突变的

In the 9September 1999issue of Nature,molecular geneticist Enrico Coen and colleagues at the John Innes Centre inNorwich,U.K.,reported that a mutant version of the toadflax plant--which results in flowers with radial rather thanbilateral symmetry--is due to an epimutation.

在1999年9月9日的《自然》杂志上，英国Norwich，John Innes 中心的分子遗传学家Coen和同事报道了云兰属植物Linaria vulgaris的一个突变体特征。这一特异突变导致它的花从双面对称变为辐射状。

To clone new disease gene of CMT, many myelin and myelin-related gene had been analysised by homologue searching. Quaking mouse, one of the mutation mouse with the clinic feature similar to Trembler mouse (the gene mutation mouse of PMP22) with the characterization of demylination in both the central and the peripheral nervous system, its disease gene had just been cloned accession No.

为进一步克隆新的CMT致病基因，在分析出CMT已克隆的基因均为与髓鞘有关的基因后，通过筛选有关髓鞘基因，我们发现，quaking基因突变小鼠因髓鞘形成障碍而出现震颤，其中枢和周围神经均有脱髓鞘，类似于PMP22基因突变鼠"Trembler"的临床表现。

Many of the changes caused by these mutations will be unnoticeable; however, by chance a mutation may occur in a gene that produces a phenotypic change.

很多的变化所造成的，这些突变会unnoticeable ，但是，一个偶然的机会， A突变可能发生在一个基因所产生的表型变化。

"My colleague James Waldron and I began screening different cell lines for mutations and trying to match these mutations up with proteins that suppress the immune system," Parsa said.

"我和我的同事James Waldron开始就突变寻找不同的细胞株，试图找到与这些突变相匹配的抑制免疫系统的蛋白质" Parsa说。

The results suggest that all of the oxygen consumption rates and ammonion exretion rates of juvinile turbots of the 6 groups have a slowly increasing trend, and the bigger extent salinity changed, the more distinct trend appeared.

结果表明：盐度改变后，各突变组大菱鲆幼鱼的耗氧率和排氨率都呈现出不同程度的逐渐升高的趋势，随着盐度突变范围的增大变化趋势更为明显。

The analysis of the mutants of amrA and amkA showed that the production of rifamycin SV had decreased about 10%-20%.

用双交换法在地中海拟无枝菌酸菌U32染色体上插入阿泊拉霉素抗性基因，成功地构建了了amrA，amkA和amrB基因的突变株，其中amrA，amkA基因突变株的菌丝形态与野生型U32之间有较明显的差别，在菌丝的末端形成卷曲或弯曲。

A mutant CopR, which lacks the N-terminal signal receiver domain and is constitutively active, was found to have an attenuating effect on bacterial virulence when expressed in TSS.

本实验还筛选到一个CopR的突变体C104，该突变体因缺失N端的信号接受域而成为一个具有组成性活性的调控蛋白，C104在TSS中表达时导致菌株的毒力降低。

Yeast also is an important research material and provides a detectable experimental system in genetics and molecular biology. The functional complementation assay of homeotic gene re-expression in yeast mutant has become a screen tool in mechanism research of drug.

第三章spm1、pmp1和mid2基因在相应粟酒裂殖酵母突变体中的再表达利用酵母突变体及其同源基因再表达的功能互补实验，是目前遗传学和分子生物学研究的一种重要实验方法，并使酵母成为筛查药物作用机制的工具。

Most mutations were homozygous and affected c-Cbl; mutations in Cbl-b were also found in patients with similar clinical features.

大多数突变为同型结合和受累的c-Cbl；在具有相似的临床特征的患者中也发现了Cbl-b的突变。

Results (1)Multiple copies of pMCLacI/Neo plasmid DNA were intactly integrated in the genomic DNAs of the cell clone.(2) One of lac Ⅰ target genes in the integrated plasmid could be transcribed in the NIH3T3 cells while the other could not.

因此，在这些突变婴儿检测系统中，通过一些不表达的中性靶基因所婴儿检测到的突变规律肿瘤是否代表体内一些重要的功能基因的真实情况，目前尚不清楚［1-3］。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。