等时性的

Infusion of theChinese prescription "Ying-chen dandao tang" in 28 cholelithiatic patients who had had cholecystectomy choledochotomy with a "T" tube drainage (15 cases in experimental group and 13 cases in control group).

发现，在胆酸丢失、胆汁成石指数增高、胆汁成石性增高的情况下，应用该制剂时，胆汁成石指数无明显变化；并且胆汁中总胆红素、非结合胆红素浓度及胆汁UCB/T Bil％值等均较注药前明显降低。

The sort and reason of grinding burn were analyzed. Based on the characteristic of the coned shape grinding wheel, the fac-tors of affecting the depth of the thermal damage layer were found.

锥面砂轮磨齿机工作时，由于工件受热和冷却、膨胀和收缩等不均匀性及磨削过程中各种变化因素的作用，极易产生磨削裂纹和烧伤。

Mechods The clinical data of12cases suffering from isolated sphenoid sinus lesions were analyzed retrospectively and the correlated documents reviewed.Results All the12cases were preoperatively diagnosed by CT,MRI,and intranasal endoscopy.The postoperative pathology showed7cases with sphenoid sinustis,2cases with submucous cystis,3cases with mycosis.

蝶窦位于颅底，解剖位置深在，部位隐蔽［1］，由于蝶窦病变早期临床表现缺乏特异性，单纯前鼻镜额镜检查时因受照明，角度等影响，无法窥清蝶窦及蝶窦开口的病变情况，因此，孤立性蝶窦病变临床误诊率较高。

The cardiac effects of Ado are negative chronotropic; dromotropic; inotropic and coronary vasodilation which serves as a negative feedback regulator in the cardiovascular system in order to rectify the oxygen supply/demand imblance.

以负性变时、变导、变力及扩张冠脉等作用对心血管系统发挥负反馈调整效应，维持心肌氧的供需平衡。

Results The negative correlations were found on the Glasgow Outcome Scoreto the items such as conscious state at admission,Glasgow Coma Score,psychiatric symptoms,hemiplegia,Babinski sign,abnomal degree of Electroencephalogram,focal lesions found by neuro-image investigation and mean peak flow velocityand pulsatility indexof basilar artery and vertebral arteries by transcranial Doppler ultrasonography investigation;The non-correlation was found on the Glasgow Outcome Score to theitems such as headache,febrile,epilepˉsia style,the involvement of cranial nerve,dystaxia,neck stiffness,Cerebrospinal fluid investigation and blood serum enzymology.

结果 入院时的意识状态、GCS、精神症状、偏瘫和/或偏身感觉障碍、巴彬斯基征以及脑电图异常程度、影像学所见的病灶范围、基底动脉和椎动脉的平均峰流速、脉动指数和Glasgow预后评分呈负相关；头痛、发热、癫痫类型、颅神经受累情况、共济运动、脑膜刺激征、脑脊液检查（含压力、蛋白定量、细胞数、HSV-PCR）以及血清酶学的变化和Glasgow预后评分之间无相关性。结论入院时的意识状态、GCS、精神症状、局灶性神经系统体征以及脑电图异常程度、影像学所见的病灶范围、后循环的血管痉挛程度和血流阻力等是影响病脑预后的主要因素。

Results The negative correlations were found on the Glasgow Outcome Scoreto the items such as conscious state at admission,Glasgow Coma Score,psychiatric symptoms,hemiplegia,Babinski sign,abnomal degree of Electroencephalogram,focal lesions found by neuro-image investigation and mean peak flow velocityand pulsatility indexof basilar artery and vertebral arteries by transcranial Doppler ultrasonography investigation;The non-correlation was found on the Glasgow Outcome Score to theitems such as headache,febrile,epilepˉsia style,the involvement of cranial nerve,dystaxia,neck stiffness,Cerebrospinal fluid investigation and blood serum enzymology.

结果 入院时的意识状态、GCS、精神症状、偏瘫和/或偏身感觉障碍、巴彬斯基征以及脑电图异常程度、影像学所见的病灶范围、基底动脉和椎动脉的平均峰流速、脉动指数与Glasgow预后评分呈负相关；头痛、发热、癫痫类型、颅神经受累情况、共济运动、脑膜刺激征、脑脊液检查（含压力、蛋白定量、细胞数、HSV-PCR）以及血清酶学的变化与Glasgow预后评分之间无相关性。结论入院时的意识状态、GCS、精神症状、局灶性神经系统体征以及脑电图异常程度、影像学所见的病灶范围、后循环的血管痉挛程度和血流阻力等是影响病脑预后的主要因素。

Research data was collected by means of interviews with the help of questionnaires, concept maps, instructional videotapes as elucidatory references.

本研究以质性研究方法，采取晤谈方式来探究两位大二职前教师关於教学的想法，并以问卷、概念图、教学录影带等资料作为诠释资料时之参考。

In the light of existent problems, the following suggestions are put forward: The erosion-resisting grouting material and small W/C ratio shall be applied, and the chemical grouts may be used if necessary.

针对存在的问题，提出了防渗灌浆材料应选用抗侵蚀性材料、采用小水灰比浆液、必要时用化学浆液等建议。

The average percentage of polymorphic bands are 72.06% for ISSR and 66.67% for RAPD respectively. The genetic diversity of ginkgo revealed by ISSR (the average effective number of alleles is 1.8780, the average Nei"s gene diversity is 0.4652, and the average Shannon"s information index is 0.6574) are all higher than those by RAPD (the average effective number of alleles is 1.7842, the average Nei"s gene diversity is 0.4317, and the average Shannon"s information index is 0.6211), while the standard errors of the parameters estimated by ISSR were lower. Therefore, ISSR molecular markers are more suited than RAPD molecular markers when testing the genetic diversity of ginkgo populations and determining the genetic relationship of among populations or among individuals which are much similar hereditarily.

本文应用RAPD和ISSR两种分子标记技术，选取中国5个可能的野生银杏居群共计75个样品，对其遗传多样性进行了研究，得出以下结论：(1)用筛选出的12个RAPD引物和10个ISSR引物进行PCR扩增，分别扩增出65条和68条重复性高、清晰的条带，多态性位点百分率分别66.67%和72.06%，ISSR揭示的银杏遗传多样性(平均有效等位基因数目为1.8780，平均基因多样度为0.4652，平均信息指数为0.6574)高于RAPD所得到的结果(平均有效等位基因数目为1.7842，平均基因多样度为0.4317，平均信息指数为0.6211)，其所估算参数的标准差要低于RAPD所估算出的值，因此，在研究亲缘关系非常近的银杏物种的遗传多样性并试图确定居群间或个体间的遗传关系时，ISSR分子标记技术比RAPD分子标记技术更为合适。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。