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In the preformulation study, the ultraviolet spectrum and HPLC methods for the assay of α-asarone were established firstly and then the physicochemical properties, especially the octanol/water partition coefficient and the solubility in various solvent systems such as alcohol, PEG 400, IPM, octanol were examined. The prediction permeability was then compared with actual transdermal parameters obtained from the in-vitro diffusion study , and feasibility of drug transdermal absorption was then analyzed.

在制剂开发的处方前研究工作中,首先建立了α-细辛醚的紫外及HPLC分析方法,测定了药物的油水分配系数及在生理盐水、各系列浓度的乙醇、PEG400、肉豆蔻酸异丙酯、正辛醇等溶媒中溶解度;其次,确立了药物体外经皮渗透研究的方法,并考察溶媒及促渗剂(乙醇、丙二醇、肉豆蔻酸异丙酯等)对药物体外经皮渗透性能的影响,计算药物经皮渗透的各参数,根据药物的药物动力学参数,分析了药物经皮吸收的可行性。

Due to big carrier concentration and optical band gap, transparent conductive oxide thin films exhibit outstanding optical and electrical properties, such as low resistively and high transmittance in the visible range etc.

透明导电氧化物薄膜材料具有大的载流子浓度和光学禁带宽度因而表现出优良的光电特性,如:低的电阻率和高的可见光透过率等。目前,此类材料体系包括In_2O_3、SnO_2、ZnO及其掺杂体系In_2O_3:Sn、SnO_2:Sb、SnO_2:F、ZnO:Al等。

The optimal harvest time,preserving the green,boiling and technique of preserving the brittleness of Mongolia Scorzonera was studied.

研究了蒙古鸦葱的采收时机,护绿、烫漂和保脆技术,实验表明:选择叶龄在18~20d采收,在浓度为0.2%的稀碱溶液中浸泡30min保绿,烫漂温度98℃、时间叶柄1.5min、叶片0.5min,在烫漂液中加入0.15%的氯化钙保脆等措施,解决了产品速冻时的褪色、质地变软等问题。

The preparation of avermyctin emulsions in water was achieved by mixing the surfactants polyoxyethylene (10) octylphenyl ether (OP10), polyoxyethylene styrenated phenol ether (602), and polyoxyethylene (40) castor oil ether (EL-40) with polyoxyethylene (20) castor oil ether (EL-20), separatively. Emulsion stability was investigated by analyzing the hydrophile-lipophile balance, critical micelle concentration, and surface tension. Then, the surfactants of polyoxyethylene polyoxypropylene styrenated phenol ether (1601), block copolymer (L64), and octyl phenyl polyoxyethylene phosphonate were added to the emulsion made by blending EL-40 and EL-20, separatively. The stability of the emulsions was investigated further and discussed in terms of droplet size, surface tension, and zeta potential.

首先将辛基酚聚氧乙烯醚(OP10)、苯乙烯基酚聚氧乙烯醚(602)和蓖麻油聚氧乙烯(40)醚(EL-40)分别与蓖麻油聚氧乙烯(20)醚(EL-20)复配制备阿维菌素水乳剂,从亲水亲油平衡值、临界胶束浓度、表面张力等方面分析了二元表面活性剂复配对乳液稳定性的影响;其次,在EL-40与EL-20复配基础上,将苯乙烯基酚聚氧乙烯聚氧丙烯醚(1601),嵌段共聚物(L64)和辛基酚聚氧乙烯醚磷酸酯分别添加到乳液中,从粒径、表面张力和zeta电势等方面考察三元表面活性剂复配对乳液稳定性的影响。

By using microcalorimetric method, the growth thermogenetic curves of Rhizopus nigricans inhibited by four kinds of heavy metal ions are determined, parameters such as growth rate constants k, inhibitory ratio I, and half inhibitory concentration IC 50 etc.

用微量热法测定了Cu~(2+),Cd~(2+),Hg~(2+),Pb~(2+)等四种重金属离子对黑根霉菌生长抑制的产热曲线,得到了黑根霉菌在不同条件下的生长速率常数k,抑制率I,半抑制浓度IC_(50)等参数。

Abstact:In the thesis the rheology of trigonella bean gum was studied by studying the apparent viscosity changing affectedby concentration, shearing, temperature, pH, freazing-thawing and synergic effect with xanthan gum.

通过测定和分析浓度、剪切力、温度、pH和冻融等变化对葫芦巴胶溶液表观粘度的影响及与黄原胶等食品胶的协效性,对葫芦巴胶溶液的流变性进行了研究。

Chapter three is the degradation of Abamectin in soils. The results show:(1) The decomposition of Abamectin is fastest in Aquic Cambosols while slowest in Udic Cambosols in five kinds of different soils.(2) Organic matter content in soil is the most important factor which influences the degradation half-life of Abamectin in soil, and their relative coefficient arrives at 0.9323, but pH value, total nitrogen, CEC and field maximum moisture capacity correlate little.(3) Soil organic matter, soil temperature and pesticide concentration can obviously affect Abamectin degradation in soil, in addition, the degradation half-life of Abamectin in sterilized soil is far more than that in non-sterilized soil, which maybe contributes to microorganism in soil. Chapter four is the microbial degradation of Abamectin.

