男权意识的自然反映，又是男权社会男性话语权的必然呈现，说白了，出现在《水浒传》的女性不过是点缀和突出男性的生活，是为表现父权制男性英雄世界服务的。

E. thickness of the copper wire wall, length of the single conductor wire, height of the solenoid, the exciting current and the current density, the working temperature of the conductor, time of exciting and demagnetizing, the cooling water pressure and flux density, etc..

所建立的数学模型包含3个目标函数（即能耗极小化目标函数、铜耗极小化目标函数和纯铁用量极小化目标函数）、7个设计变量（即铜管规格参数a、b、t，线圈匝数N〓、N〓，铁铠磁通密度B〓和冷却水压p）和8类14个约束条件（即铜管壁厚、单饼导线长度、螺线管高度、激磁电流与电流密度、导体工作温度、激退磁时间，冷却水压和铁铠磁通密度等约束条件）。

The application results from fluorination showed microwave heating could accelerate chemical reactions markedly. The reaction time could be shortened 50% at least than that of conventional heating. The relationship between fluorinating agents\' structure and their activity was studied systematically. In addition, an anhydrous KF with higher activity was prepared by using expansion effect of microwave heating. As we known, solvents were very important to reaction. The comprehensive study showed some less polar aromatic solvents could be used as dipolar solvents. In addition, they had better effect than dipolar solvents in some occasions, such as fluorination of chlorobenzaldehydes and chlorinated diphenyl ketones etc. The primary applications of ionic liquids were also studied which indicated reactions with ionic liquids as solvents were more efficient and simple.

研究表明，微波是一种节能高效的加热方式，在微波作用下的卤素交换氟化反应具有反应速度快、转化率高、选择性好的优点，其反应时间可较常规加热缩短50%以上；同时也系统地研究了氟化剂种类及制备方式对其反应活性的影响，并利用微波加热的膨化作用制备出了一种活性较高的KF，其活性与喷雾干燥KF相差不大；溶剂对反应具有重要的作用，在此系统地研究了强极性非质子溶剂和中等极性非质子溶剂的应用情况，发现一些中等极性的非质子溶剂如硝基芳烃和氯代芳烃类溶剂在氯代苯甲醛类化合物的氟化反应中具有比强极性非质子溶剂更好的使用效果。

What would he tell Judith and the children?

他将怎样告诉朱迪丝和孩子们呢？

I this is at that time, the opinion with peacockish true girl is full of in a heart.

这就是当时的我，一个心中布满虚荣的女孩子真实的想法。