类似物

Results 4 patients in the 5 patients were treated with interferon or nucleoside analogue else at the same time of taking telbivudine ;1 patients took multiple doses of telbivudine ; their clinical presentation are all muscular soreness 、general hypodynamia; one case presented myocardium injury, three cases presented nerve damage.The serum creatine kinase elevated.

结果 5例病人中，有4例合并应用干扰素或其它核苷类似物，1例服用剂量加倍；临床均表现为肌肉酸痛，全身乏力；心肌受累者1例；有神经损伤者3例；血清CK水平升高，临床误诊率高。

Abstract〕 Objective To explore the clinical outcomes of intravesical instillation resiniferatoxin forthe treatment of patients with overactive bladder in female.

目的：探讨膀胱灌注辣椒辣素类似物治疗女性膀胱过度活动症的临床效果。

In this analogue, the hydrogen of amide group could still form a hydrogen bond with the oxygen of ester bond and the ester bond was isosteric with peptide bond.

我们合成了甜味肽的类似物L-天冬酰氨酰-L-α-羟基苯丙酸甲酯，将甜味肽的天冬氨酸替换为天冬酰胺，肽键替换为酯键。

The characters of crude extracellular laccase from Lenzites tricolor were studied.

并通过正交实验研究了碳源、氮源、木素类似物以及初始pH值对该菌产胞外漆酶的影响。

Limonoids, mainly found in the Rutaceae and Meliaceae families,are a group of chemically related triterpene substances and derivatives of secondary metabolism of plants.

柠檬苦素类似物主要存在于芸香科和楝科植物中，是一类三萜类的物质，是植物次生代谢产物之一。

Originally limited to dialkylamino methylenation, the application of Mannich reaction has been expanded much further in recent years to a wide variety of monosubstituted amines, amine equivalents and amides. In addition, a variety of Aza-Mannich and Mannich-Michael methodologies have emerged.

最初该反应的应用范围仅局限于二烷基胺亚甲基化反应，近年来才得到了长足的发展，其研究范围扩展到单取代的胺、胺的类似物以及酰胺等化合物，并发展形成Aza-Mannich和Mannich-Michael等复合Mannich反应。

A series of compounds Bl-B7 have been synthesized as the analogues of Yuehchukene and Murrapanine, the alkaloids isolated from Murraya species.

合成了一系列九里香生物碱月橘烯碱和Murrapanine的类似物B1-B7，并对其进行了表征。

Though the molecular mass and the hypoglycemic activity of myristic acid modified HIDesB30 are both consistent with Detemir, the expression system, purification artwork and the methods of modification were different from Detemir.

本研究实现了含短C肽的人胰岛素原类似物HMPIDesB30在毕赤酵母中的高效分泌表达，表达量达1 g/L，分泌表达的重组蛋白HMPIDesB30未出现糖基化，未形成二聚体和多聚体，并具有生物学活性。

Based upon the synthetic procedure, we can rationally modify the molecular structure of CsO to screen out the more active and less nephrotoxic peptidomimetics.

在 CsO 的化学合成的基础上，我们可以进一步通过结构活性关系研究来筛选出活性更高、毒性更小的多肽类似物。

The McAbs subtype was IgG1.The ascite titer was 10-7.The McAbs had no cross-reaction with some analogues of nitroaniline.

该抗体亚类为IgG1，制备的单克隆抗体腹水效果评价达10-7，与其他硝基苯胺结构类似物无交叉反应。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。