第三章研究了阿维菌素在土壤中的降解,结果表明:(1)五种不同类型土壤中,阿维菌素在潮湿雏形土中降解最快,而在湿润雏形土中降解最慢;(2)土壤有机质含量与阿维菌素半衰期相关性较强,相关系数为0.9323,而土壤酸碱度、总氮含量、阳离子交换量和田间最大持水量等因子与阿维菌素半衰期相关性较小,说明影响阿维菌素在土壤中降解的最主要因子为有机质含量;(3)土壤有机质、土壤温度和农药浓度等因素对阿维菌素在土壤中的降解有较大影响,此外灭菌条件下其降解半衰期远大于未灭菌时的半衰期,这表明阿维菌素在土壤中的降解可能和土壤微生物有关。

The result shows that when HPLC adopts 254 nm as scan wavelength, and the mixture of acetonitrile and water according to appropriate proportion as flowing phase, the parameters such as accuracy, repetition and precision et al for the method are all good to satisfy the essential rules of pesticide residue determination.Chapter three is the degradation of Abamectin in soils. The results show:(1) The decomposition of Abamectin is fastest in Aquic Cambosols while slowest in Udic Cambosols in five kinds of different soils.

第三章研究了阿维菌素在土壤中的降解,结果表明:(1)五种不同类型土壤中,阿维菌素在潮湿雏形土中降解最快,而在湿润雏形土中降解最慢;(2)土壤有机质含量与阿维菌素半衰期相关性较强,相关系数为0.9323,而土壤酸碱度、总氮含量、阳离子交换量和田间最大持水量等因子与阿维菌素半衰期相关性较小,说明影响阿维菌素在土壤中降解的最主要因子为有机质含量:(3)土壤有机质、土壤温度和农药浓度等因素对阿维菌素在土壤中的降解有较大影响,此外灭菌条件下其降解半衰期远大于未灭菌时的半衰期,这表明阿维菌素在土壤中的降解可能和土壤微生物有关。

The factors of temperature and humidity influenced on film thickness and order of layer were studied, in which pulling speed and pulling times were also included. It showed that the thickness of single dip-coating film reached 0.23 μm ~ 0.625 μm, and the degree of order of surface layer were still holding much higher.b Adopting calcined or uncalcined mesoporous silica membrane as matrix, nano zirconia particles were assembled through ion exchange method and ion-template exchange method.

结果表明,单次提拉膜膜厚0.23μm~0.625μm、8次提拉后表层膜仍有一定的有序性; b以自制的介孔氧化硅煅烧/未煅烧厚膜样为基体,采用离子交换法/离子模板交换法组装锆氧纳米粒子,选用DSC-TG、FT-IR、Uv-vis、SAXRD等对不同组装方法、锆源浓度、pH值等组装条件下ZrO_2/介孔氧化硅厚膜组装效果进行评价。

The ISSR fingerprinting of 18 Japanese plum cultivars and 12 plum species or variety were established by using optimum system with primer 5"-9T-3"and 5"-9C-3", respectively. The identification rate of plum cultivars and species or variety was 100%. The effects of five important components on reaction of SSR were studied with Prunus salicina cv. Meilili. The results showed that the optimum concentration of five important components i.e. Tag DNA polymerase, Mg +, single primer, template DNA and dNTPs in 25 μL reaction system of SSR were 1.5u, 2.0mM, 0.8 μ M, 30~40ng and 0.16~0.24mM, respectively. The dendrograms of these cultivars was contructed according the Jaccard coefficient of similarity.

利用该优化体系,以5′-_9T-3′为引物,构建了中国李18个品种的ISSR指纹图谱,该引物可将这些品种完全区别开来;以5′-_9C-3′为引物,构建了李属6类种质资源的ISSR指纹图谱,该引物区分率为100%。4、中国李品种适宜的SSR反应分析体系是:25μL SSR反应体系中,Taq DNA聚合酶、Mg~(2+)、每个引物、模板DNA和dNTPs等5种成分的适宜浓度分别是:1.5u、2.0mmol·L~(-1)、0.8μmol·L~(-1)、30~40ng和0.16~0.24mmol·L~(-1)。5、采用RAPD、ISSR和SSR等三种分子标记技术对中国李品种资源54份和2个欧洲李品种进行了遗传多样性分析,并以品种间的遗传相似系数构建了Jaccard聚类树状图。

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推荐网络例句

Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在,'歼灭战perfuming自己与胡努特,那麼,他来到和SAT 。

The shamrock is the symbol of Ireland and of St.

三叶草是爱尔兰和圣特里克节的标志同时它的寓意是带来幸运。3片心形叶子围绕着一根断茎,深绿色。