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PinX1 is an evolutionally conserved nucleolar protein that has been recently demonstrated as a telomerase/ telomere interacting factor in both the humans and the yeasts.

PinX1是近年在人和酵母细胞中发现的一个能与端粒/端粒酶相互作用的保守核仁蛋白。

Following studies had been performed:(1)repetitive WLT and real-time ultrasonography had been performed to 18 HS and 40 FD toassess the reproducibility and influencing factors.(2) correlations of WLT with symptomscore and electrogastrography had been analysed.(3) differences ofWLT between HS and FD had been compared.(4) methophenolane andimmunohistochemistry stain of gastric fundus mucosa biopsy from 40 FD patients hadbeen performed to analyse the correlations of symptom score and WLT with count andactivity of mast cells, 5-HT level, and H.Pylori infectious status.(5) the effect of oralsumatriptan to proximal stomach function in 10 HS and 10 FD had been assessed, so as toestablish the possible regulating mechanism of fundic relaxation, explore the therapeuticpotential and feasibility of sumatriptan on FD.Results:I. Evaluation of WLT and its application in FD management.

我们主要进行以下几个方面的研究:(1)对18名健康人及40名FD患者重复进行水负荷试验并结合B超声对近端胃的实时监测,评价水负荷试验结果的可靠性并分析其影响因素;(2)观察水负荷试验结果与症状积分及体表胃电结果的相关性;(3)比较FD患者和健康成人水负荷试验结果的差别;(4)对40名FD患者胃底粘膜活检组织进行免疫组化染色和甲苯胺蓝染色,观察FD患者的症状及水负荷试验结果与胃底粘膜肥大细胞、5-HT表达情况及H.pylori感染情况的相关性:(5)观察口服舒马曲坦对10名健康人及10名FD患者近端胃功能的影响,并由此推测胃底舒张运动调节的生理机制,探讨口服舒马曲坦治疗FD的可行性。

ER, NGF and ChAT immunoreactive productions were widely presented in diencephalons, mainly in nucleus habenula, nucleus corpus geniculatum lateral, nucleus medialis thalami, nucleus lateral thalami, nucleus paraventricularis, nucleus paratenialis, nucleus rhomboidens, grisea periventricularis hypothalami, nucleus periventricularis hypothalami, nucleus paraventricularis hypoythalami, nucleus ventromedialis hypothalami, anterior region and posterior region hypothalami.

老年大鼠和去卵巢大鼠端脑大部分区域内ER、NGF和ChAT的表达活性及阳性细胞数目均显著下降,而补充17β-雌二醇后得到回升,并基本恢复到正常水平,表明雌激素通过ER对端脑内NGF和ChAT的表达有促进作用,这种作用可能部分地与雌激素对NGF的上调而作用于胆碱能神经元有关,也可能是雌激素通过ER直接调控了ChAT的表达,增强神经信息的传递。

Objective To investigate the effects of different Leptospira strains on phagocytosis of peritoneal macrophages of guinea pigs, and explore the role of innate immune in the pathogenesis of leptospirosis.

目的 通过比较不同毒力钩端螺旋体对豚鼠腹腔巨噬细胞吞噬功能的影响,探讨固有免疫在钩端螺旋体病发病机制中的作用。

ABSTRACT]ObjectiveTo study the expression of telomerase activity in patients with acute myelocytic leukemia and its clinical significance.

摘要]目的研究急性髓细胞白血病的端粒酶活性表达情况,探讨端粒酶活性检测对AML的临床意义。

Objective: To examine changes in gene expression profiling of peripheral blood mononuclear cells in type 2 diabetes patients with distal symmetric polyneuropathy as compared to type 2 diabetes patients without distal symmetric polyneuropathy and to healthy controls.

目的:利用基因芯片技术比较2型糖尿病伴有远端对称性多神经病变的患者、2型糖尿病不伴远端对称性多神经病变的患者以及正常个体外周血单个核细胞基因表达谱的差异。

Methods: We used a 5075 gene cDNA microarray to examine gene expression in peripheral blood mononuclear cells from two type 2 diabetes patients with distal symmetric polyneuropathy, two type 2 diabetes patients without distal symmetric polyneuro...

采用包含5075个功能已知人类基因的cDNA芯片检测2名2型糖尿病并发远端对称性多神经病变患者,2名2型糖尿病不伴远端对称性多神经病变患者以及2名年龄和性别匹配的正常个体外周血单个核细胞基因表达谱。

There are causal relationship between telomere loss and replicative senescence, and telomerase activation and cellular senescence.

文章综述了端粒和端粒酶的结构和功能,及其与细胞衰老的关系,并在此基础之上展望了其应用前景。

The dense retrogradely labelled cell bodies were found in medial magnocellular nucleus of the anterior ne...

在端脑新纹状体前部的大细胞核内侧部、中部的界面核、尾中部的端脑听区、丘脑uvaeformis核及脑桥蓝斑见到大量逆行标记细胞。

The sinus gland is a roughly ellipsoidstructure which is situated dorso-laterally at the transition of the medulla intema andmedulla terminalia.

这些神经分泌细胞发出的轴突汇集成束,形成一条轴路,斜穿过端髓,在端髓与内髓交接处背侧膨大形成窦腺。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。