突变的

It is also necessary in the growth, alignment and septation of the cardiac out flow tract. TBX1 is regulated by a series of upstream genes, and it also regulates a series of downstream genes.

最近通过突变分析发现在小鼠和斑马鱼体内的TBX1纯合子无义突变可导致类似22q11·2DS的咽弓和其相关结构缺陷为特征的表型。

These suppressors can restore septation and conidiation in the absence of the SEPH protein. By the cross and backcross, the temperature sensitive strain Sin110 was obtained and the bypass of SIN pathway was identified.

通过对突变株进行杂交和回交等遗传学分析，排除了sepH回复突变菌株，获得了能使sepH胞质分裂恢复正常的温度敏感菌株Sin110，证实了SIN途径具有对应反向的旁路途径的存在。

The neighbouring Streamside Colony wipes out the Trailheaders, then itself falls victim to a "supercolony", comprising millions of workers and thousands of queens, which rose to power thanks to a single-gene mutation that weakens their sensitivity to queen-odours, and thus permits them to tolerate multiple simultaneous queens.

邻近的"河边蚁群"彻底摧毁了"道口蚁群"，后来，"河边蚁群"自身又成了"超级蚁群"的刀下鬼。"超级蚁群"由数百万工蚁和数千只母蚁王组成，该群得以成长为超级群，缘于一次单基因突变，该突变削弱了蚁群对母蚁王气味的敏感度，从而，使得蚁群可以接受数个母蚁王同时存在。

Thus, it is suggested that enlarging the mutant library via tissue culture should be feasible in rice.

因此，利用组织培养的方法获得更多的突变体来构建突变体库是可行的。

We reviewed the update on germ-line epimutations of TSGs including the possible mechanisms underlying germ-line epimutations, the possibility of transgenerational inheritance, and their impact on our understanding of human disease.

本文着重对近年来抑癌基因胚系表观突变研究进展作一综述，探讨胚系表观突变可能的产生机制和代间遗传的可能性，并展望其给人类疾病病因研究所带来的深远影响。

Enterobacter aerogenes was irradiated by He-Ne laser to optimize the laser mutagenesis condition, and to test the heredity, aciduric and hydrogen-producing potential of the mutant. An aciduric mutant with steady hydrogen-producing capability, which was able to grow at acidic pH of 3.0, was obtained. Its capability of hydrogen production was measured in the batch culture experiment.

闻建平，陈宇，刘铭辉(天津大学化工学院生物工程系，天津300072)摘要：运用He—Ne激光辐照产气肠杆菌，对激光诱变参数进行优化，考察了突变株的遗传稳定性、耐酸性和产氢特性结果筛选到一株遗传性状稳定的高产氢突变株，具有良好的耐酸性，在pH值3.0 时仍能生长。

Two kinds of highperformance expressions of eukaryotic system of human mutant CD59 cDNA were successfully established, which makes further study of mutant CD59 glycation and anticomplement activity possible, and thus elucidate the mechanism of blood vessel proliferation in diabetes.

成功建立了两种高效表达人CD59突变体的真核表达系统，能够进一步研究人CD59的突变体糖基化及抗补体活性，为阐明糖尿病血管增殖性病变的发病机制奠定了基础。

Studies on the mutant breeding of high-yield gibberellins strain The protoplast of Gibberella fujikuroi m978 were treated by mutation breeding forhigh-yield gibberellins, LiCl mutation was better than DES mutation or UV irradiation ifsingle mutation, but any single mutation was worse than compound mutation by whichthe mutants were more overproducting and genetically stable.

采用传统诱变育种，筛选高产菌株在原生质体条件下，对赤霉素产生菌m978的原生质体进行菌种选育；使用单因子诱变方法，LiCl处理的效果优于DES诱变和UV诱变；复合诱变比单因子诱变更容易得到高产突变株，且获得的高产突变株稳定性更优。

Approximately 1% of mutations occur de novo ; thus, 1% of probands have only one parent who is heterozygous.

约1%的突变是新生突变；因此，1%的先证者只有一个杂合子的父母。

Direct sequence analysis of exon 17 showed that homozygous and heterozygous nonsense mutations were silent polymorphism at position 1058.

结果 发现11例外显子17和1例外显子20的异常电泳条带，外显子17的突变经顺序分析，为CAC1058→CAT1058的杂合和纯合多态性突变。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。