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Telomerase activation was the samepathway of cellular immortalization and malignant transformation.

端粒酶的活化可能是细胞永生化或恶化的共同通路。

PinX1 is a potent telomerase inhibitor in interphase; however, its function in mitosis is not well documented.

PinX1是一个潜在的间期端粒酶抑制因子,它在细胞有丝分裂期中的报道很少。

The fact that telomere homolog oligonucleotides trigger SOS-like responses and cause selective apoptosis of malignantly transformed cells may provide an important clue to the prevention and treatment of photo-induced skin tumors.

端粒同源寡核苷酸引发SOS反应并导致恶性转化细胞发生选择性凋亡的特点为光源性皮肤肿瘤的防治提供一种新方法。

The vegetative body of the filamentous algae (e.g. Spirogyra), composed of a line of similar cells joined by their end walls.

丝状体:2。丝状藻类的植物体,由一列相似的细胞彼此通过端壁连接而成。

This result suggested that the regulation region could exist in the 5′untranslated region of EG Ⅲ mRNA, which is recognized by the gene expression related factors of S. cerevisiae.

这表明瑞氏木霉的EG Ⅲ基因在酿酒酵母细胞中表达时,其mRNA 5'端先导序列中可能存在影响该基因翻译水平的调控序列。

The plasmid of pEGFP-N1 was preserved in our laboratory.②The rat vibrissa follicles were dissected under a stereomicroscope. The dermal sheath was moved by incubated in dispase. The bulge regions of the hair follicles in anagen phase were carefully cut between the arrector pili muscle and the sebaceous gland, and then incubated with a mixture of trypsin and EDTA. The cell suspension was selected, and cultured in 10% fetal bovine serum DMEM/F12 FAD medium. After 7 days culture, HFSC was obtained by rapid adhering on collagen Ⅳ.

实验方法:大鼠在体视显微镜下分离出含真皮鞘的完整毛囊,dispase消化,将毛囊从真皮鞘中挤出,收集形态完好且处于生长期的毛囊,分别在毛球部上端、皮脂腺下端横切毛囊,取中间部分置于胰酶和EDTA中联合消化,向所得细胞悬液中添加含10%胎牛血清DMEM/F12完全FAD培养基,常规培养7 d后,采用IV型胶原快速贴壁法两次筛选以分离纯化大鼠毛囊干细胞。

In theory, on entry into endosome of tumor cells immunoGrB protein releases C-terminal PE Ⅱ-GrBa into cytosol as a result of auto-cleavage of peptide bond between Arg279 and Gly280. Two kinds of PE translocating peptides covering 253-364 aa and 253-358 aa were compared for their endosome-disruptive function.

一方面,从瞬时表达、可诱导表达和组成性表达三方面研究证明,N端部分PE Ⅱ序列(PE 280-364 aa和280-358 aa)的存在基本不影响GrBa诱导转染细胞死亡的作用。

Overexpression of N1IC, the cell proliferation was modulated, and erythroid maturation of K562 cells was suppressed.

结果显示N1IC的表现并不影响未分化与进行红血球系分化的K562细胞中端粒酵素活性。

Spontaneous discharges of the rostral ventrolateral medulla neurons were extracellularly recorded by multi-barrelled microelectrodes in urethane-anesthetized rats.

实验用多管微电极细胞外记录氨基甲酸乙酯麻醉的SD大鼠延髓头端腹外侧区神经元的活动。

Rodent incisors are known to be continuously growing teeth that are maintained by both the cell-proliferation at the apical end and the attrition of the incisal edge.

啮齿动物的切牙终生不断生长,其高度通过切端磨损及根尖末端的细胞增殖来维持。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。