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管细胞

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Between P14 and P21,CIAPIN1 immunoreaction in the brain,heart and liverbecame much lower. However,between P21 and P28,CIAPIN1 immunoreactionin the heart,brain,liver and skeletal muscle became much lower,while with thekidney development,CIAPIN1 immunoreaction in the kidney became higher. Invarious tissues from adult mouse,CIAPIN1 immunoreaction could be seen incardiac muscle cell,brain,hepatocyte,epithelium of renal tubule,skeletal muscle,lung tissue,gastric mucosa and gland,acinus lienalis.2. Distribution of CIAPIN1 in normal fetal and adult human tissuesTo reveal the possible physiological role of CIAPIN1,we examined theexpression and distribution of CIAPIN1 in fetal and adult human tissues usingimmunohistochemistry. We found that CIAPIN1 was ubiquitously distributed infetal and adult tissues,and was localized in both the cytoplasm and the nucleus.

然而,在3个月大的成年鼠中,CIAPIN1阳性反应物在心、脑、肝和肾小管中的表达强度要低于P28小鼠;但CIAPIN1阳性反应物在成年鼠骨骼肌中较P28小鼠高。2、CIAPIN1蛋白在人5个月胚胎及成人多器官组织内的表达在人5月胚胎多器官组织中,CIAPIN1阳性反应物见于心脏、胆囊单层柱状上皮和粘膜、结肠粘膜、小肠粘膜和绒毛、肝脏、直肠腺体、胃粘膜、肾上腺束状带、甲状腺滤泡、脾索、胸腺小叶间隔、皮肤真皮层和汗腺、睾丸白膜和间质、脑组织内神经元和神经胶质、肺小支气管和肺泡、骨骼肌、肾脏皮髓质和肾小管、子宫内膜、胰腺腺泡和胰岛、卵巢、输卵管粘膜等绝大多数组织细胞。

Results: The incidence of cryptorchidism of male offsprings in group C and D was 10.8% and 63.5% respectively. The organ/weight of cryptorchid testis and epididymis significantly decreased compared with the control. Abnormal pathological and micro-structural alternations of seminiferous epithelium and sertoli cells were also observed.

结果:C、D组雄仔鼠隐睾发生率为10.8%和63.5%;隐睾睾丸、附睾的脏器系数显著减轻;睾丸生精上皮萎缩,生精细胞层减少甚至消失,曲精小管体积减小;同时附睾管腔中精子缺如。

Over-expression of NaDC3 accelerates the speed rate of energy metabolism and increases intracellular ROS generation by transporting an overdose of tricarboxylic acid cycle intermediates in human renal tubular epithelial cells.

NaDC3过表达可通过转运过多的三羧酸循环中间代谢产物进入细胞内而加快肾小管上皮细胞能量代谢的速率、增加细胞内ROS的产生水平。

In this study, we found that the positive immunostaining for αSMA was increased in group DN from week 4 onward, mainly located in dilated tubuli, which was more evident at week 8. The double staining for CTGF and p27kip1 showed that the increased positive staining for both antibodies was more evident in tubuli and some glomeruli.

正常大鼠肾脏可以有少量细胞P27kip1染色阳性,本研究发现,在DN模型组,第1周起肾小球和肾小管P27kip1染色阳性细胞即显著增加(P<0.01),且随着病程进展,P27kip1染色阳性细胞比例显著增加。

On the basis, silkworm vasa gene has been studied by in situ hybridization on gonads.

结果表明,家蚕vasa基因在幼虫期只在生殖系相关的细胞和组织中表达(如精原细胞,精囊,卵巢管等),而在其它组织细胞中不表达。

Cells expressing stem cell markers, including GFAP, and proliferation markers are closely apposed to the laminin-containing extracellular matrix surrounding vascular endothelial cells.

表达干细胞标记物(包括GFAP以及增生标记物)的细胞紧密结合在脉管内皮细胞周围含有层黏连蛋白的细胞外基质上。

Essel formation in itro was inhibited with mAbs against TNF-alpha, which, when secreted by cocultures of melanoma cells with human monocytes, induced endothelial cells under collagen gels to form branching, tubular structures.

在体外,TNF-alpha单抗能抑制血管形成,而当肿瘤细胞与单核细胞共培养时能分泌TNF-alpha,使胶原下的内皮细胞形成分枝和管状结构。

Results: The animal experimental model indicates the facial nerve' s bone canal fracture can make the facial nerve hyperaemia, strut, and putrescence, denaturalization and with the Schwann cell and the cell become more and more, taking on the restore evidence.

结果 动物实验表明:面神经骨管骨折后,面神经发生充血肿胀,并出现脱髓鞘、变性及坏死的变化,伴随神经损伤的同时出现巨噬细胞和施万细胞增生肥大及纤维母细胞的增生,呈现修复迹象。

In the SMC of the normal rabbits, myofilaments and macula densa were abundant, few mitochondrla and endoplasmic reticulums were found around the nuclear, and the SMC was in the contractive stage. In the SMC of the model rabbits, few myofilaments and macula densa were found, rough surfaced endoplasmic reticulums and mitochondria were abundant, some phagocytosed much lipid and became foam cells, the SMC was in the synthetic stage.

实验12周,高脂组家兔主动脉斑块面积百分比为47.69±12.84%,内膜斑块厚度为0.68±0.08mm,内膜斑块横断面积与中膜面积比值为1.28±0.35;内膜脂质斑块弥漫且较厚,有大量的泡沫细胞堆积,可达8~10层,管腔直径变小,内膜不光滑;泡沫细胞内富含脂滴,呈椭圆形气球样,有的斑块中可见显著的平滑肌细胞增生及大量的弹力纤维形成。

Microtubules play important roles in many essential cell functions including mitosis, intracellular transport, positioning of membrane-bounded organelles, and cell shape.

微管在细胞的许多过程中发挥着重要作用,如有丝分裂、胞内运输、膜围细胞器的定位以及细胞形态保持等等。

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