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Results: This group included 31 TCCF patients with the characteristics: the incidence rate of this disease for male is higher than that for female; the average age is 38.2 year-old, the male average age is lower than that of female. The common clinical symptoms are pulsatile intracranial bruit, pulsating exophthalmos and congested and edema conjunctiva, which usually appeared in 7 days after the trauma. These symptoms even appeared two months after the trauma in exceptional patients. Among the 31 patients, 13 patients didn't get timely diagnosis and treatment when they had presented typical symptoms.

临床症状主要表现为搏动性突眼、颅内杂音和结膜充血水肿,症状出现时间主要在外伤后7天内(25/31),个别患者在伤后近两个月出现症状。31例患者中,13例患者出现首发症状后没有得到及时诊断和治疗。31例患者均行DSA确诊,其中29例患者采用球囊栓塞瘘口,1例行弹簧圈填塞海绵窦,1例行覆膜支架封闭瘘口。

Gene mutations were detected in 25 patients and a 18-year-old girl among 16 families. Trinucleotide repeats of CAG were 73~79. The fragments of abnormal alleles were 380~402bp, and all patients were heterozygous. The copy numbers of normal alleles were 18~40, fragments from 202~270bp. SCV reduction was much obvious compared to MCV, MCV and SCV in lower limb ?ere much more slow than that in upper's. BAEP, VEP were also delayed in latency. The anticipation in parental sex bias were much more obvioius than that in matental's. Cerebellar ataxia was most severe, the next were dysarthria and bulging eyes. Amytrophy was seen only in bed ridden patients. Cerebellar atrophy was more severe than brain stem, cord atrophy was n't observed in all MJD.

结果检出10个家系25例病人及1例症状前18岁女孩有MJD基因突变,CAG三核苷酸重复73~79次,异常等位基因片段长380~402bp,均为杂合子;正常人CAG三核苷酸重复18~40次,等位片段长200~270bp,电生理发现MJD的SCV减慢比MCV明显,而下肢的MCV、SCV又较上肢明显,BAEP、VEP均有不同程度的潜伏期延长或波的异常;MJD的父亲遗传早于母亲,进展也较块,临床以小脑性共济失调为突出症状,其次为构音障碍、突眼等,肌肉萎缩仅见于晚期病人;MRI示小脑萎缩较明显,脑干萎缩并不严重,未见明显的颈髓萎缩。

In most cases exophthalmos affects both eyes.

在大多数情况下,突眼既影响眼睛是雪亮的。

Objective: To explore the clinical efficacy and case analysis of Tripterygium Wilfordii united Tapazole Prednisone in the treatment of hyperthyroidism exophthalmos.

目的:探讨采用雷公藤多苷联合他巴唑强的松治疗甲亢突眼临床疗效及病例分析。

Objective:To investigate the relationship between serum antibodies to glutamic acid decarboxylase and Graves' disease.

目的:研究谷氨酸脱羧酶抗体与Graves'病病程及浸润性突眼的关系。

He presented the typical clinical pictures of orbital apex syndrome, including right eye ophthalmoplegia, proptosis, ptosis, fixed and dilated pupil, hypesthesia over his right forehead, and visual impairment of his right eye.

在临床上表现出典型的眶尖症候群症状,包括右侧眼球转动障碍、突眼、眼睑下垂、固定且放大的瞳孔、右前额区感觉异常,以及右侧视觉异常。

High iodide intake may aggravate patient's clinical symptoms such as thyrocele and ophthalmopathy, but there is no relation between level of UI and thyroid function .Improper iodine supplement to AITD patients may strengthen the immune function disorder .The abnormal increase of cytokine IL-1? and expression of CD80、 HLA-DR on PBMC may involve in the mechanism.

高碘可能加重了AITD突眼、甲状腺肿大等症状,但与甲状腺功能状态没有明显关系;本研究还提示对AITD不适当的补碘可能会导致甲状腺局部乃至全身的免疫功能失调,IL-1β等细胞因子和PBMC表达的HLA-DR、CD80异常与高碘导致的免疫紊乱可能有一定关系,值得进一步探讨。

Any of various fishes,such as the walleye,similar or related to the pickerel.

小梭鱼科类似狗鱼的鱼,或与狗鱼有亲缘关系的鱼,如突眼

Objective To investigate the effect of steroids on proptosis and Th1/Th2 cytokines in Graves ophthalmopathy.

目的 探讨糖皮质激素对Graves眼病突眼的疗效以及对Th1/Th2细胞因子的影响。

This Mets-analysis demonstrates that SSAs are effective in treatment of Graves ophthalmopathy and in reduction of proptosis, and it is equally effctive as glucocorticoid.

生长抑素类似物治疗Graves眼病有效,能减轻突眼的程度,其疗效与糖皮质激素的作用相当。

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