突变的

The use of retrovirus-mediated insertional mutagenesis in zebrafish has led to the mutation and rapid identification of hundreds of genes required for embryonic development and cell growth.

运用反转录病毒介导的插入突变技术，在脊椎动物斑马鱼中已经获得了许多影响胚胎发育和细胞生长过程的突变体，并找到了对应的基因。

To study the function of this ORF, we constructed Tn5gusA5 insertional and integrational mutants in the corresponding gene of wild type strain 8004 and analyzed the phenotypes of the mutants.

为了研究该σ因子在Xcc中的作用，我们构建了该基因的Tn5gusA5的插入突变体和pK18mob定点整合突变体并进行了表型分析。

The mutation of p53 was significant in patients with esophageal carcinoma , it takes place in the early stage and was irrelated to thesexual distinction , the location of disease , the biological level , the depth of invasion and lymph node metastasis.

1、在食管癌组织中，存在明显的p53突变，突变率与患者的性别、病变部位、肿瘤分化程度、浸润深度、有无淋巴结转移均无关，是恶性肿瘤的早期事件。

The mutation rates were 30% and 25% in LBC and FM,respectively. It was \ mation of infinite life span human cell strain by transfection with v-Ki-ras.Oncogene,1990;5:1415. 6\ Yang D,Louden C,Reinhold DS,et al.Malignant transformation...

这一结果表明p53基因突变在大肠癌中的普遍存在，并在大肠癌的发生过程中起着重要作用；而家族成员中发现p53基因突变将可为癌症的癌前监控和预防提供重要佐证。

The results showed that there was a mutation of A → G in BMPR-IB gene in Cele sheep,Duolang sheep,Chinese Merino monotocous line and Hu sheep,which were the same as in Booroola Merino ewes.

结果表明，在策勒羊、多浪羊、中国美利奴羊多胎类型和湖羊等品种中都存在和Booroola Merino羊相同的BMPR-IB基因的突变(A746G)，而在中国美利奴羊中没有发现相应的突变。

The experiment shows that human pancreatic cancer cell line Patu 8988 has GGT→GTT mutation at codon 12. The method of PCR-SSP is rapid, convenient, economical and high specific for detecting K-ras gene point mutation. The goal in the long term is to develop a simple and useful clinical procedure for early diagnosis and differential diagnosis of pancreatic cancer.

明确了人胰腺癌细胞株Patu 8988 K-ras基因第12位密码子点突变方式，为胰腺癌的下一步基因治疗研究打下了坚实的基础；PCR-SSP方法检测K-ras基因点突变简便、快速、经济且特异性高，有望在临床上成为早期诊断和鉴别诊断胰腺癌的实用检测方法。

When asked how quickly he thought the current virus would mutate, he called that the "million-dollar question." Dr. Sandrock noted that "it takes a while for the virus to mutate and spread, but once it's up and going, we'll see a surge in the numbers and deaths."

当被问道他认为现在的病毒有多快发生突变时，他表示这是个价值数百万的问题，Sandrock医师指出，病毒突变和扩散需要时间，但一旦它发生了，我们将会看到激增的病例与死亡。

Results:(1) The conchosporangia of brown yellow mutant was smaller and mature time was 15 days later than the parents. Thallus grew slowly in early stage, but average daily growth rate reached (7.50±1.18) cm after blade length was over 60 cm.(2)The emerald conchocelis were easy to mature and had special developmental mode that the spherulocytes can directly develop into sporangial branchlets and conchosporangia without thick conchocelis stage. Emerald blades were low in RPE with just (6.4710±0.0184) mg/g dry mass. The thallus grew quickly, average daily growth rate reached (11.95±2.33) cm after blade length was over 60 cm.(3) The conchocelis filaments of breen mutant were thin and short. Thallus grew slowly and had low contents of three phycobiliprotenin and chlorophyl.

实验进行50d。结果：(1)褐黄色突变体藻蓝蛋白和别藻蓝蛋白含量低；孢子囊枝的细胞较小，且大量形成时间比亲本晚15d；幼苗培养初期日平均生长量仅为(1.22±0.28)cm，当叶片长到60cm左右时生长优势逐步凸显，日平均生长量可达(7.50±1.18)cm；(2)翠绿色丝状体容易成熟，发育方式特殊，营养藻丝不经过藻丝加粗阶段，直接由球形细胞发育成孢子囊枝和壳孢子囊；翠绿色叶状体藻红蛋白含量低，仅有(5.5130±1.0496)mg/g；叶状体生长快速，60cm长的藻体日平均生长量高达(11.95±2.33)cm；(3)褐绿色突变体藻蓝蛋白、别藻蓝蛋白和藻红蛋白这3种色素蛋白和叶绿素的含量均较低；藻丝细胞短且细，叶状体生长速度较慢。

In this study, we determined that the antimutagenic properties of various tea extracts including green, oolong, pu-erh tea, and black tea and six polyphenols include rutin, quercetin, apigenin, gallic acid, umbelliferone, and tannic acid were examined by Ames test which is a widely applied short-term bacterial assay for detecting DNA damage effect of mutagen.

在本篇研究中，我们探讨利用Ames test的方法筛检不同品种茶类包括绿茶、乌龙茶、普洱茶、红茶和数种常见的多酚类化合物包括单宁酸tannic acid、gallic acid、rutin、umbelliferone、apigenin、quercetin对於抑制PhIP（2-amino-1-methyl-6-phenylimidazo(4，5-b)pyridine）和 2-AAF（2-Acetylaminofluorene）两种致突变剂的抗突变作用。

John Winkelman, medical director of the Sleep Health Center at Brigham and Women's Hospital in Boston.Winkelman's editorial also pointed out that two other soon-to-be-published studies confirmed the link to this gene variant and RLS in a different population, and found two other genetic variants linked to RLS.

John Winkelman（波士顿布理格姆妇女医院睡眠健康中心医学主任）博士指出&腿多动综合症具有较强的家族遗传背景& Winkelman社论同时指出，另外两篇即将发表的研究论文证实了在不同人群中这个基因突变与RLS有关联，以及发现另外两个与RLS相关的遗传突变。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。