突变的

This article reports the experimental results about y-ray induced chimaera of awned mutation in Mt generation of Triticum aestivum L.

在辐射诱变的实践中通常认为：M_1代所有的新的突变都将是杂合体，本文报道了用r-射线诱发长芒突变嵌合体的试验结果，并对嵌合体进行了遗传分析，结果表明：M_1代嵌合体的长芒突变是一种隐性基因突变，它可以是纯合突变。

Results Among 54 WD patients, 36 were found to carry Arg778leu mutation, among whom 15 were homozygote, 21 were heterozygote, the frequency of this mutation was 47.2%. Of 46 patients with hepatic damage, 36 were found to have the mutation of Arg778Leu, among whom 34 were found to have Leu770Leu polymorphism simultaneously.

结果 54例Wilson病患者中36例存在Arg778Leu基因突变，15例为纯合型，21例为杂合型，Arg778Leu等位基因突变频率为47.2 ％；46例伴肝损害的患者中33例存在ATP7B基因外显子8的Arg778Leu突变；36例Arg778Leu突变者中34例同时伴有Leu770Leu多态性。

Results 1555 mutation in the mitochondrial DNA was reverified to be one of the major factors which cause maternally inherited nonsyndromic deafness and the cosegregation of 955-960 and 1555 was present in this family.

结果再次证明了1555突变是该家系成员致聋的分子生物学基础之一；并发现该家系27名母系成员的线粒体基因组中除1555突变外，还同时存在有955-960同质型突变，两突变共分离。

AML patients with FLT3-LM was associated with a higher peripheral white cell count and a higher percentage of bone marrow blast cells but no lower complete remission rate tendency or shorer survival time camparing with FLT3-LM negative patients.

FLT3长度突变是AML中发生频率较高的一类突变；突变患者临床特征表现为外周血高白细胞，骨髓高原始细胞；FLT3长度突变与诱导缓解率和总生存时间无关。

The main results were showed as follows:Through screen and identification of morphology in M_2 and M_3, respectively, the mutants with mutative traits of plant were found. In which, 11 mutations were leaf variations, including light-green leaf, deep-green leaf, durative yellowish leaf, temporary yellowish leaf, inlaid yellowish leaf, wrinkly leaf, smooth-edged curly leaf, splitting-shaped curly leaf, peduncular-shaped leaf, round leaf and larger leaf, 12 were mutations on plant type, including excessive branches, lacking branches, highness, dwarf-like, erect posture, reclinate posture, strong stalk, slender stalk, tufty branches, wrinkled plant, purple stalk and hair-covered plant, 14 were flower variations, including dense flowers, light-yellow petals, white petals, white-mosaic petals, wrinkled petales, back-rolled petals, narrow petals, larger petals, smaller petals, apetalous flowers, variable-numbered petals, fertile pistil protraction, sterile pistil protraction and multi-anther, and 5 were physiologic mutants, including genic male sterile, cytoplasmic male sterile, bud-dead, and early and later bloom.

主要结果如下：通过田间M_2筛选和M_3重复鉴定，在田间农艺性状方面共获得浅绿叶色、深绿叶色、转绿黄化叶、持续黄化叶、边缘黄化叶、皱缩叶、光叶型卷叶、裂叶型卷叶、薹叶形叶、宽圆叶和大叶等11种不同的叶部性状突变体；同时还筛选到多分枝、少分枝、高杆、矮杆、株型紧凑、株型松散、粗茎、细茎、丛生分枝、整株皱缩、紫茎、整株被毛等12种植株性状突变体，密花、浅色花瓣、白色花瓣、白斑花瓣、皱瓣、卷瓣、窄瓣、大瓣、小瓣、无瓣、花瓣数目不定、可育型柱头外露、不育型柱头外露和多雄蕊等14种花器性状突变体，以及细胞核雄性不育、细胞质雄性不育、死蕾、早花和迟花等5种生理性状突变体。

Under the policy of discriminatory pricing, the catastrophic behavior of the transfer price is analyzed using hyperbolic umbilic catastrophe model.

