突触

Using visual patch-clamp method synaptic transmission can be accurately assessed by measuring postsynaptic currents of the dorsal horn neurons.

用可视膜片钳方法可以准确测量脊髓背角神经元的突触后电流，从而研究初级传入突触的传递过程。

Whole-cell recordings were performed to record miniature excited postsynaptic currents after neurons were cultured for 1 week and 2 weeks.

培养到1周和2周时，采用膜片钳全细胞模式记录神经元突触内自发的微小兴奋性突触后电流。

RESULTS: Lidocaine inhibited both EPSP and the response foracetylcholine of the postsynaptic neuron.

结果：利多卡因同时抑制了兴奋性突触后电位和突触后神经元对乙酰胆碱的反应。

The immediate effects of this pharmacologic action are to increase the availability of norepinephrine and serotonin in the synapse and to increase stimulation of the postsynaptic neuron.

药理学活性的瞬即效应是为了提高突触对去甲肾上腺素和 5-羟色胺的利用率，也为了增值突触后神经元的兴奋。

In the presence of L-isoproterenol (through local infusion into area CA1), the theta-pulse stimulation with the parameter of 10 Hz, 150 pulses/train, 1 train, a frequency weakly modifying synaptic strength, induced a robust LTP, and this effect was blocked when DL-propranolol was co-administered. By contrast, the theta-pulse stimulation with the parameter of 5 Hz, 150 pulses/train, 3 train, a frequency strongly modifying synaptic strength, induced a significantly smaller LTP when DL-propranolol was administered into area CA1. Accordingly, DL-propranolol impaired rat's spatial learning in the water maze when infused into area CA1 20min pretraining.

正常情况下对突触传递效能仅有微小调制作用的10Hz的θ节律刺激（每串150个脉冲，1串），在CA1区局部给予L-异丙肾上腺素后，显著地诱导出LTP，这一效应可被DL-心得安所阻断；相反，正常情况下对突触传递强度有显著调制作用的5Hz的θ节律刺激（每串150个脉冲，3串），在CA1区局部给予DL-心得安后，所诱导出的LTP被显著压抑。

Synaptophysin is one of the important markers of synaptic rebuilding.

突触素是突触重建的重要标记之一。

They play a pivotal role in the regulation of synaptic transmission and synaptic plasticity in the central nervous system.

NMDA受体是包含谷氨酸和甘氨酸结合位点的配体门控性离子通道，在中枢神经系统的突触传递和突触可塑性调节中起着重要的作用。

It required spiking of postsynaptic tectal cells as well as activation of NMDA receptors, and effectively occluded long-term potentiation of retinotectal synapses induced by direct electrical stimulation of retinal ganglion cells.

这需要突触后顶盖细胞的脉冲和NMDA受体活化，并有效闭塞连接视网膜和中脑顶盖神经纤维的突触长期的增强，这是由视网膜活动中心细胞的直接电激诱发的。

Within paired-pulse stimulation of any inter-stimulus interval used in our experiments, the field potentials induced in thalamocortical visual pathway of adult rats were depressed rigorously.

在实验采用的所有刺激间隔下，双脉冲刺激都能明显抑制正常成年大鼠外侧膝状体到初级视皮层的突触传递，不过突触传递的抑制程度并不完全是随着刺激间隔的增加而减小。

To understand the basic properties, underlying mechanisms and functions of the short-term synaptic plasticity of thalamocortical visual pathway, we combined in vivo field potential recording, focal drug application technique and neuron models, to explore the short-tem synaptic plasticity of rat major thalamocortical visual pathway (from lateral geniculate nucleus to primary visual cortex) and extrageniculate pathway (from lateral posterior nucleus to primary visual cortex), as well as the role of short-term depression in the neuronal correlated firing detection.

我们结合在位场电位记录、局部加药和神经模型等方法，对不同刺激模式下大鼠丘脑皮层主要视觉通路（外侧膝状体到初级视皮层）和非主要视觉通路（膝体外通路：丘脑侧后核到初级视皮层）的短时程突触可塑性，以及短时程抑制作用对神经元同步活动检测的作用做了研究，试图了解视觉丘脑皮层突触传递短时程可塑性的基本特性、神经机制和功能。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！