突触

Objective To count the number of ribbon synapses in cochlear inner hair cell using three-dimensional reconstruction model.

目的利用三维建模的方法对耳蜗内毛细胞带状突触进行计数分析，解决由于内毛细胞带状突触数量少、位置深在造成的计数困难，为内毛细胞带状突触的可塑性研究提供有效可靠的计数方法。

Nerve impulse is conducted from one neuron to another neuron. The chernical synapse is composed of three

突触前份、突触后份和突触间隙组成，传导神经冲动的化学物质称为神经递质。

The results are indicated that only the strength of gap junction is large enough, can the abnormal oscillation propagate to synchronize the other neurons around and the process is chaotic and complex;the nonlinear and complexity of the oscillations with strong strength of gap junction are larger than that of oscillation with weak strength of gap junction.

结果表明：只有电突触耦合达到一定强度时，异常振荡才能传导并引起神经元的同步振荡；传导活动是混沌和复杂的；在突触耦合强度较强时的神经元活动的非线性和复杂性要强于其在突触强度较弱时的。

Three results are received:(1) The population of neurons can synchronize when the strength of gap junction is large enough and the process is chaotic and complex;(2) The nonlinear and complexity of the seriously disorder oscillation are larger than that of slightly disorder oscillation in a 2-D network;(3) The nonlinear and complexity of the oscillations with strong strength of gap junction are larger than that of that with weak strength of gap junction.

结果表明：电突触达到一定强度时神经元群才能同步振荡，这种活动是混沌和复杂的；同一网络中异常节律较严重的神经元活动的非线性和复杂性要强于异常节律较轻微的神经元；突触耦合强度较强时的神经元活动的非线性和复杂性要强于其在突触耦合强度较弱时的。

A major challenge in studying the synapse is how to tell what observed effects are due to presynaptic factors and which to postsynaptic ones.

研究突触最大的困难在於如何区辨所观察到的反应是来自突触前或突触后因子所导致。

Moreover, we found that presynaptic but not postsynaptic inactivation of presenilins alters short-term plasticity and synaptic facilitation.

并且我们还发现突触前而非突触后早衰蛋白失活将改变短时突触可塑性及易化。

In the progress that presynaptic neuron was excited,which caused postsynaptic potential changing by the release of neurotransmitters,and then electrical signal was transferred,the function and form of synapses could change.

在突触前神经元兴奋，通过神经递质的释放，引起突触后电位的变化，从而完成电信号的传递过程中，突触本身的功能和形态都可能发生改变。

D. Excitatory postsynaptic currents evoked by different types of primary afferent fiber were distinguished with two measurements: the conduction velocity of afferent fibers and stimulus threshold.

d。应用纤维传导速度与引起突触后电流的刺激阈值二个指标，可区分不同类型突触前纤维介导引起的兴奋性突触后电流。

Pentylenetetrazol is a central nervous system drug that induce chronic and acute epilepsy model to study epileptogenous mechanism .Kindling is a natural epileptogenous phenomenon.

我们前期研究工作发现：应用电镜、Timm染色等从形态结构方面已证实在点燃前神经元发生了可塑性改变包括苔藓纤维芽生，新突触形成(突触密度增大或数量增多)与突触重排等，但这些只是一个初步探索，仍不能够说明问题的全部，如其分子生物学基础、神经元凋亡情况等尚不清楚，需进一步研究探讨。

Based on above results, we conclude that the synaptic depression of thalamic input to the cortex contributes to rapid adaptation in cortical neuron, and both the thalamocortical and intracortical synaptic transmission could then enhance the degree of adaptation.

基于以上结果，我们认为，持续刺激引起的丘脑—皮层突触的抑制对皮层神经元的快速适应有贡献，而丘脑—皮层突触以及皮层—皮层突触的放大机制都可以将这一特性进一步增强。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！