类似物

Based on the analysis of structure-activity relationships of Linezolid analogues, four new compounds were designed and prepared.

在对利奈唑酮类似物构效关系进行分析的基础上，设计合成了四个未见文献报道的目标化合物。

To date over 1000 synthetic analogues have been prepared.

迄今已超过1000合成类似物准备。

Comparable experiments employing p-toluenesulfonyl azide demonstrated thereaction specialty of fluoroalkamesulfonyl azides.

在同其碳氢类似物如对甲苯磺酰叠氮的对比实验中，还进一步证明了氟烷基磺酰叠氮的反应特殊性。

Results: The polyamine analogue BENS markedly inhibited the proliferation of B16-F1 cells in a dose-dependent manner.

结果：多胺类似物BENS能显著抑制B16-F1细胞增殖，抑制率呈药物浓度依赖性。

The polyamine analogue BENS inhibits growth and induces apoptosis of melanoma B16-F1 cells.

多胺类似物BENS抑制黑素瘤B16-F1细胞生长，并能诱导该细胞凋亡，具有潜在的临床应用价值。

We selected Streptomyces strain FXJ2.014 with high bioactivity for further analysis and found additional metabolites in fermentation extracts of cocultures of strains FXJ2.014, FXJ1.296 and AS 4.1252 respectively with B. subtilis. Quinomycin A was the main bioactive metabolite produced by the monoculture of strain FXJ2.014, while a new quinomycin-like component named FXJ2.014-HB was produced when strain FXJ2.014 was cocultured with B.

发现FXJ2.014、FXJ1.296、AS 4.1252三株菌与枯草芽孢杆菌共培养时产生其在相同条件下单培养时没有的物质，其中链霉菌FXJ2.014单培养时主要产生醌霉素A，共培养时产物中增加了醌霉素结构类似物FXJ2.014-HB。

Research activities also include synthesis and modification of biological-relevant intermediates, cofactors and their corresponding analogs, for elucidation of enzymatic mechanisms.

具体内容包括生物催化体系关键中间体和辅助因子及其类似物的化学合成和修饰；生物催化体系的重建；酶催化反应的机理和生物催化剂工程等。

Nucleoside analogs can decrease virus production by inhibiting the viral polymerase; however, complete clearance by these drugs is not common because of the persistence of the HBV episome.

核苷类似物可能通过禁止病毒聚合酶减少病毒生产；然而，完全清除由这些药物不是共同的由于HBV的坚持episome。

The enzyme tannase, which is used in the present invention, is known to hydrolyse the galloyl ester linkages of polyphenolic substrates such as tannic acid, tea polyphenol gallates, and the like.

我们知道，这种在本发明中所使用的丹宁酶，可水解多酚酸类物质的棓酸酯键，如丹宁酸，茶叶的棓酸多酚酯及其类似物。

Manycompounds, including glycosyl phosphates and their analogues were used as "tools" instudying the mechanism of the enzymes and new drugs.

为了研究酶的作用机理，寻找高效低毒药物，人们对糖基磷酸酯类物质及其类似物进行了广泛的研究。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。