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However, the advance of intracellular labeling techniques enables us not only to visualize more complete dendritic arbor for qualitative ahalysis, but also to examine the relation between changes in the dendritic arborization and the evoked fast postsynaptic curents in the same neurons during the postnatal development.

但是,细胞内染色技术的进步使我们不仅能观察到更完整的树突分支来用于定性研究,而且也可以在同一神经元上研究在发育过程中树突分支的变化与诱发的快突触后电流(fast postsynaptic currents,fPSCs)之间的关系。

Objective To purify postsynaptic density proteins with better dissolubility.

目的 提取纯度高、易分离溶解的突触后致密物蛋白质。

Neurotrophin-3/neurotrophic factor 3 is the important member of neurotrophin family, which can prevent embryonic and postnatal motoneuron death, maintain neuron survival, promote reparation and regeneration after nervous injury, and regulate synapse activity of neuron.

神经元营养因子-3 (neurotrophin-3, NT-3),是神经营养因子家族的重要成员,具有阻止胚胎期及出生后运动神经元细胞死亡,维持神经元的存活及促进神经损伤后的修复与再生,并参与调节神经元突触活动的作用。

Recordings of the action potential of peroneal nerve trunk showed that the slow conduction fibers (<1m/s) could be activated by the stimulation of SPN with a current intensity of 300μA, but not of DPN.

细胞内记录的资料显示,刺激PF或dPAG也引起几种不同的反应:①有兴奋性突触后电位和动作电位,并有兴奋后超极化现象;②在AP前有超极化现象;③只有EPSP和AP,无明显的兴奋后超极化。

According to the conduction velocity of afferent fibers and stimulus threshold, evoked EPSCs that are mediated by A-like or C-like fibers were distinguished.

以传入纤维的传导速度与刺激阈值为指标,可以区分A 样纤维与C 样纤维兴奋性突触后电流。

After pretreated with antagonist of α 2 noradrenoceptors yohimbine 2 mg·kg -1 ip,the effects of clonidine on kindled rats was then o...

中枢突触后α2 去甲肾上腺素受体参与大鼠杏仁核电刺激点燃和戊四唑化学点燃的调控作用

Autoradiographic studies have demonstrated that adenosine A1 and A2 receptors are expressed in the spinal dorsal horn, both on the post-synaptic SG neurons and the central terminals of the primary afferent neurons.

放射自显影的结果表明A_1和A_2受体都分布在脊髓背角,包括突触后SG神经元和初级传入神经元的中枢突,而A_1受体集中分布于胶状质。

Using sucrose-gap recordings of synaptic transmission across the cockroach cercal nerve-giant fiber synapse,it was observed that the excitatory postsynapic potential was blocked by 0.1 g/L Celangulin Ⅳ after 72 min of medication.

甘露醇间隙法对美洲大蠊(Periplaneta americana中枢神经离体标本兴奋性突触后电位(EPSP的测定表明,质量浓度为0.1 g/L的苦皮藤素Ⅳ在用药后72 min阻断了EPSP。

Long-term modulation of spine density, but not number of primary dendrites, by BDNF was gated by cAMP.

研究表明,BDNF 对突触后树突棘密度的长时程作用也受cAMP 的门控调节,但是BDNF 对神经元一级树突数目的调节并不受cAMP 的调控。

Aim:(1) The purpose of this study is to examine whether protein tyrosine kinase and AMPA receptor in the nucleus tractus solitarius and nucleus ambiguus were involved in the regulation of normoxia and hypoxia respiratory response by microinjection of PTK inhibitor and non-NMDA receptor antagonist;(2) To observe the change of number of phosphotyrosine immunopositive neurons in NTS and NA before and after hypoxia using immunohistochemical methods and whether tyrosine phosphorylation and GluR1 in postsynaptic membrane co-localize in NTS and NA neurons.

目的:(1)观察向家兔脑干孤束核或疑核内微量注射酪氨酸蛋白激酶阻断剂和谷氨酸AMPA受体阻断剂对常氧呼吸和低氧呼吸反应的影响,探讨PTK和AMPA受体在低氧呼吸反应中的作用。(2)观察低氧通气后NTS和NA磷酸化酪氨酸免疫阳性神经元的数量变化;观察磷酸化酪氨酸和AMPA受体亚单位GluR1在突触后膜共存的情况,推测在低氧呼吸反应中AMPA受体和PTK信号转导途径的关系。

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