在单一定价策略下，运用尖点突变模型研究了转移价格的突变行为；在差别定价策略下，运用双曲脐点突变模型研究了转移价格的突变行为。

The frequencies of CCR5delta32,CCR2b-64I,SDF1-3′A alleles in Dai population were 0.0000,0.2130,0.2030,respectively;The frequencies of CCR5delta32,CCR2b-64I,SDF1-3′A alleles in Chingpaw population were 0.000,0.1637,0.1770,respectively.Distributions of the CCR2b-64I,SDF1-3′A alleles among the both populations were in accordance with Hardy-Weinberg equilibrium.No statistical difference was found in the allelic frequencies of both CCR2b-64I and SDF1-3′A between male and female individuals.

结果表明，中国傣族景颇族人群中未发现CCR5△32等位基因突变；傣族CCR2b-64I、SDF1-3′A基因突变频率分别为0.2130和0.2030，景颇族CCR2b-64I和SDF1-3′A基因突变频率分别为0.1637和0.1770；与中国汉族人群相比较，傣族和景颇族中SDF1-3′A突变频率较低（P值分别为0.0322和0.0021）；两个民族的CCR2b-64I和SDF1-3′A等位基因群体分布符合Hardy-Weinberg平衡，在性别之间分布无显著差异。

These were raised underinducing condition to test if any morphology and structure changes. Twenty two Arabidopsismutants had various changes in morphology and anatomical structures. Twenty mutants hadlow germination rate from 10% to 60%, of which 2 had survival rates at 0% and 50%. Fivemutants occurred structure changes in the hypocotyls or stem. One of these lines, namedarris-stem, showed some unique changes: slower growth rate in comparison with the wildtype from germination to florescence; serrated margin of leaf blades, spiral rosette; morebranch in the bottom part of the stem, shorter nodes, twisted stem and branch. There were oneor several arrises along the stem. Across sections of the arrises showed one or several compactcells lumps which were round, made up of several layers of cells, looked like vascular-bundle.

在诱导条件下，这些突变体表现出不同的形态和结构的变化，共有22个表型和结构发生变化。20个突变系发芽率或存活率较低，发芽率由10％—60％，其中2个突变系存活率分别为0％和50％。5个突变系在茎或下胚轴的结构上发生变化，其中一个突变系arris-stem发生如下表型变化：从真叶出现至开花结实的整个生长期，生长速度要明显比野生型拟南芥缓慢；叶缘有明显锯齿，莲座叶呈螺旋状排列；茎的基部有较多侧枝，侧枝间距明显缩短，茎有明显扭曲；突变体茎侧面有1至数条棱形突起，内部存在一至数个排列紧密的细胞团，由多层细胞呈环形排列，细胞壁明显加厚，内部存在管状分子，推测为维管组织。

Four further single mutants ofN546(N546G,N546D,N546K,N546Δ), three double mutants and a triple mutant were constructed,and toxins were purified by isoelectric precipitation and an AKTA purifier 100 system.When bioassayed against H.armigera using purified toxins,N546ALC_(501.67μg/mLshowed 1.78 times increased toxicity than wide-type Cry1AcLC_(50 2.98μg/mL,and mutant N546D,N546K and N546Δshowed a great loss in toxicity.

对N546进一步突变，获得了突变子N546G、N546D、N546K和删除突变N546Δ及3个双突变和1个三突变，利用等电点沉淀法和AKTApurifier 100系统纯化了毒素蛋白，生测发现N546ALC_(50为1.67μg/mL对棉铃虫毒力比野生型Cry1AcLC_(50为2.98μg/mL提高了1.78倍，而N546D、N546K和N546Δ的毒力则降低了80～90%。

The antimutagenic and mutagenic activities of the three Rhizoma menispermi extracts were studied under the direct and indirect rapid synchronous test by using the bacterium enl tore technique.

采用细菌培养技术进行抗突变致突变直接及间接同步快速实验，以检测不同北豆根提取物的抗突变和致突变活性。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。