突触后的

Given this finding, it seems likely that the mechanism underlying response to fluoxetine in patients with premenstrual dysphoric disorder is distinct from that postulated for major depression, which involves postsynaptic downregulation of serotonergic receptors over a period of weeks.

假设这一发现是正确的，则fluoxetine治疗月经前焦虑障碍的机制可能与治疗严重抑郁症不同，后者与突触后血清素激活受体的下调节有关联且维持数周的期间。

GABA is resitent to the toxicity of the excitory amino acids because it can promote the conduct of Cl-, prevent the depolarization of the postsynaptic inhibition effectively and the open of Ca2+-gated channel, reduce the metabolic rate of the ischemic nurons.

GABA可以拮抗兴奋性氨基酸的毒性作用，它主要通过促进氯离子的传导，有效的阻断突触后去极化及电压依赖性Ca2+通道的开放，降低正常灌注/缺血性神经元的代谢率和氧的消耗，从而使神经元易耐受缺血性损伤[9]。

In recent years, ENK-IR neurons in myenteric plexus have been discovered. ENK is one of the important neurotransmitters in ENS. It can reduce the amplitude of cholinergic fEPSP and the release of Ach so as to inhibit contraction of smooth muscles.

近年发现在肠肌间丛神经元中有ENK-IR神经元，脑啡肽是肠神经系统中重要的神经递质之一，可降低胆碱能快速兴奋性突触后电位的幅度，减少乙酰胆碱的释放，抑制平滑肌的收缩。

Results ① Normal morphological structure of brain microvascular endothelial cells and neuroglial cells were injured by 1,2-dichloroethane, which damaged blood-brain barrier.

结果］染毒后的脑微血管内皮细胞呈进行性破坏，随着染毒剂量的加大细胞体积逐渐增大，胞膜模糊，细胞与细胞间、细胞与突触间连接减少，甚至消失；随着染毒时间的延长，在10、30、60min后可以观察到有进行性的细胞膜溶解破坏，胞核模糊，界限不清，突触变短。

ISO prolonged the decay time and increased the total charge transfer of spontaneous inhibitory postsynaptic currents.

ISO 延长自发的抑制性突触后电流的衰减，增加它的总电荷转移。

Chronic blockade of cortical culture activity increased the amplitude of miniature excitatory postsynaptic currents without changing their kinetics.

皮质培养活性的慢性阻抑会增加微兴奋性突触后电位的幅度而不改变它们的动力学。

In the presence of L-isoproterenol (through local infusion into area CA1), the theta-pulse stimulation with the parameter of 10 Hz, 150 pulses/train, 1 train, a frequency weakly modifying synaptic strength, induced a robust LTP, and this effect was blocked when DL-propranolol was co-administered. By contrast, the theta-pulse stimulation with the parameter of 5 Hz, 150 pulses/train, 3 train, a frequency strongly modifying synaptic strength, induced a significantly smaller LTP when DL-propranolol was administered into area CA1. Accordingly, DL-propranolol impaired rat's spatial learning in the water maze when infused into area CA1 20min pretraining.

正常情况下对突触传递效能仅有微小调制作用的10Hz的θ节律刺激（每串150个脉冲，1串），在CA1区局部给予L-异丙肾上腺素后，显著地诱导出LTP，这一效应可被DL-心得安所阻断；相反，正常情况下对突触传递强度有显著调制作用的5Hz的θ节律刺激（每串150个脉冲，3串），在CA1区局部给予DL-心得安后，所诱导出的LTP被显著压抑。

Synaptic inputs activated repetitively within 20 ms before spiking of the tectal neuron become potentiated, whereas subthreshold inputs activated within 20 ms after spiking become depressed.

在四叠体突触尖波20ms前连续被激发的突触输入将造成突触电位化，然而在尖波产生的20ms后的小于临界输入将造成突触抑制。

Synaptic inputs activated repetitively within 20 ms before spiking of the tectal neuron become potentiated, whereas subthreshold inputs activated within 20 ms after spiking become depressed.

在四叠体突触尖波20ms前连续被激发的突触输入将造成突触电位化，然而在尖波产生的20ms后的小於临界输入将造成突触抑制。

Post mortem studies of suicide victims have shown a diffuse reduction in serotonin receptor transporter sites in the ventromedial PFC, and an increase in postsynaptic 5-HT (1A) receptors in localized regions of the PFC.

自杀死亡的尸检研究发现，腹内侧 PFC 的 5-HT 受体转运体位点普遍减少，并且 PFC 的部分区域突触后 5-HT (1A)受体数增加。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！