突变的

To investigate the disorder of Wnt signal transduction pathway in tumorigenesis, we studied the adenomatous polyposis coli gene and β-catenin gene mutations in desmoid-type fibromatosis.

本研究分析了韧带样型纤维瘤病中APC和β-catenin基因突变，探讨Wnt通路中APC/β-catenin基因异常在肿瘤发生中的作用。

Compared to the wild type, the mutants' resistant capacity to Cu~(2+) declined and indicates that the Copper-transporting P-type ATPase gene plays an important role in resistance to heavy metal ion such as Cu~(2+) in filaceous fungi Penicillium janthinillum GXCR

对突变体进行抗铜水平检测发现抗Cu~(2+)能力与野生型对照有下降，表明铜转运P型ATP酶基因在丝状真菌微紫青霉菌Penicillium janthinillum GXCR的抗铜能力上起一定作用。

At first, from about 2500 rice mutant lines 481 T-DNA flanking sequeces were isolated.

首先，从大约2500株水稻突变体中，我们分离了481个T-DNA的侧翼序列。

However, follicular variant of papillary carcinoma has a much lower frequency of mutation.

但是，滤泡型乳头状癌的突变率却罕见。

Nutrient cells were obtained from these pigment mutants by enzymatic method and conchocelis were got by parthenogenesis. When the conchocelis were mature and conchospores were released, they were cultured singly and picked up as F1 gametophytic thallus.

通过酶法分离突变体的营养细胞，单性生殖获得丝状体；分别使丝状体成熟并放散壳孢子，然后单株培养和筛选获得褐黄、翠绿和褐绿色子代叶状体。

60Co-γray was a useful mutagen in induced mutation breeding .After treated with 60Co-γray ,free-living conchocelis of wild Porphyra haitanensis were induced and represented in offsprings. Purple mutant and excellent practical characters strains were selected from a lot of gametophytic blades. Single cell clone and enzymolysis were used to propagate fast in pure strains of induced mutations.

坛紫菜野生丝状体经一定剂量60Co-γ射线辐照后，子代叶状体发生了变异，经大量培养后筛选出紫色突变体（3号Ⅰ）和经济性状优良的个体（7号Ⅰ和7号Ⅱ），通过体细胞酶解和单克隆技术快速获得诱变选育纯系，并对其主要经济性状进行了研究。

The gene of human proinsulin mutant (A21Asn→Gly,B17Leu→Ile,B31Arg,B32Arg,GIRR ) was synthesized and recombinated to the fusion protein expression vector pTXB1 and expressed in E.coli BL21(DE3) with high protein level.

构建人胰岛素原突变体GIRR（A21Asn→Gly，B17Leu→Ile，B31Arg，B32Arg）基因的原核融合表达载体并进行表达和纯化，进一步对其性质进行研究。

The parents of patient A, mother of patient B and her son were all heterozygous.

我们所鉴定到两个新的FV突变基因，经文献检索未见类似报道。

The presence of heterozygous of the variant did not alter the bioactivity of LH.

本研究未发现突变杂合子改变了LH的生物学功能。

No homozygous deletions were found in the MTS1 gene,while point mutations were found in 2 of 18 bladder cancers.

研究表明在多种肿瘤细胞中存在着MTS1基因的纯合缺失和点突变［3～7］。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。