突变的

Nit mutants could be selected from chlorate-resistant sectors on Czapek but not on minimal medium . A total of 328 stable nit mutants were selected from 3504 sectors on Czapek and used for the further study. Of these nit mutants, 58. 8% were classed as nit1, 26. 8% as nit3, 13. 8% as NitM, 0.6% as nitD unable to from each isolate were complementally paired in all possible combination.

全部3504抗氯酸盐突变体在Czapek中共鉴定出328个稳定的nit突变体，其中nit1占58.8％，nit3占26.8％，NitM占13.8％，nitD占0.6％。37个菌株中，21个（73％）获得了nit突变体，16个（26％）还没有，仅5个菌株获得了NitM突变体。

To further understand mechanisms that control male gametogenesis and embryo development,we performed an genetic screen for mutations that caused distorted Mendelian segregation in Ac/Ds transposon system in Arabidopsis thaliana.

通过卡那霉素抗性(由突变体中标记基因编码)非孟德尔分离，从Ds插入的拟南芥突变体库中筛选到一个雄配子体发育突变体：ovp1和一个早期胚胎发生突变体eed1，我们对这两个突变体的表型和相关基因进行了研究。

Among these were one case with double mutations (D21S11 and PentaD) and another case with two different mutations (D7S820 and D16S539) in t...

在3764次减数分裂中，15个STR位点共观察到有72例突变，突变率为0 。128 %±1 。104×10-3.vWA和D21S11的突变率最高(0·292 %)，TH01和TPOX位点没有发现突变。

The relationship between the genetic deficiencies and hemorrhagic disorder were characterized. The homozygosity of the Thr359Met in the propositus with FⅦ: C activity 2% was related to severe clinical symptoms; The proband with double heterozygous lesions of Arg152Leu and one single nucleotide deletion at position 11487-9, combined with Arg304Trp in exon 8 with FⅦ activity 1% suffered severe clinical bleeding tendency. one proband with double heterozygous mutations (Agr304Trp and Arg304Gln) with 10% of FⅦ activities characterized asymptom. the heterozygous mutations (Thr359Met, Arg152Gln,-55C→T) with FⅦ: C 1%～5. 5% showed moderate or mild clinical symptoms.

其中8961 G＞T（Arg152Leu）和10966-8delC两种突变为国际首次报道，IFSla+5g＞a突变导致的异常剪接为国际首次报道。1个F7及F10基因联合缺陷家系，其中，F10基因28139 G＞T（Val384Phe）突变为国际首次报道；发现了1个由F7及组织因子(tissue factor，TF)两种基因联合缺陷导致的出血家系，其突变分别为F7基因启动子区-55C＞T杂合突变；TF 9363 C＞T（Arg131Trp）杂合多态性（频率2.63％）。6种F7基因突变发生在催化区；2种突变发生在裂解位点；1种发生在启动子区；1种突变发生在剪接位点，除一种缺失突变外，其余均为点突变；所有家系的基因突变都来自先证者的父亲和/或母亲。

After the selection from one to three generations, several mutants were obtained. The major mutants included non-nodule mutants (18 lines) which failed to nodulate after inoculated with rhizobia for two weeks, ineffective nodulation mutants (9 lines) which had less uneven and white or transparent nodules, an abnormal leaf and flower mutant which was dwarf without stipules, abnormal flowers and less nodules, and a slender mutant with a thin stem and smaller leaves.

从种植的三代植株中，筛选到多种共生固氮根瘤的突变体，其中不结根瘤突变体18个株系，表现为接种根瘤菌两周后无根瘤形成；结无效根瘤突变体9个株系，表现为根瘤数目少且分布不均匀，根瘤呈白色，有些为半透明；花叶形态异常突变体1个株系，表现为除根瘤数目少外，植株矮小、托叶消失、花形态异常；纤细突变体1个株系，表现为除根瘤数目少外，植株变小、茎细叶小。

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A type has 7 point mutations(5 samples). B type has 6 point mutations (3 samples), C type has 4 point mutations (3 samples) and D type has 2 point mutations(1sample). Acid amino alignment shows that the most mutations of gastric cancer are mis-sense mutations, few ones are synonymous mutations. Most of the mutations occurred in regulating domain down to the HMG-box,only 2 sites in HMG-box.The mutations have same sites in middle and late stage samples. The results revealed that SOX4 mutations are associated with gastric cancer,which is possible a late accident in gastric cancer.

通过对相应的氨基酸序列的比对发现，发生在中晚期胃癌中的突变多为错义突变，同义突变不多，且突变大多发生在HMG盒下游编码区，在HMG盒内的突变只有两处，中期胃癌与晚期胃癌的突变有相同之处，但SOX4基因的突变位点随肿瘤的演进有增加的趋势。

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Using fluid dynamics FEM (two dimensional, three dimensional andaxisymmetric) and three dimensional acoustic FEM in meticulous analysis ofexpansion muffler structure, this paper studies the influences of each mufflercomponents' position, dimension, form and quantity on the fluid dynamic andacoustic performances;therefore the paper indicates that the end of the intruding tubeis the linchpin of the fluid dynamic performance of the whole muffler structure, thespringhead of muffler fluid dynamic performance is the smoothness of air current, themain factor which affects the acoustic attenuation value of expansion chamber muffleris the grade of saltation of the section of air conducting access, and the attenuationvalue of specific frequency can be dramatically enhanced by carefully designing thelength of expansion chamber.

本文通过流体力学有限元方法和三维声学有限元方法对扩张腔消声结构的参数化模型进行了细致的分析，研究了这种结构的各个组成部份的位置、大小、形状和数量对其流体力学与声学性能的影响，指出插入管端口是影响整个结构流体力学性能的关键，消声结构流体力学性能的根源是气流通过时的平稳程度；影响扩张腔消声量的主要因素为声波传播通路截面突变的程度，并可以通过精细的设计扩张腔轴向长度获得宽频或指定频率消声量的大幅度提高。

It began with Kant that the view of history was applied to the study onthe nature. Later, Darwin and Clausius put forward two respectively contradictory views of history from the viewpoints of biological and non-biological systems, i.e. evolutionary and degenerate views of history, the theory of dissipatived structure established by prigogine solved the contradiction preli minarily. Prigogin...

指出康德首先将历史观引入到对自然界进行研究的；尔后达尔文和克劳胥斯分别从生物系统与非生物系统的角度出发提出了两种相矛盾的历史观，这就是进化的历史观与退化的历史观；普里高津建立的耗散结构理论初步解决了这一矛盾，他认为由大量子系统组织成的系统中的进化是由涨落的放大导致的，自组织系统中的断进化，本质上就是系统逐级突变的结果。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。