突触

AIM: To observe the effect of total ginsenoside on synaptic transmission in the dentate gyrus.

目的：研究人参总皂苷对麻醉大鼠海马齿状回突触传递活动的影响。

Our observation indicates that morphine may selectively depolarize most C DRG cells, which might be mediated and enhanced by adenosine.

腺苷可能介导和加强阿片类在脊髓的突触前抑制作用。

Likewise, brief spontaneous increases in [Ca2+]i, sensitive to BMI and TTX, are observed at the same ages, suggesting that endogenous synaptic GABAA receptor activation can depolarize cells and activate VGCCs.

同样，短暂的[Ca2+]i自然上升对BMI和TTX敏感，可以在相同年龄上观察到，这显示出内圣突触GABBA受体活化可以为细胞去极化，并活化VGCCs。

They express widely inperipheral and central nerve system and participate in many important physiological andpathological processes,such as learning and memroy,synaptic plasticity,cerebral ischemiaand pain.Activation of ASICs by protons can depolarize the neurons and generate action potentials.

它广泛分布于中枢及外周神经系统的神经元，参与了很多重要的生理过程和病理反应，与学习记忆、突触可塑性、脑缺血、疼痛等关系密切。H~+激活ASICs可使神经元去极化，产生动作电位，参与了组织酸化如缺血、炎症、肿瘤、癫痫等时痛觉的感受。

SP can affect the function of DRG neurons by activing the non-selective cation channels combining with its selective NK1 receptor. ATP depolarize DRG neurons and make some sodium channels closed so that the amplitude of action potentials and Vmax decreased which result in decreaced releasing of neurotrasmitters from DRG neurons, the way is same like GABA-induced presynaptic inhibition by activing the non-selective cation channels possibly combining with P2X2/3-receptor.

SP可能通过开放非选择性阳离子通道从而影响DRG神经元膜的兴奋性；ATP通过与P2X2/3-R结合开放非选择性阳离子通道，使得A类神经元膜预先去极化，引起膜钠通道部分关闭，动作电位幅值降低，斜率Vmax减小，使神经末梢递质释放减少，其作用与GABA介导的突触前抑制类似。

Indeed,〓receptor desensitization is fast enough to control the time course of GABA-evoked synaptic events.

实际上，〓受体的脱敏速度已足以控制GABA诱发的突触事件。

But the compulsion to embroider, to dissemble and to dissimulate is now so entrenched in the synapses of the Clinton brain that it came to her as naturally as the truth would to a slow-witted innocent.

但强制刺绣，以dissemble和分化，现在如此根深蒂固，在突触的克林顿脑部，它来到她顺其自然真相会以缓慢的机智无辜的。

Objective To purify postsynaptic density proteins with better dissolubility.

目的 提取纯度高、易分离溶解的突触后致密物蛋白质。

Dr Tononi believes that the function of these slow waves is to "downscale" synapses, reducing their size, chemical activity and electrical activity—and thus the strength with which they connect their nerve cells together—all over the brain.

托诺尼博士认为这些慢波的功用是削弱突触，减小它们的尺寸、化学活动和电活动，从而在整个大脑范围内减弱神经细胞间的联系。

This might be one of the mechanisms that underlie presynaptic inhibition in DRG.

这可能是腺苷参与镇痛的突触前抑制机制之一。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！