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The allele frequency of ALDH2*1 between alcoholic cardiomyopathy group and alcohol dependent group was significantly higher than that in controls and the allele frequency of ALDH2*2 between alcoholic cardiomyopathy group and alcohol dependent group was significantly lower than that in controls.

嗜酒组和酒精性心肌病组ALDH2*1等位基因的频率高於对照(P.01),ALDH2*2等位基因的频率低於对照组(P.01)。

Gene frequency The proportion of an allele in a population in relation to other alleles of the same gene.

基因频率:指某一特殊类型的等位基因在群体中所有等位基因总数中所占的比率。

Gene mutations were detected in 25 patients and a 18-year-old girl among 16 families. Trinucleotide repeats of CAG were 73~79. The fragments of abnormal alleles were 380~402bp, and all patients were heterozygous. The copy numbers of normal alleles were 18~40, fragments from 202~270bp. SCV reduction was much obvious compared to MCV, MCV and SCV in lower limb ?ere much more slow than that in upper's. BAEP, VEP were also delayed in latency. The anticipation in parental sex bias were much more obvioius than that in matental's. Cerebellar ataxia was most severe, the next were dysarthria and bulging eyes. Amytrophy was seen only in bed ridden patients. Cerebellar atrophy was more severe than brain stem, cord atrophy was n't observed in all MJD.

结果检出10个家系25例病人及1例症状前18岁女孩有MJD基因突变,CAG三核苷酸重复73~79次,异常等位基因片段长380~402bp,均为杂合子;正常人CAG三核苷酸重复18~40次,等位片段长200~270bp,电生理发现MJD的SCV减慢比MCV明显,而下肢的MCV、SCV又较上肢明显,BAEP、VEP均有不同程度的潜伏期延长或波的异常;MJD的父亲遗传早于母亲,进展也较块,临床以小脑性共济失调为突出症状,其次为构音障碍、突眼等,肌肉萎缩仅见于晚期病人;MRI示小脑萎缩较明显,脑干萎缩并不严重,未见明显的颈髓萎缩。

These were controlled by multiple allels or by loci with allels that segregate independently whereby epistasis also may have played a role.

这些是受复等位基因或含分离等位基因的位点支配的,上位性也可能靠它而起了作用。

Genetic polymorphism and effect of MC4R gene(1) The distribution of genotype is significantly different among 6 breeds.

在外来品种中有更多的等位基因G,在地方品种中有更多的等位基因A。

There were totally 22 alleles of these microsatellite loci, and the number of alleles per locus ranged from 2 to 6. The average homozygosity, average polymorphism information content and average heterozygosity was 41.67%, 0.488 and 0.5833, respectively.

对这6个位点的扩增产物进行分析,结果显示:6个位点共检测到22个等位基因,每个位点的等位基因数从2个到6个不等;平均基因纯合率为41.67%,平均多态信息含量为0.488,平均杂合度为0.5833。

And by applying the linear dispersion relation of wave, all the properties of wave refraction including wave rays, constant phase lines, phase function and crest lines etc., can be expressed in explicit functions. By introducing an orthogonal curvilinear coordinate along the wave ray and the constant phase line, and with an estimated scale factor, the refraction coefficients along any wave ray can then be determined. The present results are verified by ordinary wave ray theory and some previous numerical results.

就此特例情况在波浪的线性分散关係的应用下,前进波浪折射现象的整体特性,包括波向线、等位相线、位相函数与波峰线皆被导述出明確显然的函数表示;同时引入由沿著波向线与等位相线所构成的完全符合波浪折射几何通性的正交曲线座標,求出其尺度因子后,由能通量守衡原则定出沿著任一条波向线上的折射係数;並由之对往昔纯依两相邻的波向线间的几何类比所给定的折射係数给予导証之。

ASCL2 gene escapes genomic imprinting in skeletal muscle,fat, heart,liver,spleen,lung,kidney,stomach,small intestine,uterus,ovary and pituitary.(2) Both of the transcripts of NNAT gene is paternally expressed in skeletal muscle,fat,heart, liver,spleen,lung,kidney,stomach,small intestine,uterus,ovary and pituitary.(3) DIRAS3 gene is paternally expressed in skeletal muscle,fat,heart,liver,spleen,lung, kidney,stomach,small intestine,uterus,ovary and pituitary.(4) DLX5 gene is maternally expressed in skeletal muscle,fat,spleen,lung,stomach,small intestine,but escapes imprinting in heart,liver,kidney,uterus,ovary,testicle and pituitary.

1ASCL2基因在肌肉、脂肪、心、肝、脾、肺、肾、胃、小肠、子宫、卵巢和垂体中均逃脱印记;(2)NNAT基因两个转录本在肌肉、脂肪、心、肝、脾、肺、肾、胃、小肠、子宫、卵巢和垂体中均为母系印记:(3)DIRAS3基因在肌肉、脂肪、心、肝、脾、肺、肾、胃、小肠、子宫、卵巢和垂体中母系印记:(4)DLX5基因在骨骼肌、脂肪、肺、脾、胃和小肠中表达母本来源的等位基因,即表现为父系印记;而在心、肝、肾、子宫、卵巢、睾丸和垂体中表达双亲来源的等位基因,即逃脱印记。3。

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公司主要生产光柱数字式显示变送仪、显示变送报警仪、巡检变送报警仪、智能调节仪、流量积算控制仪、Q、D型操作器、架装式、墙挂式、卡式仪表、闪光报警器、三相可控硅微处理温度控制柜、扩散硅压力/液位变送器、电容式差压/压力变送器、热电偶、热电阻、双金属温度计,现场热工校验装置、自动化成套设备,可广泛地应用于炼油、化工、建材、轻工、冶金、纺织等行业的温度、压力、流量、液位等参数的自动化监测和控制。

Based on this information, offspring from 10 crosses where parents were known were genotyped by the 6 microsatellite loci and used for parentage analysis. The result showed that assignment success of the progeny to their 'true' mother and father was 88% and 78% respectively, which were lower than predicted by the Cervus simulations. This could be explained by the existence of null or mutant alleles and by Taq DNA Polymerase slippage in the microsatellite loci.

在家系混养的模拟实验中使用这6个高多态性的微卫星基因座从20个候选雌虾中找到真正母亲的概率为88%,从30个候选雄虾中找到真正父亲的概率为78%,低于理论预测值,分析可能与微卫星基因座中的无效等位基因,等位基因的突变以及PCR过程中 Taq 酶发生链滑移等因素有关。

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