突触前的

However, we observed distinct abnormalities within presynaptic terminals of spinal MNs at the neuromuscular junction, as well as profound denervation.

无论如何，我们观察到神经肌肉接头处的脊髓运动神经元突触前末梢的明显的异常，还有显著的去神经支配。

SP can affect the function of DRG neurons by activing the non-selective cation channels combining with its selective NK1 receptor. ATP depolarize DRG neurons and make some sodium channels closed so that the amplitude of action potentials and Vmax decreased which result in decreaced releasing of neurotrasmitters from DRG neurons, the way is same like GABA-induced presynaptic inhibition by activing the non-selective cation channels possibly combining with P2X2/3-receptor.

SP可能通过开放非选择性阳离子通道从而影响DRG神经元膜的兴奋性；ATP通过与P2X2/3-R结合开放非选择性阳离子通道，使得A类神经元膜预先去极化，引起膜钠通道部分关闭，动作电位幅值降低，斜率Vmax减小，使神经末梢递质释放减少，其作用与GABA介导的突触前抑制类似。

Agkistrodotoxin, a presynaptic neurotoxin and one of the two neurotoxins from the snake venom of Agkistrodon halys Pallas, has been further purified by DEAF -cellulose and CM-Sephadex column chromatography and vertical slab polyacrylamide gel electrophoresis.

本文在前文的基础上，改进了蝮蛇神经毒素的分离方法，纯化了蝮蛇毒中的两个神经毒素之一，突触前神经毒素Agkistrodotoxin，并对其生化特性进行了分析。

Complete resolution of detrusor overactivity was observed in 44% of BTX-A patients at 4 weeks, though this dropped to 25% by 24 weeks.

重链结构BTX对运动神经末梢突触前膜的结合及内化有关；轻链结构与BTX抑制神经递质的释放有关。

Presynaptic inhibition acts to suppress sensory signals from skin and muscle receptors and to decrease the amount of glutamate

突触前抑制的机制是抑制来自于皮肤和肌肉的感觉信号、并降低谷氨酸的释放。

This enzyme catabolizes norepinephrine and serotonin in their respective presynaptic neurons, and such inhibition could be expected to increase the availability of neurotransmitters.

此酶分解代谢去甲肾上腺素和 5-羟色胺在他们各自的突触前神经元。这样的抑制作用可能预期增加神经递质的利用率。

Presynaptically bound opiates may inhibit Ca2+ channels, activate inwardly directed K+ pumps, or inhibit the production of adenyl cyclase.

突触前结合阿片制剂可以抑制钙通道，激火内部的钾泵，或抑制腺苷酸环化酶的生成。

It is important that precise timing between pre- and postsynaptic activities may be used to encode information in neural networks.

突触前、后细胞的活性配合时间对於神经回路之中讯息的储存是相当重要的。

METHODS: The maximum number of platelet binding sites and their affinity for [3H]-rauwolscine, a selectie alpha 2-AR antagonist, were measured in unmedicated and medicated major depressed patients and in normal olunteers.

背景：曾认为抑郁症可以伴随中枢α2肾上腺素受体密度的降低，继发突触前儿茶酚胺神经元负性反馈的损害，导致刺激后去甲肾上腺素输出和释放去抑制功能的减弱。

Chronic psychological stress can increase GC in Plasma and brain by HPAA. There are plentiful GR on Hippocam--pal cell membranes. It promote presynapitic membrane assoiling EAAs when GC combines with GR.

心理应激通过 HPAA 使血浆及脑组织中的 GC 升高，海马神经元细胞膜上存在丰富的 GR ， GC 与 GR 结合后，可促进神经元突触前膜释放兴奋性氨基酸。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。