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管细胞

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The main injury of kidney was located in proximal tubular epithelial cell ,it peaked at 12 hours and 24 hours after reperfusion,the sporadic karyopyknosis and karyorrhexis could be seen,but the basement membrane preserved well.48 hours later,the restoration could be seen.7 days later it restored obviously.

肾脏损害主要以近曲肾小管上皮细胞为主,12h、24h损伤达到高峰,可见核固缩、核碎裂,但基底膜保留完好。48h开始出现修复现象。7d后明显修复。

Nineteen spots were changed significantly after FA treatment.Thirteen proteins were identified by peptide mass fingerprinting or peptide sequence analysis,including putative nucleoside diphosphate kinase,elongation factor 1-gamma,triosephosphate isomerase,60S acidic ribosomal protein P0,heat shock protein 75 kDa,similar to heat shock 70kD protein binding protein,annexin I,hypothetical protein FLJ34423,microtubule-actin crosslinking factor 1,lamin B2,ATP synthase alpha chain,mitochondrial precursor,proteasome subunit alpha type 6.These identified proteins involved in energy metabolism,translation and RNA processing,protein folding,redox regulation,cell structure and cell signaling.

双向凝胶电泳结果显示,甲醛刺激后19个蛋白斑点发生变化,肽指纹图谱及肽序列标签鉴定了其中13个蛋白斑点,已鉴定的蛋白包括二磷酸核苷酸激酶、延长因子1-γ,磷酸丙糖异构酶、60S酸性核糖体蛋白P0、75kDa热休克蛋白、70kD热休克蛋白样结合蛋白、钙依靠磷脂结合蛋白I、假想蛋白FLJ34423、微管-肌动蛋白交叉连接因子1、核纤层蛋白B2、ATP合成酶α链、蛋白酶体α亚基6,这些蛋白功能涉及转录调节、蛋白折叠、信号传导、能量代谢、细胞骨架等各个方面。

Thirteen proteins were identified by peptide mass fingerprinting or peptide sequence analysis,including putative nucleoside diphosphate kinase,elongation factor 1-gamma,triosephosphate isomerase,60S acidic ribosomal protein P0,heat shock protein 75 kDa,similar to heat shock 70kD protein binding protein,annexin I,hypothetical protein FLJ34423,microtubule-actin crosslinking factor 1,lamin B2,ATP synthase alpha chain,mitochondrial precursor,proteasome subunit alpha type 6.These identified proteins involved in energy metabolism,translation and RNA processing,protein folding,redox regulation,cell structure and cell signaling.

双向凝胶电泳结果显示,甲醛刺激后19个蛋白斑点发生变化,肽指纹图谱及肽序列标签鉴定了其中13个蛋白斑点,已鉴定的蛋白包括二磷酸核苷酸激酶、延长因子1-γ,磷酸丙糖异构酶、60S酸性核糖体蛋白P0、75kDa热休克蛋白、70kD热休克蛋白样结合蛋白、钙依赖磷脂结合蛋白I、假想蛋白FLJ34423、微管-肌动蛋白交叉连接因子1、核纤层蛋白B2、ATP合成酶α链、蛋白酶体α亚基6,这些蛋白功能涉及转录调节、蛋白折叠、信号传导、能量代谢、细胞骨架等各个方面。

Aim and Methods: In 36 anesthetized spontaneously breathing Sprague-Dawley rats, the types of respiratory neurons and the state of neurotransmitters and receptors in nucleus paragigantocellularis lateralis were studied with extracellular recording technique and multibarrel microelectrode techniques.

目的和方法:用细胞外记录法和多管微电极微电泳法在 36只麻醉自主呼吸的SD大鼠,系统探查旁巨细胞外侧核尾半侧呼吸神经元的类型及该区的递质受体情况。

VLDL can downregulate the expression of the hOAT1gene possibly induced by lipodystrophy easily acting with hyperuricemia.

VLDL可下调hOAT1mRNA的表达,可能与脂代谢紊乱易合并高尿酸血症有关。脂蛋白类,VLDL;尿酸;肾小管;细胞,培养的;基因表达

ResultsCompared with those in the control, urine volume was decreased markedly, plasma AVP and cAMP levels in renal medullar tissue were decreased obviously, and AQP2 expression was decreased significantly in model group.

结果与对照组相比,模型组大鼠的尿量明显增加,血AVP和肾髓质cAMP水平下降,集合管上皮细胞AQP2表达减少。

Results: All the slides of the breast carcinoma in our department were reviewed, 9 cases of glycogenich, clear cell carcinoma, 4 cases of mucinous carcinoma, 2 cases of tubular carcinoma, 18 cases of metaplastic carcinoma, 6 cases of apocrine carcinoma, 1 case of secretary carcinoma, and 2cases of lipid-rich carcinoma were found.

结果:回顾42例乳腺癌病理切片,发现富含糖原的透明细胞癌9例,黏液癌4例,小管癌2例,化生性癌18例,大汗腺样癌6例,分泌型癌1例,富脂质癌2例;不同组织类型的乳腺癌具有不同的光镜、特殊染色及电镜表现。

Objective To investigate the clinicopathologic features, immunotype, differential diagnosis and prognosis of renal mucinous tubular and spindle cell carcinoma.

目的 探讨肾脏黏液样小管状和梭形细胞癌的临床病理特征、免疫表型、鉴别诊断及预后。

To elucidate the effect of p -nonylphenol on cytochrome P450 aromatase (P450arom) gene and Mullerian inhibiting substance gene in fish gonad, exploring the mechanism of its estrogenic action.

研究壬基酚(P—nonylphenol,NP)对细胞色素P450芳香化酶基因(P450arom)和苗勒氏管抑制物基因表达的影响,探索其对鱼类雌激素样作用的分子机制。

A few muscle stem cells exist in adult mammalian skeletal muscle. Muscle stem cells can be activated to initiate proliferation and give rise to spindly myoblasts, which undergo differentiation and cell fusion into multinucleated myotubes.

哺乳动物骨骼肌中存在着少量的肌肉干细胞,肌肉干细胞可激活、增殖形成单核的成肌细胞,并融合分化为多核肌管。

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