端细胞

Ovule development began in August, and rectangle megasporocyte began to occur in December, and linear tetrads of megaspores were formed in meiosis. In most occasions, only the chalazal megaspore was functional.

云南红豆杉胚珠从8月开始发生，大孢子母细胞12月开始发生，呈方形，减数分裂后形成4个"一"字形大孢子，在大多数情况下，只有靠合点端的大孢子发育为功能大孢子。

In most multicellular eukaryotes, telomerase is only active in germ cells.

在大多数多细胞真核生物中，端粒只在生殖细胞中有活性。

The difference of both treatments at the concentration of 10nM and 100nM are significant (p.05), Conclusion:The application of ADR and NaBu can inhibit the proliferation of HeLa cells, and the combination of those two drugs is synergistic effect,which is related to the inhibition of telomerase activity and downregulation of hTERT mRNA transcription.

NaBu 和ADR均可抑制HeLa细胞增殖，联合应用具有协同效应，与抑制端粒酶活性、下调hTERT mRNA表达有关。

Methods: WTBZ〗 Telomeras e activity was detected in 38 cases of NPC, 15 cases of PNC adjacent tissues and 19 cases of chronic nasopharyngitis as well as in NHE1 cell lines, two other ca ncer cell lines and three other normal control cell lines by TRAP PCR ELISA and TRAP PCR PAGE respectively.

分别采用TRAP PCR ELISA及TRAP PCR PAGE检测了38例鼻咽癌、15例癌旁组织、19例慢性鼻咽炎和鼻咽癌HNE1细胞株、其它2种癌细胞株及3种正常细胞的端粒酶表达。

Objective:To detect the telomerase activity in esophageal netting cells and explore its clinical application value in the diagnosis of esophageal carcinoma.

目的：检测食管拉网细胞中端粒酶活性，探讨其在食管癌诊断及预测预后的临床应用价值。

The results of SDS-PAGE and differential displays both showed that the composition of cell proteins and the expression of nuclear genes were changed after the loss of plastid.

SDS-PAGE与选择性cDNA 3'端片段的差异显示结果都表明，失去质体之后，细胞的蛋白质组成和细胞核的基因表达发生了改变。

THPL, a newtypesemisynthesis anticancer drug of the kind of anthracene nucleus, adds a pyran ring onthe aminosaccharide of ADR to increase the activity of anticancer and the drugconcentration in target cell obviously, has less demiperiod and side effects.

THP是新一代半合成蒽环类抗肿瘤药物，是在阿酶素的氨基糖4'端加了一个吡喃环，使它抗肿瘤的活性、靶细胞的药物浓度明显提高，半衰期缩短，毒副作用明显减少。

It is well reported that human telomeric DNA sequence [AGGG3] can form a well-defined quadruplex structure with the hydrogen bond between guanine bases in the appearance of K+ and Na+. It was reported that the formation and stability of the structure is meaningful for both gene regulation and apoptosis.

据文献报道，人类染色体端粒中的重复序列[AGGG3]可以在钠、钾离子存在的条件下通过四个G碱基间形成平面环状氢键从而折叠成四链结构G-quadruplex，此结构的形成与稳定对基因调控以及细胞的凋亡有着重要意义。

Currently activities involve (1) Investigation of dye-DNA interaction by using spectroscopic methods to probe the binding sites between chromophore and DNA and to identify various DNA conformational structures, particularly the telomeric DNA;(2) Investigation of the structure-activity correlation of anti-telomerase agents;(3) Design and synthesis new compounds for antitumor agents and fluorescence biomarkers;(4) Monitoring the folding and unfolding of quadruplex structure, tracing the pathway of drug delivery and probing drug-target interaction by using single molecule microscopy and spectroscopy.

目前 的研究重点分别是(1)利用光谱方法探讨探针分子与DNA的交互作用，特别是作用位置与结构变化；(2)研究抗端粒酵素作用分子之结构与生物活性之关系；(3)设计及合成抗肿瘤药剂或萤光生物标记；(4)建立单分子萤光光谱与影像技术，研究 DNA的多变型结构之变化机制，监测药物输送的路径过程及其在细胞中与标的物的作用。

Inhibition of telomerase activity leads the cells to senescence and death.

端粒酶活性的抑制可以导致细胞的衰老和死亡。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。