突变的

For investigation of genetic mechanisms of leaf polarity formation, we screened for Arabidopsis mutants with aber...

通过EMS化学诱变，寻找到一些形态相似，叶发育异常的突变体，遗传实验证明这些突变体可以被分成两类。

This mutation was found to be caused by a subsitution of an alanine residue at position 136 by an asparagine.

经鉴定，YPT1温敏突变是由于第136位的丙氨酸突变为天冬氨酸。

In the present study,using PCR amplification and automatic sequencing of EDA gene coding region,we report five mutations identified in 6 Chinese families with XLHED, including three novel ones:p.M1T,p.L62P and

其中3个点突变(p.M1T、p.L62P和p.G195E)为国际首次报道的新突变。

Drug-resistance mechanism to azole in Candida albicans is correlated with gene mutation of T199I and E165Y in ERG11 gene.

ERG11基因的E165Y突变和T199I突变与白假丝酵母对氟康唑耐药性有密切关系。

Department of Fish Ecology and Evolution, EAWAG Center of Ecology, Evolution and Biogeochemistry, 6047 Kastanienbaum, Switzerland

长期以来，学术界对自发突变机制的经典认识是，自发突变具有随机性和稀有性。

Error catastrophe theory has led to a strategy of mutagenesis to control disease viruses.

错误突变理论引导了通过突变来控制致病病毒的策略。

The result showed that the mutagenecity of water increased in all samples treated with chlorine, while mutagenic potential was negative in source water samples not treated with chorine.

水样采自某单位自备水源。试验结果表明，未氯化自来水有机提取物致突变反应阴性，加氯自来水样诱发沙门氏菌致突变率升高；在一定范围内，随氯浓度增加，不会显著增加水样的致突变性。

Among them, three were start codon deletions of the other three.

另外三个则是将三个缺失突变体的起始密码子突变掉。

Based on the structure, those human diseases related mutation sites are mapped onto the structure accurately. As a result, it is found that these sites are all around the electron transfer prosthetic groups or ubiquinone. And these mutations will alter prosthetic groups' binding or ubiquinone's binding, causing electron leakage from the prosthetic groups in the electron transfer chain, producing reactive oxygen species and leading to tumor formation.

利用线粒体复合物 II 的结构对已知与人类疾病相关的该复合物突变位点进行了精确定位，发现这些突变位点均位于电子传递体或辅酶 Q 结合位点的周围，它们的突变或影响了电子传递体的结合，或影响了辅酶 Q 的结合，从而导致电子传递的中断，电子逃逸到线粒体基质中或线粒体内膜中，经过一系列下游途径导致疾病的产生。

The VVA0326- mutant carrying a deletion of the GGDEF domain displayed smaller colony morphology on LB plate while compared to the wild type. No difference in colony forming units was found indicating that growth rate is not likely a major factor to confer the phenotype of small colony. In addition, VVA0326- appeared to swim better than wild type bacteria on the swimming plate. VVA0326- grew better, while VVA0328- mutant, which carried a deletion of the EAL domain, grew worse than wild type when the bacteria were cultured on CAS plate at 30°C. This implied that changes in surface structures of the mutants affected the bacterial susceptibilities to HDTMA contained in CAS plate.

缺损了包含一个GGDEF功能区域的突变株 VVA0326-，培养在LB的洋菜胶上，呈现出较小的生长菌落，在测定单位菌落数的结果发现，VVA0326-在生长速度上，相较於野生株并没有不同，因此我们推论生长速率并不是造成菌落变小的主要因子，除此之外，VVA0326-在游泳的分析培养皿中游的比野生株快，在CAS的分析培养皿上，与野生株比较，VVA0326-有比较好的生长状态，而缺损了包含一个EAL功能区域的突变株VVA0328-，却有被抑制生长的现象，可能是因为突变株影响了表面的结构，进而改变了细菌对於HDTMA的敏感层度。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。